2018 American Transplant Congress
Metabolic Complications 10-Years after Kidney Transplant
Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…2018 American Transplant Congress
Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant
Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…2018 American Transplant Congress
Association between Everolimus Trough Levels, Onset of Related Adverse Events, and Treatment Discontinuation after Liver Transplantation: 24-Month Results from the H2304 Study
Purpose: Evaluation of mammalian target of rapamycin inhibitor (mTORi)-related adverse events (AEs) and drug trough levels (C0) at onset may aid their management in liver…2018 American Transplant Congress
Preventing Recurrence of Incisional Hernia after Liver Transplantation
Transplant Surgery, Indiana University, Indianapolis, IN.
Background: Incisional hernia is a well-known complication of orthotopic liver transplantation (OLT). Although factors that affect incidence of hernia after OLT have been described, recurrence…2018 American Transplant Congress
Post-Hoc Analysis of Everolimus Trough Levels around the Onset of Related Adverse Events and Treatment Discontinuation in De Novo Kidney Transplant Recipients from the US92 Study
1US92 Study Group, Salt Lake City; 2Novartis Pharmaceutical Corporation, East Hanover.
Purpose: Around 30%-50% of kidney transplant recipients (KTR) on sirolimus discontinue treatment due to drug-related adverse events (AE) and ~23% on everolimus (EVR) discontinue treatment…2018 American Transplant Congress
Closing Pandora's Box: An Evidence Based Approach to Opioid-Tolerant Patients Following Transplantation. The Case for IV Methadone
Department of Surgery, Beaumont Health, Royal Oak, MI.
The purpose of this study is to explore the use of parenteral methadone in opioid-tolerant patients who are status-post transplantation. As an alternative to traditional…2018 American Transplant Congress
Renal-Sparing Protocol May Be Harmful If Performed Early Post-Heart Transplant
Cedars Sinai Medical Center, Los Angeles, CA.
Purpose: Calcineurin inhibitors (CNIs) are associated with nephrotoxicity. Renal sparing protocol (RSP) with CNI free regimen using mycophenolate and a proliferation signal inhibitor may improve…2018 American Transplant Congress
Patient Experience after Kidney Transplant: Factors That Lessen the Burden of Treatment after Kidney Transplant
1Mayo Clinic, Rochester; 2Mayo Clinic, Scottsdale; 3Mayo Clinic, Jacksonville.
Background: Patients face a daunting regimen of medications, health monitoring and medical appointments following kidney transplant. This workload of healthcare and its impact on patient…2018 American Transplant Congress
Belatacept and Tacrolimus Corticosteroid-Free Regimens Lead to Elevated Mycophenolic Acid Exposure at 1 and 3 Months after Kidney Transplantation
Mycophenolate mofetil (MMF) is generally administered as a fixed dose. Studies have shown a relationship between MPA exposure (MPAAUC) but no data evaluates this relationship…2018 American Transplant Congress
Efficacy and Safety of a Single-Dose Rituximab for Prevention of Focal Segmental Glomerulosclerosis Recurrence after Kidney Transplant
Background: For patients with end stage renal disease (ESRD) due to primary focal segmental glomerulosclerosis (FSGS), there is a significantly increased risk for disease recurrence…
American Transplant Congress abstracts