Articles tagged "Bile duct"

2020 American Transplant Congress
Temporal Trends in the Incidence and Impact of Biliary Complications Following Liver Transplantation
K. R. Jackson¹, K. Lentine², M. Schnitzler², Z. Zhang², H. Xiao², J. Motter¹, D. Axelrod³, D. Segev¹
¹Johns Hopkins University, Baltimore, MD, ²Saint Louis University, Saint Louis, MO, ³University of Iowa, Iowa City, IA
*Purpose: Biliary complications (BC) are a major threat to successful liver transplantation (LT), as they are associated with a subsequent higher risk of mortality and…
2020 American Transplant Congress
Post Liver Transplant Biliary Complications in the Post HCV Era
M. Birch, K. Halazun, D. Tsapepas, C. Brenna, B. Samstein
New York Presbyterian - Weill Cornell Medical Center, New York, NY
*Purpose: Biliary complications in the post HCV era has not been well defined.*Methods: We retrospective studied 209 patients transplanted from April 2015 to November 2019…
2020 American Transplant Congress
Percutaneous Choledochoscopy and Laser Biliary Stricturoplasty: A Case Series of Novel Management of Refractory Post-Liver Transplant Biliary Complications
W. E. Jackson¹, P. S. Trivedi², J. J. Pomposelli³, T. J. Pshak³
¹Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, ²Division of Vascular and Interventional Radiology, University of Colorado, Aurora, CO, ³Division of Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Anastomotic biliary strictures are a well-recognized complication after living and deceased donor liver transplant (LDLT and DDLT). Management focuses on utilizing endoscopic retrograde cholangiography…
2020 American Transplant Congress
3D Bioprinted Intrahepatic Cholangiocarcinoma Model and 7-Day Perfusion with Gemcitabine and Cisplatin: Modeling the Tumor Microenvironment and Response to Chemotherapy
A. M. Chen¹, W. Zhang¹, J. Sterner², L. Kennedy³, A. Isidan¹, E. Gramelspacher¹, H. L. Francis³, G. Alpini³, L. J. Smith², P. Li¹, B. Ekser¹
¹Division of Transplant Surgery - Indiana University, Indianapolis, IN, ²3D Bioprinting Core and Department of Radiology and Imaging Sciences - Indiana University, Indianapolis, IN, ³Division of Gastroenterology, Richard L. Roudebush VA Medical Center and Indiana University, Indianapolis, IN
*Purpose: Over 8,000 patients are newly diagnosed with cholangiocarcinoma (CCA) in the United States each year.Understanding the CCA microenvironment will facilitate the development of novel…
2019 American Transplant Congress
Management of Orphan Ducts After Pediatric Living Donor Liver Transplantation
N. Celik¹, A. Ganoza², A. Khanna², G. Bond², K. Soltys², R. Sindhi², J. Crowley³, A. Humar¹, G. Mazariegos²
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Department of Radiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: Living donor (LDLT) and split (SLT) livers are two technical variants of standard liver transplants that potentially increase the number of liver allografts available…
2019 American Transplant Congress
Scaffold-Free 3D-Bioprinting of Human Extrahepatic Bile Duct
K. Saglam¹, W. Zhang¹, L. J. Smith², A. Isidan¹, A. M. Chen¹, R. A. Naqvi¹, E. Gramelspacher¹, P. Li¹, B. Ekser¹
¹Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN, ²3D-Bioprinting Core, Indiana University School of Medicine, Indianapolis, IN
*Purpose: Biliary complications are common especially in living and also in deceased donor liver transplantation (LT). Presence of multiple orifices in biliary anastomosis and ischemia,…
2019 American Transplant Congress
Hepatopancreatobiliary Training In Transplant Fellowships: H And B, Maybe?
R. Borscheid¹, A. Saharia², E. Cho¹, F. Lewis¹, H. Osman¹, J. Kurtz¹, D. Jeyarajah¹, A. Gaber²
¹Methodist Richardson Medical Center, Richardson, TX, ²Houston Methodist Hospital, Houston, TX
*Purpose: HPB surgery is an evolving specialty, but only about 15% of the active HPB surgeons have undergone training in a dedicated HPB program -…
2019 American Transplant Congress
Management of Anastomotic Biliary Strictures after Liver Transplant: Role of Covered Metal Stents
A. Watson¹, K. Haq¹, K. Khorfan², S. Singla¹, A. Yoshida³, D. Moonka¹
¹Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ²Internal Medicine, Henry Ford Hospital, Detroit, MI, ³Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Biliary complications, including anastomotic biliary strictures (ABS), remain the most common cause of morbidity in liver transplant (LT) patients. Endoscopic therapy has become the…
2019 American Transplant Congress
Epithelial to Mesenchymal Transition: A Cellular Mediator of Ischemic Cholangiopathy after Liver Transplant
N. A. Wickramaratne¹, R. Li², R. C. Fyffe-Freil², T. Tian², M. J. Mangino²
¹VCUHealth, Richmond, VA, ²Department of Surgery, VCUHealth, Richmond, VA
*Purpose: Epithelial-to-mesenchymal transition (EMT) is a genetic reprogramming that causes epithelial cells to assume a migratory, mesenchymal phenotype, and it is induced by hypoxia. Ischemic…
2019 American Transplant Congress
Ischemia-Free Liver Transplantation Protects Bile Duct from Ischemia/Reperfusion Injury
J. Yang, S. Huang, Z. Zhang, Q. Zhao, W. Ju, Z. Zhu, Y. Tang, L. Wang, Y. Zhang, C. Sun, L. Wu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Ischemia-free liver transplantation (IFLT), based on normothermic machine perfusion and innovations in surgical technique, can provide continue blood supply from procurement to implantation that…