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American Transplant Congress abstracts

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Articles tagged "Adverse effects"

  • 2022 American Transplant Congress

    Pericardial Effusion: A Potential Late Complication of COVID-19 Infection

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…
  • 2022 American Transplant Congress

    Incidence of Dapsone-Induced Methemoglobinemia in Solid Organ Transplant Recipients

    D. Quan1, R. Gordon1, J. Lee1, D. Khoshabafard2, A. Han1

    1Pharmacy, UCSF Medical Center, San Francisco, CA, 2Clinical Phamacy, UCSF School of Pharmacy, San Francisco, CA

    *Purpose: The purpose of this study was to determine the incidence of dapsone-induced methemoglobinemia in solid organ transplant recipients.*Methods: This was a single-center retrospective cohort…
  • 2022 American Transplant Congress

    Physiological Age by Artificial Intelligence-Enhanced Electrograms as a Novel Biomarker of Mortality in Kidney Transplant Candidates

    E. Lorenz, I. Zaniletti, B. Johnson, T. Petterson, W. Kremers, C. Schinstock, H. Amer, A. Cheville, N. LeBrasseur, A. Baez-Suarez, Z. Attia, F. Lopez-Jimenez, P. Friedman, C. Kennedy, A. Rule

    Mayo Clinic, Rochester, MN

    *Purpose: Assessing mortality risk prior to kidney transplantation is challenging. Age-Gap, which is the difference between physiological age determined by artificial intelligence-enhanced electrocardiograms (ECG) and…
  • 2022 American Transplant Congress

    Transplant Graft TMA Injury Post COVID-19 Vaccination

    O. Sogbein, A. Rizvi, M. Mujtaba, S. Hussain

    Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX

    *Purpose: Vaccination against SARS-CoV-2 is essential. Complicating this effort are reports of a suboptimal response to the SARS-CoV-2 spike protein in patients on immunosuppressive medications…
  • 2022 American Transplant Congress

    Maribavir (MBV) versus Investigator-Assigned Therapy (IAT) for Refractory Cytomegalovirus (CMV) Infection (with or without Resistance) in Solid Organ Transplant (SOT) Recipients: Subgroup Safety Analysis of a Phase 3 Study

    R. M. La Hoz1, D. Florescu2, D. Kumar3, F. Saliba4, J. Gu5, A. Sundberg5

    1Univ. Texas Southwestern Medical Center, Dallas, TX, 2Univ. Nebraska Medical Center, Omaha, NE, 3Univ. Health Network, Toronto, ON, Canada, 4Univ. Paris Saclay, Paris, France, 5Takeda Development Center Americas, Inc., Lexington, MA

    *Purpose: In a Phase 3 study of MBV vs IAT (val/ganciclovir, foscarnet, or cidofovir) for refractory CMV infection (with/without resistance; R/R) in hematopoietic cell transplant…
  • 2022 American Transplant Congress

    Telemedical Surveillance and Optimized Treatment of Blood Pressure in Kidney Transplant Recipients

    W. Düttmann1, M. G. Naik1, B. Zukunft1, B. Osmanodja1, G. Eleftheriadis1, S. Ronicke2, M. Choi1, F. Bachmann1, F. Halleck1, K. Budde1

    1Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Patients with chronic kidney disease suffer often from cardiovascular diseases, especially high blood pressure and its complications such as stroke and heart attack. After…
  • 2022 American Transplant Congress

    An Interim Report on a Prospective Randomized Trial of Extended-Release Tacrolimus in Liver Transplantation with Anti-Thymocyte Induction in a Steroid Free Protocol

    R. A. Helmick, S. Naik, C. Eymard, J. Eason, J. Vanatta

    James D. Eason Transplant Institute at Methodist University Hospital and University of Tennessee Health Science Center, Memphis, TN

    *Purpose: Our study hypothesis was that once daily dosing of extended-release tacrolimus (ERT) would be a safe and effective immunosuppression (IS) with the potential to…
  • 2022 American Transplant Congress

    Impact Of Nirmatrelvir-Ritonavir On Tacrolimus Concentrations

    S. Fredrick1, B. Wise2, L. Bowman2, D. DeWolfe1, J. Taylor1, J. Melaragno1

    1University of Rochester Medical Center, Rochester, NY, 2Tampa General Hospital, Tampa, FL

    *Purpose: Ritonavir (RTV), a component of the oral antiviral agent nirmatrelvir-RTV (Paxlovid) for COVID-19 infection, increases tacrolimus concentrations through strong competitive inhibition of gastrointestinal and…
  • 2022 American Transplant Congress

    Clinical Outcomes with IR-tac to LCP-tac Conversion in a Kidney Transplant Population

    F. Bartlett1, J. Newman1, T. Sprague1, S. Patel1, N. Rao2, E. Andrade2, V. Rohan2, M. Casey2, D. Dubay1, D. Taber1

    1Pharmacy, Medical University of South Carolina, Charleston, SC, 2Medical University of South Carolina, Charleston, SC

    *Purpose: LCP-Tac is approved for conversion from IR-Tac in kidney transplant patients with a conversion rate of 70-80%. Studies have demonstrated similar efficacy and safety…
  • 2022 American Transplant Congress

    Incidence and Risk Factors Associated with the Development of Hypoglycemia After Combined Pancreas-Kidney Transplantation

    S. Kapoor1, S. Jain2, S. Stefan3, Y. Azzi3, M. Ajaimy3, P. Loarte-Campos3, C. Pynadath3, H. C. Yaffe3, M. Le3, J. Rocca3, S. Greenstein3, M. Kinkhabwala3, J. Graham3, E. Akalin4, L. Liriano-Ward3

    1Montefiore Medical Center, New York, NY, 2Montefiore Medical Center, Scarsdale, NY, 3Montefiore Medical Center, Bronx, NY, 4Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY

    *Purpose: To review the incidence of hypoglycemia after pancreas transplantation in recipients with type 1 and 2 diabetes mellitus and the risk factors associated with…
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