2022 American Transplant Congress
LGALS1 is Expressed in Glomerular Endothelial Cells and Induced Upon Stimulation with Anti-HLA Antibody
*Purpose: Antibody-mediated rejection (AMR) accounts for >50% of premature kidney graft loss. AMR is caused by donor specific antibodies (DSA) against human leukocyte antigens (HLA)…2022 American Transplant Congress
Kidney Transplantation from Covid-19 Deceased Donors
Medicine/Nephrology, Washington University in St. Louis, St. Louis, MO
*Purpose: Transplant volumes decreased significantly during the first months of global pandemic of COVID-19, followed by a shift in the standard of care of transplant…2022 American Transplant Congress
Frequency of Cervical Cancer Screening in Solid Organ Transplant Recipients
*Purpose: Human papillomavirus-related anogenital malignancies disproportionately affect solid organ transplant recipients (SOTR) compared to the general population. Proposed cervical Pap testing intervals for SOTR differ…2022 American Transplant Congress
Use of Belatacept in Non-Compliant Adolescent Patients
1Nemours Children's Health, Wilmington, DE, 2Nationwide Children's Hospital, Columbus, OH
*Purpose: Adolescents are at high risk for kidney transplant rejection due to non-compliance. While intravenous (IV) maintenance medications are FDA approved for adults, there is…2022 American Transplant Congress
Presence of AT1R Antibody Pre-Transplant Does Not Correlate with Rejection in a Large Pediatric Kidney Transplant Cohort
*Purpose: Describe correlations between pre-transplant (PreTXP) presence of anti-angiotensin II receptor type 1 antibodies (AT1RAb) and post-transplant (PostTXP) outcomes in a pediatric kidney transplant (PKT)…2022 American Transplant Congress
The Role of HNF4α in Renal Ischemia Reperfusion Injury
Toronto General Hospital Research Institute, Toronto, ON, Canada
*Purpose: Ischemia reperfusion injury (IRI) affects all solid organ transplants and impairs renal graft function. However, the mechanisms by which IRI affects grafts are incompletely…2022 American Transplant Congress
Early Post-Operative Thrombotic Microangiopathy in Deceased Donor Kidney Transplant: A Retrospective Case Series
*Purpose: Transplant associated thrombotic microangiopathy (TA-TMA) is characterized by endothelial injury along with thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and kidney graft dysfunction. It can be…2022 American Transplant Congress
Impact of Total Parenteral Nutrition on Donor Kidneys During Oxygenated Preservation at 22ºC Ex Vivo
1London Health Sciences Centre, London, ON, Canada, 2Western University, London, ON, Canada
*Purpose: Recent studies have shown that ex vivo preservation at 37 º C can reduce kidney injury compared to current clinical practice. However, to mitigate…2022 American Transplant Congress
Outcomes After Kidney Transplantation in Post Bariatric Surgery Patients: Systematic Review
1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic, Rochester, MN
*Purpose: Morbid obesity is a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes. Bariatric surgery (BS) is increasingly performed in…2022 American Transplant Congress
Waitlist Meldna Variation One-year Prior To Liver Transplant Predicts Length Of Stay At The Time Of Transplant
1University of Minnesota, Minneapolis, MN, 2Cleveland Clinic Foundation, Cleveland, OH
*Purpose: MELDNa is used to estimate 90-day mortality in the waitlist. MELDNa variation between cross-sections has shown a better predictivity than when analyzed as a…
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