ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Longterm Outcome in Pancreas Grafts After Polyomavirus Infection in Combined Kidney-Pancreas Transplants: A Single Center Report

    C. Boesmueller,1 C. Margreiter,1 M. Rudnicki,2 R. Oellinger,3 S. Schneeberger,1 M. Maglione.1

    1Transplant Surgery, University Hospital, Innsbruck, Austria; 2Nephrology, University Hospital, Innsbruck, Austria; 3General Surgery, University Charité Virchow Hospital, Berlin, Germany.

    Purpose: We retrospectively analyzed the longterm survival and function in pancreas grafts after reduction of immunosuppression due to polyomavirus infection in simultaneous pancreas kidney transplants…
  • 2015 American Transplant Congress

    Ligation of the Native Ureter for Treatment of Urinary Fistula in Kidney Transplantation: Is It Safe?

    C. Batagello, K. Yamaçake, R. Falci, H. Kanashiro, R. Kato, G. Ebaid, A. Piovesan, W. Nahas.

    Division of Urology, Renal Transplantation Unit, University of Sao Paulo, Sao Paulo, Brazil.

    Purpose: Urinary fistula and ureteral stenosis occur respectively in 2-5% and 2-7.5% after kidney transplantation. Within the different causes of stenosis and fistula after kidney…
  • 2015 American Transplant Congress

    Systemic and Local NK and Regulatory Cell Phenotypes and mTori-Induced Tumor-Specific Effector T-Cell Responses Are Key Players Favoring the Development of Squamous Cell Skin Carcinoma Among Kidney Transplant Patients

    E. Crespo,1 M. Lucia,1 L. Fernandez,3 E. Melilli,2 S. Luque,1 R. Lauzurica,3 J. Cruzado,1,2 J. Torras,1,2 J. Grinyó,1,2 O. Bestard.1,2

    1Nephrology Laboratory, IDIBELL, Barcelona, Spain; 2Nephrology Department and Renal Transplant Unit, Bellvitge University Hospital, Barcelona, Spain; 3Kidney Transplant Unit, Germans Trias i Pujol University Hospital, Badalona, Spain.

    Renal transplant patients are at higher risk of developing squamous cell carcinoma (SCC). Immunosuppressive agents promote an imbalance between effector and regulatory tumor-specific immune responses,…
  • 2015 American Transplant Congress

    Does Switching Predict Conversion: IgM De Novo Donor Specific HLA Antibodies Class Switch to IgG in Subclinical Antibody Mediated Rejection in Heart Transplant Recipients

    M. Askar,1 R. Rodriguez,1 L. Klingman,1 D. Thomas,1 A. Zhang,1 H. Morf,2 N. Hamon,1 N. Moazami,1 E. Hsich,1 D. Taylor,1 R. Starling,1 C. Tan.1

    1Cleveland Clinic, Cleveland; 2School of Medicine, Leipzig University, Leipzig, Germany.

    Background: Concomitant C4d and C3d detection in heart biopsies correlates with circulating DSA and graft dysfunction. Detection of C4d only in surveillance biopsies is not…
  • 2015 American Transplant Congress

    Evaluation of Natural Killer Cell Activation by NK Cell-Specific Interferon-Gamma-Releasing Assay

    J. Ryu,1 K. Park,1 Y. Kim,2 E.-J. Oh.2

    1Department of Biomedical Science, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea; 2Laboratory Medicine, Seoul St. Mary's Hospital, the Catholic University of Korea, Seoul, Republic of Korea.

    Introduction: Although NK cell activity (NKA) has a variety of measuring markers including chromiun release assay and flowcytometry-based cytolysis, limitations such as radioactivity and lack…
  • 2015 American Transplant Congress

    Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients

    J. Bank,1 M. Reinders,1 M. Mallat,1 N. Schlagwein,1 S. van der Kooij,1 D. van Gijlswijk,1 I. Bajema,2 C. van Kooten,1 H. de Fijter.1

    1Nephrology, LUMC, Leiden, Netherlands; 2Pathology, LUMC, Leiden, Netherlands.

    Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…
  • 2015 American Transplant Congress

    2B4 Expression on Human CD4+ Memory T Cells Is Associated With Functional Impairment

    C. Chen, S. Laurie, J. Lyons, C. Coopersmith, M. Ford.

    Emory Transplant Center, Emory University, Atlata, GA.

    The SLAM family receptor 2B4 is expressed primarily on NK cells and memory CD8+ T cells. In prior studies, we found that 2B4 was upregulated…
  • 2015 American Transplant Congress

    Lymphatic Endothelium Uniquely Enhances T Cell Migration to S1P

    C. Brinkman, Y. Xiong, J. Bromberg.

    University of Maryland, Baltimore, MD.

    Introduction: Sphingosine-1-phosphate (S1P) is a signaling sphingolipid that regulates cell egress from lymphoid and non-lymphoid tissues. While S1P has been described as a chemoattractant, its…
  • 2015 American Transplant Congress

    Living Donor Gifted Lithiasis: Outcomes in Kidney Transplant Recipients

    M. Mujtaba, C. Sundaram, M. Yaqub, T. Taber, J. Powelson, S. Doshi, A. Sharfuddin.

    Indiana University, Indianapolis.

    BACKGROUND: The presence of kidney stones has been a relative contraindication for living donation. The long term outcomes and safety of kidney transplant recipients of…
  • 2015 American Transplant Congress

    U.S. Population Characteristics Impacting Rates of Organ Donation

    B. Schleich,1 S. Yoon,1 M. Khasawneh,1 K. Srihari,1 W. Tajik,2 H. Irving.2

    1Systems Science and Industrial Engineering, State University of New York at Binghamton, Binghamton, NY; 2New York Organ Donor Network, New York, NY.

    Many studies have assessed the impact of factors on organ donation, but have been limited to a few thousand subjects or less. The multicultural composition…
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