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Articles tagged "Antilymphocyte antibodies"

  • 2015 American Transplant Congress

    Antithymocyte Globulin-Induced Platelet Hypercoagulability Is a Consequence of Complement Activation and Microvesicle Release

    D. Zecher,1,4 A. Cumpelik,1 D. Tsakiris,2 M. Dickenmann,3 J. Schifferli.1

    1Department of Research, Basel University Hospital, Basel, Switzerland; 2Department of Hematology, Basel University Hospital, Basel, Switzerland; 3Department of Nephrology, Basel University Hospital, Basel, Switzerland; 4Department of Nephrology, Regensburg University Hospital, Regensburg, Germany.

    T cell depletion with antithymocyte globulins (ATG) can be complicated by thrombopenia andhypercoagulability. The underlying mechanism is still unclear. We found that binding of ATG…
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