Am J Transplant, Volume 5, Suppl 3 Archives - Page 160 of 170 - ATC Abstracts

2015 American Transplant Congress
DEPTOR Is Expressed in CD4+ T Cells and Modulates Effector Responses and Allograft Rejection
J. Wedel, S. Bruneau, K. Liu, N. Kochupurakkal, M. Laplante, D. Briscoe.
Transplant Research Program, Boston Children's Hospital, Boston, MA.
DEPTOR is an evolutionarily conserved, first-in-kind cell intrinsic factor with potential to regulate the activity of multiple intracellular signaling pathways. However, its biology in T…
2015 American Transplant Congress
Prediction of Acute Antibody Mediated Rejection in Antibody Incompatible Renal Transplantation Using Machine Learning for Wide Data
T. Shaikhina,¹ N. Khovanova,¹ S. Daga,^1,3 N. Krishnan,² D. Lowe,³ D. Mitchell,¹ D. Briggs,² R. Higgins.³
¹University of Warwick, Coventry, United Kingdom; ²NHS Blood and Transplant, Birmingham, United Kingdom; ³University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.
The dynamic field of renal transplantation is characterised by limited access to data, the high cost of equipment and underlying complexity of immunological responses to…
2015 American Transplant Congress
Efficacy of Low Dose Chemoprophylaxis for Coccidioidomycosis Infection in Liver Transplantation Recipients
R. El Ramahi,² S. Habib,¹ S. Rosen,³ S. Farran,³ C. Walker,³ J. Shubeilat,⁴ S. Yost,⁵ O. McCotter,⁶ M. Cassal,⁶ A. Rana,⁷ T. Boyer,¹ T. Zangeneh.²
¹Liver Research Institute, Divisions of Gastroenterology, Hepatology and Transplantation, Department of Medicine, University of Arizona, Tucson, AZ; ²Division of Infectious Disease, Department of Medicine, University of Arizona, Tucson, AZ; ³Internal Medicine Residency Program, Department of Medicine, University of Arizona, Tucson, AZ; ⁴Division of Infectious Disease, Department of Medicine, University of Massachusetts, Worcester, MA; ⁵Division of Transplantation, School of Pharmacy, University of Arizona, Tucson, AZ; ⁶Office of Border Health, Arizona Department of Health Services, Tucson, AZ; ⁷Division of Transplantation, Department of Surgery, University of Arizona, Tucson, AZ.
Introduction:Coccidioidomycosis(CM) infection rate of 6.9% has been reported in solid organ transplantation recipients living in endemic Southwestern U.S.Aim:Assess the risk of CM infection in liver…
2015 American Transplant Congress
MicroRNAs in Kidney Graft Preservation Fluid as Novel Biomarkers for Delayed Graft Function
L. Ooms, H. Roest, S. van den Hoek, R. de Bruin, J. IJzermans, L. van der Laan, F. Dor.
Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands.
Introduction: Delayed graft function is a common complication after deceased donor kidney transplantation (KT), which affects both short and long-term outcome. Currently available biomarkers in…
2015 American Transplant Congress
Monitoring Intracellular Tacrolimus Concentration in Kidney Transplant Recipients With Stable Graft Function
E. Bae,¹ S. Han,¹ S. Yang,² J. Park,¹ H. Lee,¹ J. Lee,³ D. Kim,¹ Y. Kim.¹
¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ²Kidney Research Institute, Seoul National University, Seoul, Korea; ³Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Background: Monitoring the intracellular concentration of immunosuppressive agents can be promising to improve and individualize clinical practice in patients receiving transplantation. However, this issue remains…
2015 American Transplant Congress
Outcomes of HIV+ Liver Transplant Recipients Compared to HCV+ or HIV+/HCV+ Co-Infected Recipients: The “Real World” Experience
D. Sawinski,¹ G. David,² E. Blumberg,³ P. Abt,⁴ R. Bloom,¹ K. Forde.²
¹Renal Division, Univ. of Penn, Philadelphia, PA; ²Gastroenterology Division, Univ. of Penn, Philadelphia, PA; ³Infectious Disease, Univ. of Penn, Philadelphia, PA; ⁴Surgery, Univ of Penn, Philadelphia, PA.
End stage liver disease is a frequent cause of mortality in patients with HIV. Though demonstrated in the NIH observational trial, the effectiveness of LT…
2015 American Transplant Congress
Identifying the “Operational Tolerant” Pediatric Liver Transplant Recipient by Cytometry by Time-of-Flight
A. Lau,^1,2 M. Vitalone,¹ K. Haas,³ T. Shawler,¹ C. Esquivel,¹ O. Martinez,¹ R. Castillo,³ S. Krams.¹
¹Surgery, Division of Abdominal Transplantation, Stanford University, Stanford, CA; ²Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, San Francisco, CA; ³Pediatrics, Div. Gastroenterology, Hepatology, and Nutrition, Stanford University, Stanford, CA.
Liver allografts are known to be well tolerated and indeed, some recipients of liver allografts retain stable graft function in the absence of immunosuppression. The…
2015 American Transplant Congress
Role of Innate Immune Cells in Chronic Allograft Loss and Novel Strategies to Target Them
C. Wu,^1,2 P. Zhao,¹ W. Liu,¹ X. Xiao,¹ X. Shi,¹ Y. Peng,¹ M. Kloc,¹ X. He,² M. Ghobrial,¹ X. Li.¹
¹Center for Immunobiology and Transplantation Research, Houston Methodist Hospital and Houston Methodist Research Institute, Houston, TX; ²Organ Transplant Center, 1st Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Despite remarkable improvements in short term transplant survival, the long-term outcome of allografts remains poor in the clinic, and most transplants are eventually lost due…
2015 American Transplant Congress
A Tool to Estimate Probability of Outcomes on the Liver Transplant Waiting List
A. Hart,^1,2 D. Schladt,¹ J. Zeglin,¹ N. Salkowski,¹ S. Leppke,¹ W. Kim,^1,3 J. Lake,^1,4 A. Israni,¹ B. Kasiske,¹ J. Snyder.¹
¹Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; ²Medicine, Hennepin County Medical Center, Minneapolis, MN; ³School of Medicine, Stanford University, Stanford, CA; ⁴Medicine, University of Minnesota, Minneapolis, MN.
The probability of liver transplant (LTX) and death for candidates varies by donation service area (DSA), making it difficult for candidates to understand the likely…
2015 American Transplant Congress
Alemtuzumab Induction Has Been Safe in the United Kingdom and Achieves Long-Term Steroid Avoidance in More Than 80% of Low Risk Renal Transplant Recipients
A. Seitz,¹ M. Robb,³ S. Balasubramanian,¹ A. McLean,² D. Taube,² R. Johnson,³ R. Baker.¹
¹Renal Unit, St. James's Hospital, Leeds, United Kingdom; ²West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom; ³Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom.
Introduction: The use of alemtuzumab as an induction agent for renal transplantation is increasing in the UK. There is some evidence to suggest that this…