2015 American Transplant Congress
Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection
The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…2015 American Transplant Congress
The Impact of a Desensitization Protocol Using Plasmapheresis and Intravenous Immunoglobulin On Graft Outcome in Kidney Recipients With Donor Specific Anti-HLA Antibodies
Hospital Geral de Fortaleza, Fortaleza, Brazil.
Introduction: Kidney transplantation in patients with donor-specific anti-HLA antibodies (DSA) has been associated with a worse prognosis. The high cost, infectious complications and conflicting results…2015 American Transplant Congress
Robotic Kidney Transplantation in Obese Recipients Can Lead to Superior Outcomes in Terms of Wound Infection and Graft Survival
Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.
IntroductionTraditionally kidney transplantation (KT) in obese recipients has been associated with high rates of surgical site infections (SSI). We hypothesize that robotic kidney transplantation (RKT)…2015 American Transplant Congress
Optimal Induction Therapy (IT) in Pancreas After Kidney Transplantation (PAK) According to Type of Kidney (kd) Donor and Patient Risk – A Registry Analysis
1University of Arizona, Tucson, AZ; 2University of Arizona, Tucson, AZ.
Purpose: Best IT in PAK recipients (rec) according to type of kd donor (LD vs. DD) and rec risk has not been determined.Methods: Using the…2015 American Transplant Congress
Tolerance to Graft A-Antigens Following ABO-Incompatible Heart Transplantation (HTx) in a Blood Group A-Transgenic Mouse Model
Purpose: ABOi HTx can be performed safely in infants when ABO antibody (Ab) levels are low or absent. Following ABOi HTx, immune tolerance develops to…2015 American Transplant Congress
The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients
Urology, Tokyo Women's Medical University, Tokyo, Japan.
We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…2015 American Transplant Congress
Structure/Function Insights Into Treg Biology: Hdac11 Is a Foxp3 Deacetylase Whose Targeting Promotes and Stabilizes Foxp3 Expression and Leads to Long-Term Allograft Survival
1CHOP & UPenn, Philadelphia; 2Uni of Illinois at Chicago, Chicago.
Aim: There are huge scientific, economic and practical advantages in developing pharmacologic approaches to enhance Foxp3+ Treg function in allograft recipients versus simply injecting enormous…2015 American Transplant Congress
Preemptive Deceased Donor Transplant With Kidney Donor Profile Index Scores Greater Than 85 Not Associated With a Survival Benefit
University of Virginia, Charlottesville, VA.
Preemptively listed candidates for kidney transplant are a unique patient population with regard to marginal quality kidney acceptance as they are not yet dialysis dependent.…2015 American Transplant Congress
Clinical and Pathologic Predictors of Response to Belatacept Conversion
Columbia Universtiy, New York.
INTRO: Calcineurin inhibitors have improved kidney transplant and recipient survival, their use has significant nephrotoxicity. Belatacept is a recently approved immunosuppressant that is not nephrotoxic…2015 American Transplant Congress
T Cell C5a Receptor (C5aR) Signaling Regulates T Follicular Helper Cell (Tfh) Induction
Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Tfh cells, in part via IL-6 dependent production of IL-21, are specialized providers of B cell help. Extending previous work in which we showed that…
American Transplant Congress abstracts