2019 American Transplant Congress » Poster Session A: Kidney Chronic Antibody Mediated Rejection

5:30pm-7:30pm

Automated Histology Lesion Interpretation in Kidney Transplant Biopsies Shows That Pathologists Often Deviate from Banff Guidelines

K. S. Madill-Thomsen¹, J. Reeve², G. Bohmig³, F. A. Eskandary⁴, A. Perkowska-Ptasinska⁵, M. Myslak⁶, P. F. Halloran and the INTERCOMEX Study Group¹

5:30pm-7:30pm

Back Signaling of HLA Class I Molecules and NK Cell Receptor Ligands in Renal Epithelial Cells Contributes to the Rejection-Specific Microenvironment

E. Chichelnitskiy¹, J. Egelkamp¹, K. Daemen¹, J. Keil¹, C. Neudörfl¹, J. Bräsen², J. Schmitz², H. Haller³, C. Blume⁴, C. Falk⁵

5:30pm-7:30pm

CD56+CD57+ Infiltrate is a Predominant Subset of Infiltrating Natural Killer Cell in Renal Transplant Biopsies with Antibody-Mediated Rejection

H. Jung¹, Y. Wee², J. Kim², M. Choi², J. Choi², H. Kwon², J. Jung², S. Kim³, Y. Cho⁴, Y. Park⁴, H. Go⁴, M. Han⁵, Y. Kim², D. Han², S. Shin²

5:30pm-7:30pm

Change in Estimated Glomerular Filtration Rate and Risk of Allograft Failure in Patients Diagnosed with Active Antibody-Mediated Rejection Following Kidney Transplantation

W. Irish¹, P. Nickerson², B. Astor³, E. Chong⁴, C. Wiebe², F. Moreso⁵, D. Seron⁵, M. Crespo⁵, L. Gache⁶, A. Djamali³

5:30pm-7:30pm

Clazakizumab (CLZ, Anti-IL-6 Monoclonal Antibody) Treatment of Patients (Pts) with Chronic Antibody-Mediated Rejection (cABMR) Reduces Total Immunoglobulin (Ig) and Anti-HLA IgG Antibody Levels

B. Shin, N. F. Ammerman, A. A. Vo, X. Zhang, S. C. Jordan, M. Toyoda

5:30pm-7:30pm

Increased Number of Intragraft FoxP3+ T Cells is Strongly Correlated with Decreased Graft Survival in Chronic Active Antibody Mediated Rejection

K. Sablik¹, K. Jordanova², M. Clahsen-van Groningen¹, M. Betjes¹

5:30pm-7:30pm

Lack of Response to Tocilizumab in Kidney Transplants with Chronic Antibody-Mediated Rejection

D. Kumar¹, F. Safavi¹, R. Sandhu¹, P. Halloran², I. Yakubu¹, M. Levy¹, I. Moinuddin¹, P. Kimball¹, L. Kamal¹, A. King¹, H. Massey¹, G. Gupta¹

5:30pm-7:30pm

Molecular Phenotype of Proliferative Arteriopathy in Kidney Grafts

A. Perkowska-Ptasinska¹, M. Ciszek¹, D. Deborska-Materkowska¹, A. Debska-Slizien², P. F. Halloran³, M. Myslak⁴

5:30pm-7:30pm

Multiple Non-HLA Antibodies Are Significantly Increased in Chronic Active Antibody Mediated Rejection

K. Sablik¹, E. Kamburova², D. Roelen³, H. Otten², M. Betjes¹

5:30pm-7:30pm

Natural Killer Cells Express Significantly More CD16 during Chronic Active Antibody Mediated Rejection Which is Not Caused by a Single Nucleotide Polymorphism within the CD16 Gene

K. Sablik, N. Litjens, A. Peeters, M. Clahsen-van Groningen, M. Klepper, M. Betjes

5:30pm-7:30pm

Significance of Histopathologic Features for Predicting Progression in Patients with Transplant Glomerulopathy

X. Li, J. Chen, D. Cheng, R. Wang, W. Wang, M. Zhang, F. Xu, J. Wen, Z. Tang

5:30pm-7:30pm

The Impact of Calcineurin Inhibitors on De Novo DSA in Primary Kidney Transplantation

T. Hiramitsu, T. Tomosugi, K. Futamura, M. Okada, M. Tsujita, T. Ichimori, N. Goto, S. Narumi, Y. Watarai

5:30pm-7:30pm

Validation of Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) in Renal Allograft Biopsies (Bx) of HLA-Sensitized Patients

H. Zhang¹, C. C. Nast², N. Ammerman³, A. A. Vo³, S. C. Jordan³, M. Toyoda¹