2015 American Transplant Congress
Comparison of Creatinine Based Estimated Glomerular Filtration Rate (eGFR) and Iothalamate-Measured GFR (mGFR) Following Simultaneous Pancreas – Kidney Transplantation
University Hospitals Case Medical Center, Cleveland.
Objective: Creatinine based eGFR equations may overestimate the true GFR in simulataneous pancreas-kidney (SPK) transplant patients, owing to the low lean body mass in these…2015 American Transplant Congress
Right-Sided Kidney Transplants Are Associated With Early Graft Failure in the Setting of Delayed Graft Function
Yale University, New Haven, CT.
Anatomical differences between right and left kidneys may affect transplant outcomes. We sought to determine if the right kidney (RK) tends to have worse graft…2015 American Transplant Congress
A Primary Cytomegalovirus Infection Post-Transplantation Has a Significant Impact on Circulating T Cells and Renal Allograft Function
Study's purpose: Cytomegalovirus (CMV)-infection may profoundly affect the peripheral T-cell compartment and is associated with T-cell ageing and generation of cytotoxic CD4+CD28null T cells. We…2015 American Transplant Congress
Elderly ESRD Patients Have a Significantly Narrowed T-Cell Receptor Repertoire Diversity
IntroductionA diverse T-cell receptor (TCR) repertoire is central to effective T-cell mediated immune responses to foreign antigens. Patients suffering from end stage renal disease (ESRD)…2015 American Transplant Congress
CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures
Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…2015 American Transplant Congress
Operational Tolerance in Kidney Transplantation: Results of a Europe-Wide Survey
BACKGROUND: Operational Tolerance (opTOL) is deemed to be extremely rare in kidney transplantation. We launched a Europe-wide survey to assess the frequency of opTOL.METHODS: 18…2015 American Transplant Congress
OX40 Gene: A Potential Target for the Care of Chronic T-Cell Mediated Rejection (TCMR)
Introduction:TCMR is characterized by the reduction of vessel lumen with marked intimal thickening, fibrous hyperplasia and a strong component of leukocyte infiltrate. Aim of our…2015 American Transplant Congress
Characterization of a Nude Mouse Model of Allosensitization Conditioned by Adoptive Transfer of Follicular T Helper Cells
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background Follicular T helper (Tfh) cells play a critical role in follicular B cell activation and maturation during antibody responses to allograft. Here we report…2015 American Transplant Congress
Temporal Increase in the Incidence of Post-Transplantation Lymphoproliferative Disorder in Adult Renal Transplant Recipients: Analysis of 2 US Insurance Administrative Claims Databases
Bristol-Myers Squibb Company, Princeton, NJ.
Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after kidney transplant. In a prior analysis using Medicare claims database from 1995 to 2003, the…2015 American Transplant Congress
HLA-DR Matching Improves Immunologic Outcomes in Elderly Kidney Transplant Recipients
Nephrology, Charité Universitätsmedizin Berlin, Berlin, Germany.
BACKGROUND: The Eurotransplant senior program (ESP) neglects HLA matching for elderly (>65y) KTR. Only few data exist regarding the influence of HLA-DR-matching on immunologic outcomes.PATIENTS…
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