2015 American Transplant Congress
Endovascular Salvage of a Pancreas Allograft Having Developed a Large AV Fistula and Aneurysm
1Surgery, Mayo Clinic, Phoenix, AZ; 2Radiology, Mayo Clinic, Phoenix, AZ.
We present an unusual case of a late, large pancreas allograft arteriovenous fistula and aneurysm rescued from threatened rupture or need for transplant pancreatectomy by…2015 American Transplant Congress
Application of the Clavien Classification of Surgical Complications to Robotic Kidney Transplantation
Surgery, Transplant Division, University of Illinois Hospital and Health Sciences, Chicago, IL.
INTRODUCTIONThe Clavien-Dindo Classification of complications after a surgical procedure is an objective measure of outcomes and serves as a comparison tool to evaluate procedure safety…2015 American Transplant Congress
DNA Methylation of the IFNγ Promoter in CD8+ T Cell Subsets Is Modulated by CMV Infection but not by Alloreactivity in Kidney Transplantation Patients
Introduction DNA methylation plays a critical role in the function of cells, including cells of the immune system. Little is known about the methylation status…2015 American Transplant Congress
Frequencies of CD4+25hiFoxp3+ T Cells in Long-Term Follow-Up of Sirolimus-Converted Kidney Transplant Recipients
Background: Tacrolimus(TAC) and Sirolimus(SRL) are commonly used immunosuppressive drugs in kidney transplantation. SRL has been shown to induce the expansion of regulatory T cells in…2015 American Transplant Congress
Development and Validation of a Genotype Guided Tacrolimus Dosing Equation for African American (AA) Kidney Transplant Recipients
Tacrolimus (tac) has a strong exposure-response relationship with high inter-individual variability in troughs and dose. Tac dose requirements for AA patients are higher than Caucasians,…2015 American Transplant Congress
CMV prevalence in Mauritian and Indonesian Cynomolgus Macaques: Significance in Transplantation and CMV Disease Models
Despite the finding that most macaques express high serologic titers of anti-CMV antibody, susceptibility to disease appears to be variable post-transplant. This observation led us…2015 American Transplant Congress
T Cell Specific Up Regulation of Nrf2 Regulated Antioxidant Response Protects from Kidney Ischemia Reperfusion Injury in Mice
Background: T lymphocytes mediate important pathophysiological roles during ischemia reperfusion injury (IRI). Transcription factor Nrf2 is protective during experimental kidney IRI and thought to be…2015 American Transplant Congress
Cross-Linking of MHC Class I Induces Unique Transcriptional Profiles Associated With Regulation of Both T and B Cells That Precedes Induction of Allo- and Auto-Immunity Leading to Obliterative Airway Disease
Surgery, Washington Univ Sch of Med, St. Louis, MO.
Background: Incidences of chronic rejection, bronchiolitis obliterans syndrome (BOS), remain a major challenge to lung transplantation and development of allo- and auto-immunity has been proposed…2015 American Transplant Congress
Pregnancy After Renal Transplantation: Unfavorable Outcomes in Sensitized Patients
Einstein/Montefiore Transplant Center, Bronx.
Background: The objective of our study was to describe pregnancy and allograft outcomes in sensitized kidney recipients in a predominantly Hispanic and African-American population.Methods: This…2015 American Transplant Congress
Intermittent High Dose Intravenous Immunoglobulin as Treatment for Donor Specific Antibodies in Renal Transplant Recipients
Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population have indicated…
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