ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Lipid Profiles Over 2 Years Follow-Up in De Novo Kidney Transplant Recipients Randomized to Once-Daily MeltDose® Tacrolimus (Envarsus® XR) Vs. Twice-Daily Tacrolimus (Prograf®): Results from a Phase 3, Double-Blind, Double-Dummy, Multicenter Trial

    S. Mulgaonkar, O. Pankewycz, S. Steinberg.

    St. Barnabas Medical Center, Livingston; Erie County Medical Center, Buffalo; California Institute of Renal Research, San Diego.

    Cardiovascular disease (CVD) is a leading cause of death in kidney transplant recipients (KTR). Focusing on modifiable CVD risk factors is key to decreasing CVD-related…
  • 2015 American Transplant Congress

    In Pre-Implantation Biopsies Expression of Micro RNAs Is Not a Good Surrogate for Established mRNA Markers of Kidney Injury

    K. Famulski,1 S. Niederhaus,2 J. Reeve,1 J. Bromberg,2 P. Halloran.1

    1University of Alberta, Edmonton, Canada; 2University of Marlyland, Baltimore.

    Kidneys from brain dead donors>50 years old are often discarded based on conventional (clinical and histologic) criteria, despite their poor predictive value for subsequent performance…
  • 2015 American Transplant Congress

    Increased Late Graft Loss in Kidney Recipients With Serum Sickness Disease Following Anti-Thymocyte Globulin Induction: Relation With an Anti-Neu5Gc Response

    A. Salama,1,2 G. Couvrat-Desvergnes,1 M. Lorent,1,3 G. Evanno,1 L. Le Berre,1 P. Hruba,4 P. Vesely,5 P. Guerif,1 A. Nicot,1 J.-M. Bach,6 Y. Foucher,1,3 S. Brouard,1 S. Castagnet,7 O. Viklicky,4 M. Giral,1 J. Harb,1 S. Jean-Paul.1

    1INSERM UMR 1064, ITUN, CHU de Nantes, Nantes University, Nantes, France; 2Société d'Accélération du Transfert de Technologies Ouest Valorisation, Rennes, France; 3EA 4275 SPHERE, Biostatistics, Clinical Research and Pharmaco-Epidemiology, Nantes, France; 4Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 5Central European Institute of Technology, Brno University of Technology, Brno, Czech Republic; 6IECM, EA4644 University/ONIRIS USC1383 INRA, ONIRIS, Nantes, France; 7EFS Pays de la Loire, Nantes, France.

    Anti-thymocyte globulins (ATG) are rabbit IgGs against human T cells widely used as induction treatment of kidney recipients. ATG can induce immune-complex diseases including Serum…
  • 2015 American Transplant Congress

    Pretransplant Hepatitis B Viral Infection Increased Risk of Death After Kidney Transplantation

    J. Lee,1 J.-H. Cho,2 J. An,3 C.-D. Kim,2 C. Ahn,4 I. Jung,3 D. Han, C. Lim,3 Y. Kim,4 Y. Kim, J. Lee.3

    1Internal Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Republic of Korea; 2Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea; 3Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 4Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; 5Surgery, Ulsan University Seoul Asan Medical Center, Seoul, Republic of Korea.

    Clinical outcomes have not been well evaluated in kidney transplant recipients (KTRs) with hepatitis B virus (HBV). Here, we aimed to investigate the recent posttransplant…
  • 2015 American Transplant Congress

    Risk of End-Stage Renal Disease After Living Donor Liver Transplantation: Overall Incidence and Comparisons to Deceased Donor Recipients

    D. Goldberg,1 R. Ruebner,2 P. Abt.3

    1Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 2Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Surgery, University of Pennsylvania, Philadelphia, PA.

    Introduction: Since initiation of MELD-based allocation for liver transplants, the risk of end-stage renal disease (ESRD) post-liver transplantation has increased. Recent US data demonstrated comparable,…
  • 2015 American Transplant Congress

    Safer and More Effective Treatment of Acute Postoperative Pain in Living Liver Donors

    D. Ladner,1 R. Fisher,2 J. Guarrera,3 E. Pomfret,4 M. Simpson,4 A. Daud,5 T. Curtis,5 E. Reyes,5 A. Skaro,1 D. Woods.5

    1Northwestern University, Chicago, IL; 2Virginia Commonwealth University, Richmond, VA; 3Columbia University, New York, NY; 4Lahey Clinic, Boston, MA; 5CHS, Northwestern University, Chicago, IL.

    BACKGROUND: As part of Adult-to-Adult Living Donor Liver Transplant Cohort Study (A2ALL), donors were found to experience significant pain post donation, and more than half…
  • 2015 American Transplant Congress

    Immunologic Long-Term Outcome of Living Kidney Transplantation Depending On the Donor-Recipient Relationship

    D. Khadzhynov, F. Halleck, D. Schmidt, S. Kreimer, K. Budde, O. Staeck.

    Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany.

    Background. Only few data is available about long-term immunologic outcomes of living kidney transplantation (KTx) depending on the donor-recepient relationship.Patients and methods. This single center…
  • 2015 American Transplant Congress

    Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens

    K. Omoto,1 D. Toki,1 M. Okumi,1 T. Shimizu,1 H. Ishida,1 K. Honda,2 J. Koike,3 K. Tanabe.1

    1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan; 3Department of Pathology, St. Marianna University, School of Medicine, Kawasaki, Japan.

    OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…
  • 2015 American Transplant Congress

    Respiratory Infections Following Lung Transplantation Leads to De Novo Development of Antibodies to Both Donor HLA and Lung Associated Self-Antigens and Increases the Risk for Bronchiolitis Obliterans Syndrome

    K. George,1 M. Gunasekaran,1 M. Sharma,1 F. Zhou,1 A. Limaye,3 R. Hachem,2 T. Mohanakumar.1

    1Surgery, Washington Univ, St. Louis, MO; 2Medicine, Washington Univ, St. Louis, MO; 3Medicine, Univ Washington, Seattle, WA.

    Background: It is accepted that lower respiratory tract infections (LRI) post lung transplantation (LTx) are a risk factor for the development of Bronchiolitis Obliterans Syndrome…
  • 2015 American Transplant Congress

    Pretransplant Panniculectomy in Patients Previously Denied Access to Renal Transplantation: Addressing Disparities for Candidates With a High-Risk Abdominal Panniculus After Weight Loss

    C. Troppmann,1 C. Bailey,2 J. Kuo,2 C. Santhanakrishnan,1 R. Perez,1 M. Wong.2

    1Transplant Surgery, UC Davis, Sacramento, CA; 2Plastic Surgery, UC Davis, Sacto..

    Some patients (pts) develop a large lower abdominal panniculus following significant weight loss (worsened by age and abdominal wall laxity). CKD pts affected by this…
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