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Articles tagged "Adverse effects"

  • 2015 American Transplant Congress

    Systematic Medical Record Review to Identify Safety Risks in Living Liver Donors

    B. Platt,5 D. Woods,5 R. Fisher,2 J. Guarrera,3 E. Pomfret,4 M. Simpson,4 A. Daud,1 T. Curtis,5 E. Reyes,5 E. Wymore,5 A. Skaro,1 D. Ladner.1

    1Northwestern University, Chicago, IL; 2Virginia Commonwealth University, Richmond, VA; 3Columbia University, New York, NY; 4Lahey Clinic, Boston, MA; 5CHS, Northwestern University, Chicago, IL.

    BACKGROUNDPrevention of adverse events (AEs) is important in Living Donor Liver Transplantation (LDLT), as these are healthy volunteers who undergo a major procedure with no…
  • 2015 American Transplant Congress

    ABCB1 Haplotypes, Sex, Calcineurin Inhibitors and Lipid Profiles Post-Renal Transplant

    C. Meaney,1,2 R. Venuto,3 D. Brazeau,4 J. Consiglio,5 L. Cooper,1 G. Wilding,5 K. Tornatore.1,2,3

    1NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY; 2School of Pharmacy, Buffalo, NY; 3Medicine, School of Medicine, Buffalo, NY; 4University of New England College of Pharmacy, Portland, ME; 5Biostatistics, School of Public Health, University at Buffalo, Buffalo, NY.

    Purpose: Hyperlipidemia is common in renal transplant recipients (RTR) during calcineurin inhibitor (CNI) immunosuppression. P-glycoprotein (P-gp) is an efflux transporter encoded by ABCB1 that modulates…
  • 2015 American Transplant Congress

    Risks for Readmission Post-Renal Transplant: A Co-Morbid Condition

    M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Background: Recently CMS addressed “excessive” readmission rates with a punitive 5% cut in reimbursement. For decades renal transplantation has been highly regulated with published outcomes…
  • 2015 American Transplant Congress

    Medication Adherence and Treatment Satisfaction in Liver Transplant Recipients

    A. Albekairy,1 A. Alkatheri,2 N. Khalidi,2 K. Thiab,1 A. Jarab,2 A. Qandil,3 A. Alshaya,2 K. BinSaleh.2

    1Pharmaceutical Care Department, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia; 2Pharmacy Practice, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 3Pharmaceutical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

    Background: Research has indicated that adherence to medication in patients with liver transplant is poor and considered as one of the main barriers to the…
  • 2015 American Transplant Congress

    Safety and Outcome of Ganciclovir-Resistant CMV Treated With Foscarnet: A Single Center Retrospective Study

    B. Pierce,4 C. Richardson,4 K. Cunningham,4 C. D'Agostino,4 C. Tseng,4 J. Brown,4 C. O'Brien,4 B. Ho,1,3,5 M. Ison.1,2,3

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Division of Infectious Diseases, Northwestern Medicine, Chicago, IL; 3Division of Organ Transplantation, Northwestern Medicine, Chicago, IL; 4Pharmacy, Northwestern Medicine, Chicago, IL; 5Transplant Nephrology, Northwestern Medicine, Chicago, IL.

    Background: Infection with cytomegalovirus (CMV) is an important cause of morbidity and mortality following solid organ transplantation (SOT). Resistance can rarely develop via mutations in…
  • 2015 American Transplant Congress

    Clinically Relevant Wound Events With Everolimus-Based Immunosuppressive Regimen: Post-Hoc Analysis from a Randomized Heart Transplant Study

    A. Zuckermann,1 M. Rinaldi,1 N. Yonan,1 S.-S. Wang,1 G. Dong,2 P. Lopez.2

    1For the A2309 Study Group, Vienna, Austria; 2Novartis, Basel, Switzerland.

    Purpose: In the A2310 (NCT00300274) heart transplant (HTx) study with everolimus (EVR) vs mycophenolate mofetil (MMF), information on a broad spectrum of potential wound healing…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Has Been Safe in the United Kingdom and Achieves Long-Term Steroid Avoidance in More Than 80% of Low Risk Renal Transplant Recipients

    A. Seitz,1 M. Robb,3 S. Balasubramanian,1 A. McLean,2 D. Taube,2 R. Johnson,3 R. Baker.1

    1Renal Unit, St. James's Hospital, Leeds, United Kingdom; 2West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom; 3Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom.

    Introduction: The use of alemtuzumab as an induction agent for renal transplantation is increasing in the UK. There is some evidence to suggest that this…
  • 2015 American Transplant Congress

    Associations of Pre-Transplant Prescription Narcotic Use With Clinical Complications After Kidney Transplantation

    N. Lam,1 M. Schnitzler,2 J. Tuttle-Newhall,2 H. Xiao,2 D. Axelrod,3 D. Brennan,4 V. Dharnidharka,4 M. Nazzal,2 K. Lentine.2

    1Western University, London, ON, Canada; 2Saint Louis University, St. Louis, MO; 3Dartmouth Hitchcock Medical Center, Hanover, NH; 4Washington University School of Medicine, St. Louis, MO.

    Background: Associations of narcotic use before kidney transplantation with post-transplant clinical outcomes are not well described.Methods: We performed a retrospective analysis of linked national registry…
  • 2015 American Transplant Congress

    Adverse Events of Maintenance Immunosuppression Following Kidney Transplantation Reported in Randomized Controlled Trials: A Systematic Review

    M. Howell,1,2 R. Yeo,2 A. Tong,1,2 J. Craig,1,2 K. Howard,2 G. Wong.2,3

    1Centre for Kidney Research, The Children's Hospital at Westmead, Westmeand, NSW, Australia; 2School of Public Health, University of Sydney, Sydney, NSW, Australia; 3Centre for Transplant and Renal Research, Westmead Hospital, Westmead, NSW, Australia.

    Aim: To evaluate the completeness of reporting of adverse events in randomized controlled trials (RCTs) of maintenance immunosuppression in kidney transplantation.Background: Side effects of maintenance…
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