Articles tagged "Adverse effects"

2021 American Transplant Congress
Outcomes of Granulocyte-Colony Stimulating Factor Use in Pediatric Renal Transplant Recipients: A Pediatric Nephrology Research Consortium Study
R. M. Engen¹, P. L. Weng², W. Shih³, H. Patel⁴, K. Richardson⁵, S. Dowdrick⁶, I. Ashoor⁷, J. Misurac⁸, A. Z. Traum⁹, M. Semanik¹⁰, N. G. Jain¹¹, R. Sreedharan¹²
¹Northwestern University, Chicago, IL, ²University of California Los Angeles, Los Angeles, CA, ³University of Michigan, Ann Arbor, MI, ⁴Nationwide Children's Hospital, Columbus, OH, ⁵Oregon Health & Science University, Portland, OR, ⁶Penn State Health, Hershey, PA, ⁷Louisiana State University, New Orleans, LA, ⁸University of Iowa, Iowa City, IA, ⁹Harvard University, Boston, MA, ¹⁰University of Wisconsin-Madison, Madison, WI, ¹¹Columbia University, New York, NY, ¹²Medical College of Wisconsin, Milwaukee, WI
*Purpose: Neutropenia is common after pediatric kidney transplant and is associated with an increased risk of bacterial infection, allograft loss, and death. Granulocyte colony-stimulating factor…
2021 American Transplant Congress
Non-Alcoholic Fatty Liver Disease in Non-Liver Transplant Patients
R. Claudio¹, C. Conceicao², K. Robichaux², A. Kumar¹, J. Buggs³, N. Kemmer⁴
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of South Florida, Tampa, FL, ³Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁴Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: The global prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an alarming rate, driven in large part by an increased incidence of…
2020 American Transplant Congress
Largest Experience of Safety, and Efficacy of Patiromer in Solid Organ Transplants (SOT)
P. Singh¹, H. Winters², T. E. Pesavento¹, K. Schnelle²
¹Transplant Nephrology, Ohio State University, Columbus, OH, ²Transplant Pharmacy, Ohio State University, Columbus, OH
*Purpose: Hyperkalemia, a potentially life‐threatening electrolyte abnormality, is commonly seen SOT. The predisposing factors are renal-dysfunction, and medications (CNI, TMP-SMX, ACEI, and ARBs). Patiromer, a…
2020 American Transplant Congress
Effects of Tenofovir and Entecavir on Glomerular Kidney Function in Liver Transplant Patients: A Nationwide Cohort Study
J. Lee¹, E. Kim¹, S. Yang¹, S. Kim¹, J. Lee¹, J. Park², H. Choi³, B. Kim², D. Joo¹, S. Kim¹, M. Kim¹
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of
*Purpose: Entecavir and tenofovir are currently the first-line drugs in liver transplantation (LT) patients for the prevention of hepatitis B virus recurrence. Despite its proven…
2020 American Transplant Congress
Outcomes of Kidney Transplant Recipients with Depression and Anxiety
D. Keys, S. Jackson, S. M. Riad, R. Spong, A. Matas
University of Minnesota, Minneapolis, MN
*Purpose: The outcomes of kidney transplantation in patients with depression and anxiety have been limited by small numbers. This is despite high prevalence of these…
2020 American Transplant Congress
An Evaluation of Converting Elderly Kidney Transplant Recipients from Tacrolimus to LCPT to Limit Neurological Adverse Events and Improve Quality of Life
A. Reticker, B. Valdepenas, K. Bruno, D. Cikopana, S. Walton, E. Benedetti, I. Tzvetanov, P. West-Thielke
University of Illinois, Chicago, IL
*Purpose: Adverse effects (AEs) of tacrolimus significantly reduce recipients’ quality of life (QOL). Given its ability for tremor improvement, this study investigates whether conversion from…
2020 American Transplant Congress
Relationship between Tacrolimus Levels and Short-Term Outcome in Korean Pediatric Patients with Liver Transplantation
H. Lim¹, H. Koh¹, S. Kim¹, S. Park¹, Y. Kang², M. Kim³, K. In¹
¹Severance Pediatric Liver Diseases Research Group, Severance Children’s Hospital, Severance Hospital, Seoul, Korea, Republic of, ²Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, , Wonju Severance Christian Hospital, Seoul, Korea, Republic of, ³Division of Transplantation Surgery, Department of General Surgery, Severance Hospital, Seoul, Korea, Republic of
*Purpose: Liver transplantation (LT) is a life-saving procedure in patients with end stage liver disease. After LT, immunosuppresive regimens are needed in order to prevent…
2020 American Transplant Congress
Long Term Ursodeoxycholic Acid Use Does Not Alter Long Term Rejection, Biliary Complication, Mortality or Hospitalization Rates after Liver Transplantation
T. Ashraf¹, V. Mendiratta², S. Gill¹, A. Abdelwahab³, D. Moonka², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ³Wayne State University, Detroit, MI
*Purpose: Endogenous bile acids are suspected to contribute to hepatobiliary injury after liver transplantation through direct cytotoxic effects. Ursodeoxycholic acid (UDCA) has been shown to…
2020 American Transplant Congress
Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment
I. H. Song¹, K. Ilic², J. Wu³
¹Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, ²Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, ³Biostat, Shire, a Takeda Company, Lexington, MA
*Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
2020 American Transplant Congress
Optimal Transition for Transplant Recipients: A Model of Care in an Integrated Health Care System
S. Zheng¹, L. Pravoverov¹, A. Nazarova¹, D. Adey², N. B. Goes¹
¹The Permanente Medical Group, San Francisco, CA, ²Kidney and Transplantation Program, University of California San Francisco, San Francisco, CA
*Purpose: Transplantation is the treatment of choice for ESRD. While short-term outcomes have improved, long-term outcomes lag. Many factors may explain the long-term lag including…

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