ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    A Tool to Estimate Probability of Outcomes on the Liver Transplant Waiting List

    A. Hart,1,2 D. Schladt,1 J. Zeglin,1 N. Salkowski,1 S. Leppke,1 W. Kim,1,3 J. Lake,1,4 A. Israni,1 B. Kasiske,1 J. Snyder.1

    1Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; 2Medicine, Hennepin County Medical Center, Minneapolis, MN; 3School of Medicine, Stanford University, Stanford, CA; 4Medicine, University of Minnesota, Minneapolis, MN.

    The probability of liver transplant (LTX) and death for candidates varies by donation service area (DSA), making it difficult for candidates to understand the likely…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Has Been Safe in the United Kingdom and Achieves Long-Term Steroid Avoidance in More Than 80% of Low Risk Renal Transplant Recipients

    A. Seitz,1 M. Robb,3 S. Balasubramanian,1 A. McLean,2 D. Taube,2 R. Johnson,3 R. Baker.1

    1Renal Unit, St. James's Hospital, Leeds, United Kingdom; 2West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom; 3Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom.

    Introduction: The use of alemtuzumab as an induction agent for renal transplantation is increasing in the UK. There is some evidence to suggest that this…
  • 2015 American Transplant Congress

    Focal Segmental Glomerulosclerosis Recurrence in Renal Transplant Recipients Treated With Belatacept

    W. Kitchens,1 A. Farris,2 S. Pastan,1 T. Pearson,1 C. Larsen,1 A. Adams.1

    1Emory Transplant Center, Atlanta, GA; 2Department of Pathology, Emory University Hospital, Atlanta, GA.

    Introduction: Focal segmental glomerulosclerosis (FSGS) is a cause of end-stage renal failure that frequently recurs following renal transplant, often leading to early allograft loss. A…
  • 2015 American Transplant Congress

    Virus Induced CD28 Down-Regulation as a Potential Driver of Costimulation Blockade Resistant Rejection

    D. Mou,1 J. Espinosa,1 L. Stempora,2 J. Kwun,2 N. Iwakoshi,1 A. Kirk.2

    1Surgery, Emory University, Atlanta, GA; 2Surgery, Duke University, Durham, NC.

    Belatacept, a B7-specific fusion protein, blocks CD28-B7 costimulation and prevents kidney allograft rejection. However, it is ineffective in a sizable minority of patients. Although T…
  • 2015 American Transplant Congress

    Norovirus Infection in Renal Transplant Recipients – Clinical Severity and Genotype Identification

    J. Roodnat,1 Y. Rakké,1 J. Beek van,3 M. Koopmans,2 M. Betjes,1 W. Weimar,1 M. Beersma.2

    1Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; 2Department of Viroscience, Erasmus Medical Centre, Rotterdam, Netherlands; 3National Institute for Public Health and the Environment, Bilthoven, Netherlands.

    Introduction: Norovirus (NoV) is increasingly recognized as causative agent of gastro-enteritis in renal transplant recipients.Methods: We performed a retrospective study (2003-2012) to investigate the clinical…
  • 2015 American Transplant Congress

    Dramatic Improvements in Racial Disparities in Kidney Transplant Outcomes in the US

    T. Purnell,1 X. Luo,1 L. Kucirka,1 L. Cooper,1 A. Massie,1 D. Crews,1 L. Boulware,2 D. Segev.1

    1Johns Hopkins, Baltimore; 2Duke University, Durham.

    Earlier studies reported inferior graft survival in black transplant recipients. We examined 20-year trends in outcomes to determine whether racial disparities improved over time. METHODS:…
  • 2015 American Transplant Congress

    Effector T Cell Migration to Pancreatic Islet Allografts Is Dependent On Donor Antigen Recognition and Not Gαi Chemokine Signaling

    Q. Zhang, H. Dai, Q. Zeng, A. Williams, M. Oberbarnscheidt, F. Lakkis.

    Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA.

    Infiltration of the graft with host effector T cells after transplantation is a key step in the pathogenesis of both acute and chronic rejection. Recent…
  • 2015 American Transplant Congress

    Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?

    S. Constantinescu,1,2 L. Coscia,2 D. Armenti,2 P. Axelrod,1 M. Ghanta,1 S. Rao,1 M. Moritz.2,3

    1Temple University School of Medicine, Philadelphia; 2National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; 3Lehigh Valley Health Network, Allentown.

    The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…
  • 2015 American Transplant Congress

    Impact of Pretransplant Sarcopenia and Sequential Changes in Sarcopenic Parameters After Living Donor Liver Transplantation

    T. Kaido,1 Y. Tamai,2 K. Ogawa,1 Y. Fujimoto,1 A. Mori,1 H. Okajima,1 N. Inagaki,2 S. Uemoto.1

    1Hepato-Biliary-Pancreatic and Transplant Surgery, Kyoto University, Kyoto, Japan; 2Metabolism and Clinical Nutrition, Kyoto University Hospital, Kyoto, Japan.

    The present study investigated the impact of pretransplant sarcopenia on survival and sequential changes in sarcopenic parameters in patients undergoing living donor liver transplantation (LDLT).…
  • 2015 American Transplant Congress

    Multivisceral Transplantation Without an Ostomy – Experience With 15 Patients

    T. Beduschi, J. Garcia, S. Nishida, A. Tekin, J. Fan, G. Selvaggi, P. Ruiz, R. Vianna.

    Miami Transplant Institute, University of Miami Miller School of Medicine, Miami, FL.

    Introduction: Despite improvement in short term outcomes, rejection remains a main cause of graft and patient loss in intestinal transplant. A temporary ostomy to assess…
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