2020 American Transplant Congress
Less Bleeding Associated with Apixaban versus Other Direct Acting Oral Anticoagulation in Solid Organ Transplant Recipients
*Purpose: Owing to their fixed dosing and favorable drug interaction profiles, direct acting oral anticoagulants (DOACs) have supplanted warfarin as the standard of care for…2020 American Transplant Congress
Anticoagulation in Simultaneous Pancreas Kidney (SPK) Transplantation- On What Basis?
Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
*Purpose: Despite technical refinements, early pancreas graft loss due to thrombosis continues to occur. Conventional coagulation tests do not detect hypercoagulability and hence is left…2020 American Transplant Congress
Safety and Efficacy of Direct-Acting Oral Anticoagulants versus Warfarin in Kidney Transplant Recipients
*Purpose: Safety and efficacy of direct-acting oral anticoagulants (DOACs) have not been well studied in solid organ transplant. The purpose of our study was to…2020 American Transplant Congress
Adult Liver Transplant Recipients Show Increased Fibrinolysis Resistance Compared with Pediatric Recipients: The Potential Impact of Anticoagulation between the Two Populations
University of Colorado, Aurora, CO
*Purpose: Fibrinolytic changes in adult liver transplant patients have previously been demonstrated large transitions from excessive fibrinolysis (hyperfibrinolysis) to fibrinolysis resistance (shutdown) within 2 hours…2020 American Transplant Congress
Utilization of Direct Acting Oral Anticoagulation in Solid Organ Transplant Patients: A National Survey of Institutional Practices
*Purpose: The safety and efficacy of direct acting oral anticoagulants (DOACs) and reversal strategies are not well established in the solid organ transplant population. This…2020 American Transplant Congress
Evaluation of Apixaban Usage in Solid Organ Transplant Patients with Renal Impairment
Pharmacy, CHI St. Luke's Health-Baylor St. Luke's Medical Center, Houston, TX
*Purpose: There remains a gap in the literature for apixaban dosing recommendations for treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE) in special…2020 American Transplant Congress
The Effects of Rivaroxaban and Apixaban on Tacrolimus Pharmacokinetics
*Purpose: To clarify the pharmacokinetic impact of rivaroxaban (RIVA) and apixaban (APIX) on tacrolimus (TAC) concentrations.*Methods: Solid organ transplant recipients 18-years or older who were…2020 American Transplant Congress
Perioperative Anticoagulation Decreases Graft Thrombosis in Pancreas Transplantation
*Purpose: Pancreas transplant thrombosis is the most common cause of graft failure in the early postoperative period, occurring 5-20% of cases. Bleeding (which occurs ~30%…2020 American Transplant Congress
Evaluation of Clinical Outcomes in Patients Receiving Antithrombotic Therapy Prior to Kidney Transplantation
*Purpose: Patients with end stage renal disease (ESRD) often have significant cardiovascular comorbidities. Utilization of therapeutic anticoagulation (AC) and/or antiplatelet (AP) therapy poses an increased…2020 American Transplant Congress
Is Bridging Anticoagulation or Antiplatelet Reversal Necessary Prior to Kidney Transplantation?
AHN Transplant Institute, Allegheny General Hospital, Pittsburgh, PA
*Purpose: Pre-kidney transplant patients are often placed on anticoagulation or antiplatelet therapy, and their perioperative management is often challenging. The aim of this study is…
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