2015 American Transplant Congress
Blood Gene Expression Profiling in a Randomized Controlled Trial of rATG Vs. IL2RA Induction Reveals the Differences in Immune Impact and Mechanisms
1MUSC, Charleston, SC; 2Scripps Research Institute, La Jolla, CA.
We performed global gene expression profiling using microarrays on samples from a prospective, RCT designed to study the safety & efficacy of induction with antithymocyte…2015 American Transplant Congress
Associations of Pre-Transplant Prescription Narcotic Use With Clinical Complications After Kidney Transplantation
Background: Associations of narcotic use before kidney transplantation with post-transplant clinical outcomes are not well described.Methods: We performed a retrospective analysis of linked national registry…2015 American Transplant Congress
Quality of Life, Financial, and Mental Health Outcomes for Individuals Turned Down for Live Kidney Donation
1UPenn, Philadelphia, PA; 2Harvard, Cambridge, MA.
Introduction: Individuals considering live kidney donation should have a thorough understanding of the risks and benefits. Regulations focus exclusively on donation risks. However, no data…2015 American Transplant Congress
Distinct Role of Complement Receptors C5L2 and C5aR in Acute Kidney Injury and Renal Fibrosis
ObjectiveAcute kidney injury (AKI) is a relevant complication in solid organ transplantation with incidence rates of ∼50-75 % after lung- and heart transplantation. In addition,…2015 American Transplant Congress
Intrapatient Variability of Tacrolimus Trough Levels and Outpatient Clinic Non-Attendance Rates Predict Poor Renal Allograft Survival
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication post renal transplant is an importnat risk factor for rejection and graft loss. In this study we assess the association between…2015 American Transplant Congress
Diminished Survival After Simultaneous Liver-Kidney Transplant With Increasing Kidney Donor Profile Index Score
Transplant Center, University of Texas Health Science Center, San Antonio, TX.
BACKGROUND: Since the introduction of MELD, the number of simultaneous liver-kidney (SLK) transplants has greatly increased. Renal failure after liver transplant is associated with a…2015 American Transplant Congress
Recipient Immunity to Murine Cytomegalovirus Influences Natural Killer Cell Responses in Infected Renal Allografts
BACKGROUND: Human cytomegalovirus (CMV) is associated epidemiologically with renal allograft loss, but the impact of recipient CMV immunity upon graft survival is unclear. Natural killer…2015 American Transplant Congress
The Role of Quantitative Assay of Urinary Decoy Cells as a Screening and Follow-Up Tool in Renal Transplant Recipients With Polyomavirus BK Infection
Polyomavirus BK nephropathy (BKVN) is an important infectious complication in kidney transplant patients. Urinary cytology is effective for early diagnosis of BKVN. However, quantitative assay…2015 American Transplant Congress
Molecular Features of Isolated Arteriolar Hyalinosis in Renal Transplant Biopsies
Background: Arteriolar hyalinosis (ah) is characterized by deposition of hyaline material in the vascular wall that may be caused by different insults including diabetes, hypertension…2015 American Transplant Congress
Membranoproliferative Glomerulonephritis After Kidney Transplantation: A Single Center Experience
The Johns Hopkins University, Baltimore, MD.
Introduction: Membranoproliferative glomerulonephritis (MPGN) is a glomerular disease that frequently leads to ESRD requiring dialysis or kidney transplantation. MPGN recurrence after transplant (rMPGN) often happens…
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