Am J Transplant, Volume 22, Suppl 3 Archives - Page 14 of 190 - ATC Abstracts

2022 American Transplant Congress
Gene Expression Changes Including Long Non-Coding RNAs in Human Hepatic Ischemia Reperfusion Injury
C. Kuscu¹, S. Naik¹, C. Eymard², H. Ingram¹, A. Bajwa¹, D. Maluf³, V. Mas⁴, J. Eason⁵, C. Kuscu¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ³Surgery, University of Maryland, Baltimore, MD, ⁴University of Maryland, Baltimore, MD, ⁵University of Tennessee/Methodist Transplant Institute, Memphis, TN
*Purpose: Ischemia reperfusion injury (IRI) is still one of the major problems in liver transplantation affecting long term outcomes. This study is sought out to…
2022 American Transplant Congress
National Attitudes Towards Early Liver Transplantation for Alcoholic Liver Disease
J. Mitchell¹, K. Nijhar¹, K. Herrick-Reynolds², H. Sung¹, P. Chen¹, D. L. Segev¹, E. King¹, A. Cameron¹
¹Department Of Surgery, Johns Hopkins University, Baltimore, MD, ²Department Of Surgery, Walter Reed National Military Medical Center, Bethesda, MD
*Purpose: Pre-transplant abstinence requirements, notably the 6-month sobriety guideline, limit access to liver transplant for patients with severe alcoholic hepatitis (SAH). This study examines the…
2022 American Transplant Congress
Angiotensin II Type 1 Receptor Antibody in Pediatric Abdominal Organ Transplant: Survey of Clinical Practice in the United States
R. Patnaik, K. Hitchman, N. Mittal, D. Ranch, D. Fritze
University Health Transplant Institute, San Antonio, TX
*Purpose: Some studies correlate Angiotensin II Type 1 Receptor (AT1R) antibodies (Ab) with the development of rejection, vascular complications, and allograft dysfunction in pediatric solid…
2022 American Transplant Congress
Inferior Kidney Transplant Outcomes in Young Adults Transplanted as Children
K. Deville, F. Rosenblum, D. R. Kelly, M. Seifert
UAB School of Medicine, Birmingham, AL
*Purpose: Adolescence (age 13-17 years) has been identified as a high-risk age interval for pediatric kidney transplant recipients, with accelerated rates of late acute rejection…
2022 American Transplant Congress
Circulating Galectin-3 Levels Increase in Syngeneic Rat Recipients of Vascularized Composite Allografts Subjected to Prolonged Ischemia
Z. Wang¹, B. Li¹, Y. Wang¹, D. Yoeli¹, N. Nakra¹, N. Limon De La Rosa¹, A. A. Su¹, A. Jani¹, D. W. Mathes¹, K. M. Washington¹, E. Farkash², C. A. Huang¹
¹University of Colorado, Denver | Anschutz Medical Campus, Aurora, CO, ²University of Michigan, Ann Arbor, Ann Arbor, MI
*Purpose: During the process of transplantation, organs and tissue are necessarily subjected to some degree of hypoxic and ischemic injury during procurement, preservation and following…
2022 American Transplant Congress
Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation
E. Hafiz¹, W. H. El-Maadawy², M. Hassan³, M. H. Badawy⁴, S. Eldahshan⁴, A. AbuSeada⁵
¹Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, ²Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, ³Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁴Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, ⁵Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt
*Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
2022 American Transplant Congress
Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not
C. OBrien¹, P. Hernandez², S. Concors², Z. Wang¹, G. Ge¹, W. Hancock³, M. Levine²
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…
2022 American Transplant Congress
Low-Dose Aspirin is More Critical Than Statins in Preventing Transplant Renal Artery Stenosis
B. Ji, X. Tian, G. Jing, T. Yan, X. Wu, G. Cao, C. Zhang
Urology, Henan Provincial People's Hospital, Zhengzhou, China
*Purpose: To explore the clinical value of low-dose aspirin (100mg) and statins (10 ~ 20mg) in the prevention of transplant renal artery stenosis (TRAS).*Methods: A…
2022 American Transplant Congress
Site-Directed Mutagenesis as a Tool to Investigate Immunogenicity of HLA Epitopes for Humoral Alloreactivity
C. H. Maguire¹, P. Crivello², A. Tambur¹
¹Northwestern University, Chicago, IL, ²University Hospital Essen, Essen, Germany
*Purpose: Molecular mismatch load (MML) analysis has been a proposed approach to assess donor/recipient compatibility in support of organ allocation algorithms. While conceptually appealing, MML…
2022 American Transplant Congress
Hold the Opioids Please: Long-Term Outcomes Following an Opioid Minimization Protocol in Kidney Transplantation
T. Carcella, N. Patel, J. Marable, J. Fleming, P. Baliga, D. Dubay, S. Bethi, D. Taber, V. Rohan
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use following kidney transplantation (KTX) is associated with an increased risk of graft loss and mortality. Opioid minimization strategies and protocols have demonstrated…