ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Aldosterone Acts Directly On T Cells, and Promotes Production of Inflammatory Cytokines

    J. Bagley, S. Begum, J. Iacomini.

    Department of Developmental, Molecular and Chemical Biolgy, Tufts University Medical School, Boston.

    Aldosterone is a mineralocorticoid hormone involved in the regulation of blood electrolyte concentration, blood pressure and blood volume. The primary receptor for aldosterone is the…
  • 2015 American Transplant Congress

    Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients

    M.-C. Lee,1,2 G.-J. Ho,1 Y.-C. Chen,1 B.-G. Hsu.2

    1Department of Surgery, Tzu Chi General Hospital, Hualien, Taiwan; 2Department of Medicine, School of Medicine Tzu Chi University, Hualien, Taiwan; 3Department of Medicine, Tzu Chi General Hospital, Hualien, Taiwan.

    Objective: Recent studies found osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to…
  • 2015 American Transplant Congress

    Cultural Domains Affecting Organ Donation in Indian Country

    T. Bongiovanni,1,3,4 J. Rawlings,2 J. Trompeta,3 M. Nunez-Smith.1

    1Dept of Surgery, UCSF, San Francisco; 2Tribal Council, New Haven, CT; 3Robert Wood Johnson Foundation, Yale School of Medicine, New Haven, CT; 4Department of Veterans Affairs, West Haven.

    Background: The prevalence of end-stage renal disease is 3.5 times greater among the >2.5 million Native Americans or Alaskan Natives (NAs) in the US than…
  • 2015 American Transplant Congress

    Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function

    E. Ablorsu,1 S. Zouwail,2 P. Laftsidis,1 B. Cook,1 L. Szabo.1

    1Cardiff Transplant Unit, University Hospital for Wales, Cardiff, United Kingdom; 2The Medical Biochemistry and Immunology Department, University Hospital for Wales, Cardiff, United Kingdom.

    Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…
  • 2015 American Transplant Congress

    The Impact of FcγRIIA, FcγRIIIA and C1QA Genes Polymorphism On Infectious Complications Following Renal Transplantation

    L. Das, Y. Tanaka, S. Verma, S. Shimizu, K. Ide, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    AIM- Infectious complication is the leading cause of graft and patient loss after renal transplantation (RT). Under immunosuppressive condition when acquired immunity is suppressed, components…
  • 2015 American Transplant Congress

    Perfusion Disturbances and Local Infarctions After Experimental Kidney Transplantation Corralte With the Duration of Cold Ischemia Time

    S. Rong,1 R. Chen,1 M. Meier,4 B. Hensen,2 H. Haller,1 K. Hueper,2 F. Gueler.1

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Radiology, Hannover Medical School, Hannover, Germany; 3Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada; 4Imaging Center, Hannover Medical School, Hannover, Germany.

    Background: Kidney transplantation in mice is challenging but offers good translational models to study mechanisms of disease. In this study allogenic and isogenic kidney transplantation…
  • 2015 American Transplant Congress

    Steroid-Free Quadruple Induction Regimen With Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Reduces Incidence of Biopsy-Proven Acute Rejection and Toxicity Profile Compared to the Standard Triple Regimen

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant clinical problem even with low exposure regimens. On the other hand, CNI-free…
  • 2015 American Transplant Congress

    Prospective Study of a Steroid Free, Low Dose Tacrolimus and Everolimus Combination Regimen in Kidney Transplant

    A. Shetty,1 J. Leventhal,1 O. Traitanon,1 A. Alvarado,1 V. Mas,2 J. Mathew,1 E. Tantisattamo,1 L. Gallon.1

    1Nephrology/Comprehensive Transplant, Northwestern University, Chicago; 2Surgery, Virginia Commonwealth University, Richmond.

    Calcineurin(CNI) based therapy is the cornerstone of immunosuppresion(IS) after kidney transplant. However chronic nephrotoxicity from CNI as been implicated in post-transplant renal dysfunction. We hypothesized…
  • 2015 American Transplant Congress

    Post Hoc Subgroup Analysis of ZEUS: Outcome on Renal Function, Efficacy and Safety in Living-Donor Kidney Transplant Recipients After Conversion from a Calcineurin Inhibitor to an Everolimus Based Regimen: 5 Year Follow-Up Data

    F. Lehner,1 K. Budde,1 R. Wuethrich,2 P. Reinke,1 W. Arns,1 A. Muehlfeld,1 U. Eisenberger,1 R. Stahl,1 K. Heller,1 O. Witzke,1 B. Suwelack,1 H. Wolters,1 I. Hauser,1 M. Porstner,3 C. Sommerer.1

    1ZEUS Study Group, Germany; 2ZEUS Study Group, Switzerland; 3Novartis, Pharma, Germany.

    Background: To study renal function and patient outcome after 5 years in living donation subgroup of kidney de novo transplant recipients after conversion to an…
  • 2015 American Transplant Congress

    Plasma Cell Infiltration: General Overview of Clinical and Pathological Correlations in Renal Transplantation

    C. Nihei, F. Lemos, D. David, P. Souza, F. de Paula, W. Nahas, E. David-Neto.

    Transplantation Service, Hospital das Clinicas-University of São Paulo, São Paulo, SP, Brazil.

    Background and Objective: Plasma cells are known as the final effectors of humoral immune response. Their significance and clinical outcomes are still controversial in kidney…
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