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American Transplant Congress abstracts

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Articles tagged "Adverse effects"

  • 2015 American Transplant Congress

    Effect of Antibody Mediated Rejection on Long-Term Renal Allograft Function

    M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Historically we had poor understanding of chronic rejection attributing it to hypertension and non-compliance. However in the last decade we have begun to understand the…
  • 2015 American Transplant Congress

    De Novo Once-Daily Tacrolimus in Liver Transplantation: Long-Term Outcomes of a Single Center Cohort of 150 Patients

    M. Gastaca, A. Valdivieso, J. Bustamante, P. Ruiz, J. Fernandez, A. Ventoso, M. Testillano, I. Palomares, P. Salvador, M. Prieto, A. Matarranz, M. Suarez, J. Ortiz de Urbina.

    Liver Transplantation Unit, Cruces University Hospital. University of the Basque Country, Bilbao, Vizcaya, Spain.

    Purpose: To describe the long-term safety and efficacy profile of de novo once-daily tacrolimus (Tac QD) in orthotopic liver transplantation (OLT)Patients and methods: A retrospective…
  • 2015 American Transplant Congress

    Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection

    A. Lichvar,1 D. Deen,2 H. Johnson,1 J. Bonner,3 G. Bond,4 G. Costa,4 R. Cruz,4 K. Abu-Elmagd,5 R. Venkataramanan.6,7

    1Department of Pharmacy and Therapeutics, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Department of Pharmacy, Memorial University Medical Center, Savannah, GA; 3Northern Institute for Cancer Research at Newcastle University, Tyne and Wear, United Kingdom; 4Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; 5Center for Gut Rehabilitation and Transplantation, Cleveland Clinic, Cleveland, OH; 6Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; 7Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

    Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…
  • 2015 American Transplant Congress

    Impact of Machine Perfusion After Long Static Cold Storage On Delayed Graft Function Incidence and Duration and Time to Hospital Discharge

    A. Matos,1 M. Borrelli, Jr.,1 L. Moura Requiao,1 M. Nogueira, Jr.,1 L. Pertusier,1 G. Clarizia,1 P. Ongaro,1 S. Ximenes,1 M. Durao, Jr.,1,2 A. Pacheco-Silva.1,2

    1Transplantation, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; 2Medicine/Nephrology, Escola Paulista de Medicina, UNIFESP, Sao Paulo, Brazil.

    Our transplant center is not involved in organ harvesting and usually we receive a kidney for transplant with more then 20 hours of static cold…
  • 2015 American Transplant Congress

    Systematic Medical Record Review to Identify Safety Risks in Living Liver Donors

    B. Platt,5 D. Woods,5 R. Fisher,2 J. Guarrera,3 E. Pomfret,4 M. Simpson,4 A. Daud,1 T. Curtis,5 E. Reyes,5 E. Wymore,5 A. Skaro,1 D. Ladner.1

    1Northwestern University, Chicago, IL; 2Virginia Commonwealth University, Richmond, VA; 3Columbia University, New York, NY; 4Lahey Clinic, Boston, MA; 5CHS, Northwestern University, Chicago, IL.

    BACKGROUNDPrevention of adverse events (AEs) is important in Living Donor Liver Transplantation (LDLT), as these are healthy volunteers who undergo a major procedure with no…
  • 2015 American Transplant Congress

    ABCB1 Haplotypes, Sex, Calcineurin Inhibitors and Lipid Profiles Post-Renal Transplant

    C. Meaney,1,2 R. Venuto,3 D. Brazeau,4 J. Consiglio,5 L. Cooper,1 G. Wilding,5 K. Tornatore.1,2,3

    1NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY; 2School of Pharmacy, Buffalo, NY; 3Medicine, School of Medicine, Buffalo, NY; 4University of New England College of Pharmacy, Portland, ME; 5Biostatistics, School of Public Health, University at Buffalo, Buffalo, NY.

    Purpose: Hyperlipidemia is common in renal transplant recipients (RTR) during calcineurin inhibitor (CNI) immunosuppression. P-glycoprotein (P-gp) is an efflux transporter encoded by ABCB1 that modulates…
  • 2015 American Transplant Congress

    Risks for Readmission Post-Renal Transplant: A Co-Morbid Condition

    M. John, A. Smith, I. Dortonne, A. Paramesh, M. Killackey, B. Lee, R. Zhang, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Background: Recently CMS addressed “excessive” readmission rates with a punitive 5% cut in reimbursement. For decades renal transplantation has been highly regulated with published outcomes…
  • 2015 American Transplant Congress

    Medication Adherence and Treatment Satisfaction in Liver Transplant Recipients

    A. Albekairy,1 A. Alkatheri,2 N. Khalidi,2 K. Thiab,1 A. Jarab,2 A. Qandil,3 A. Alshaya,2 K. BinSaleh.2

    1Pharmaceutical Care Department, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia; 2Pharmacy Practice, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; 3Pharmaceutical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

    Background: Research has indicated that adherence to medication in patients with liver transplant is poor and considered as one of the main barriers to the…
  • 2015 American Transplant Congress

    Safety and Outcome of Ganciclovir-Resistant CMV Treated With Foscarnet: A Single Center Retrospective Study

    B. Pierce,4 C. Richardson,4 K. Cunningham,4 C. D'Agostino,4 C. Tseng,4 J. Brown,4 C. O'Brien,4 B. Ho,1,3,5 M. Ison.1,2,3

    1Department of Medicine, Northwestern Medicine, Chicago, IL; 2Division of Infectious Diseases, Northwestern Medicine, Chicago, IL; 3Division of Organ Transplantation, Northwestern Medicine, Chicago, IL; 4Pharmacy, Northwestern Medicine, Chicago, IL; 5Transplant Nephrology, Northwestern Medicine, Chicago, IL.

    Background: Infection with cytomegalovirus (CMV) is an important cause of morbidity and mortality following solid organ transplantation (SOT). Resistance can rarely develop via mutations in…
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