Articles tagged "Bile duct"

2020 American Transplant Congress
Temporal Trends in the Incidence and Impact of Biliary Complications Following Liver Transplantation
K. R. Jackson¹, K. Lentine², M. Schnitzler², Z. Zhang², H. Xiao², J. Motter¹, D. Axelrod³, D. Segev¹
¹Johns Hopkins University, Baltimore, MD, ²Saint Louis University, Saint Louis, MO, ³University of Iowa, Iowa City, IA
*Purpose: Biliary complications (BC) are a major threat to successful liver transplantation (LT), as they are associated with a subsequent higher risk of mortality and…
2020 American Transplant Congress
Post Liver Transplant Biliary Complications in the Post HCV Era
M. Birch, K. Halazun, D. Tsapepas, C. Brenna, B. Samstein
New York Presbyterian - Weill Cornell Medical Center, New York, NY
*Purpose: Biliary complications in the post HCV era has not been well defined.*Methods: We retrospective studied 209 patients transplanted from April 2015 to November 2019…
2020 American Transplant Congress
Percutaneous Choledochoscopy and Laser Biliary Stricturoplasty: A Case Series of Novel Management of Refractory Post-Liver Transplant Biliary Complications
W. E. Jackson¹, P. S. Trivedi², J. J. Pomposelli³, T. J. Pshak³
¹Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, ²Division of Vascular and Interventional Radiology, University of Colorado, Aurora, CO, ³Division of Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Anastomotic biliary strictures are a well-recognized complication after living and deceased donor liver transplant (LDLT and DDLT). Management focuses on utilizing endoscopic retrograde cholangiography…
2020 American Transplant Congress
3D Bioprinted Intrahepatic Cholangiocarcinoma Model and 7-Day Perfusion with Gemcitabine and Cisplatin: Modeling the Tumor Microenvironment and Response to Chemotherapy
A. M. Chen¹, W. Zhang¹, J. Sterner², L. Kennedy³, A. Isidan¹, E. Gramelspacher¹, H. L. Francis³, G. Alpini³, L. J. Smith², P. Li¹, B. Ekser¹
¹Division of Transplant Surgery - Indiana University, Indianapolis, IN, ²3D Bioprinting Core and Department of Radiology and Imaging Sciences - Indiana University, Indianapolis, IN, ³Division of Gastroenterology, Richard L. Roudebush VA Medical Center and Indiana University, Indianapolis, IN
*Purpose: Over 8,000 patients are newly diagnosed with cholangiocarcinoma (CCA) in the United States each year.Understanding the CCA microenvironment will facilitate the development of novel…
2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Y. L. Boteon, J. Attard, A. P. Boteon, L. Wallace, G. Reynolds, D. Mirza, H. Mergental, R. Bhogal, S. Afford
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…
2019 American Transplant Congress
Normothermic Ex-Situ Liver Perfusion Parameters of Liver Viability in a Porcine Model of Liver Transplantation with Marginal Grafts
I. Linares-Cervantes¹, J. Echeverri¹, S. Cleland¹, M. Kaths¹, R. Rosales¹, T. Goto¹, D. Kollmann¹, M. Hamar¹, P. Urbanellis¹, L. Mazilescu¹, S. Ganesh¹, O. Adeyi¹, P. Yip¹, B. Bojko², P. Gorynzka², K. Gorynski², D. Grant¹, N. Selzner¹, M. Wasowicz¹, M. Selzner¹
¹Toronto General Hospital, Toronto, ON, Canada, ²University of Nicolaus Copernicus, Torun, Poland
*Purpose: Evaluate parameters of liver viability during normothermic ex-situ liver perfusion (NEsLP) prior to transplantation.*Methods: In this study, we investigated prior assessed parameters and new…
2019 American Transplant Congress
Bile Duct Anastomosis over Intraluminal Plastic Biliary Stent in Liver Transplant: Clinical Outcome
H. Samant¹, K. Patel¹, W. Manatsathit², N. Singh¹, H. S. Amiri³, G. Zibari³
¹Louisiana State University and Health Science Center, Shreveport, LA, ²University of Nebraska Meical Center, Omaha, NE, ³John C McDonald Transplant Center, Shreveport, LA
*Purpose: Biliary complications have been known as “Achilles Heel” of orthotropic liver transplantation (OLT) with high morbidity and mortality. Intra-luminal plastic biliary stents replacing T-tubes…
2019 American Transplant Congress
Insertion of Internal Stent in Duct-to-Duct Biliary Reconstruction to Reduce Bile Duct Complication in Living Donor Liver Transplantation
H. Choi¹, G. Na²
¹Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea, Republic of, ²Surgery, Bucheon St. Mary's Hospital, The Catholic University of Korea, Bucheon, Korea, Republic of
*Purpose: Because of the innovations in surgical and postoperative surgical treatment of donors and recipients during the past decade, living donor liver transplantation (LDLT) is…
2019 American Transplant Congress
Management of Orphan Ducts After Pediatric Living Donor Liver Transplantation
N. Celik¹, A. Ganoza², A. Khanna², G. Bond², K. Soltys², R. Sindhi², J. Crowley³, A. Humar¹, G. Mazariegos²
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Department of Radiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: Living donor (LDLT) and split (SLT) livers are two technical variants of standard liver transplants that potentially increase the number of liver allografts available…
2019 American Transplant Congress
Scaffold-Free 3D-Bioprinting of Human Extrahepatic Bile Duct
K. Saglam¹, W. Zhang¹, L. J. Smith², A. Isidan¹, A. M. Chen¹, R. A. Naqvi¹, E. Gramelspacher¹, P. Li¹, B. Ekser¹
¹Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN, ²3D-Bioprinting Core, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Biliary complications are common especially in living and also in deceased donor liver transplantation (LT). Presence of multiple orifices in biliary anastomosis and ischemia,…