Am J Transplant, Volume 22, Suppl 3 Archives - Page 190 of 190 - ATC Abstracts

2022 American Transplant Congress
Factor V Leiden Heterozygosity and Live Donor Liver Donation – A Single Center Analysis
D. Reddy, S. Ganesh, A. M. Thompson, V. Gunabushanam, A. Ganoza, M. Molinari, A. Tevar, C. Hughes, A. Humar
Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Living donor liver transplantation (LDLT) accounts for only a small percentage (< 6%) of all liver transplants performed for adult recipients in the western…
2022 American Transplant Congress
Organ Transplant Outcomes from Donors with Positive SARS-CoV-2 PCRs in New York: A Case Series
A. L. Friedman¹, M. Pereira², M. Rana³, J. Akpede⁴, A. Dhand⁵
¹LiveOnNY, New York, NY, ²New York Presbyterian Hospital, New York, NY, ³Icahn School of Medicine at Mount Sinai, New York, NY, ⁴LiveOnNY, Long Island City, NY, ⁵Westchester Medical Center, Chappaqua, NY
*Purpose: Rapid evolution of the SARS-CoV-2 pandemic over the past 24 months has demanded agility in managing selection criteria for deceased organ donors, with the…
2022 American Transplant Congress
Survey of Current Transplant Center Practices Regarding Covid-19 Vaccine Mandates in the United States
B. E. Hippen¹, D. Axelrod², K. Maher³, R. Xi³, D. Kumar⁴, M. Schnitzler³, K. Lentine³
¹Head of Transplant Medicine, Fresenius Medical Care, Charlotte, NC, ²University of Iowa Transplant Clinic, Iowa City, IA, ³St. Louis University School of Medicine, St. Louis, MO, ⁴Ajmera Transplant Centre, Toronto, ON, Canada
*Purpose: We surveyed current policies of transplant centers regarding a COVID-19 vaccine mandate, and rationales for or against a mandate policy.*Methods: An electronic survey was…
2022 American Transplant Congress
Disulfide HMGB1 Reprograms Macrophages to Induce Alloimmunity via TLR4 and TLR9 Pathways Following Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, F. Kaldas², R. Busuttil³, D. Gjertson¹, J. Kupiec-Weglinski¹, E. Reed¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, ²University of California Los Angeles (Multi-organ), Los Angeles, CA, ³Surgery, University of California, Los Angeles, Los Angeles, CA
*Purpose: Human hepatocellular damage caused by ischemia reperfusion injury (IRI) generates the disulfide form of HMGB1 (diS HMGB1), eliciting myeloid cell activation and proinflammatory cytokine…
2022 American Transplant Congress
Binding Mechanisms For Donor Dc-derived Exosomes To Cross-dress Of Recipient Dc
L. ZHANG¹, X. LI¹, J. LIU¹, H. WEI¹, C. LI¹, A. HUANG², C. ZHENG¹, Q. LIU¹
¹Department of Biochemistry, Southern University of Science and Technology, Shenzhen, China, ²Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Our previous evidence suggests donor dendritic cell (DC)-derived exosomes cross-dress recipient DC after heart transplantation in mice. This process plays a critical role in…
2022 American Transplant Congress
Dynamic Risk Prediction of Kidney Graft Failure After Deceased Donor Transplant
D. G. Hu¹, H. Thiessen Philbrook¹, S. Mohan², I. Hall³, M. Doshi⁴, K. F. Kerr⁵, C. R. Parikh¹
¹Johns Hopkins University, Baltimore, MD, ²Columbia University Medical Center, New York, NY, ³University of Utah, Salt Lake City, UT, ⁴University of Michigan, Ann Arbor, MI, ⁵University of Washington, Seattle, WA
*Purpose: Identifying kidney transplant recipients at risk of graft failure allows for early intervention in clinical care. We developed a dynamic risk prediction model based…
2022 American Transplant Congress
18 Month Review of Liver Acuity Circles Allocation
J. Foutz¹, S. Noreen¹, M. Cafarella¹, A. Wilk¹, J. Trotter², S. Biggins³, J. Pomposelli⁴
¹United Network for Organ Sharing, Richmond, VA, ²Baylor University Medical Center, Dallas, TX, ³University of Washington, Seattle, WA, ⁴University of Colorado, Aurora, CO
*Purpose: Acuity circles (AC) allocation was implemented on 2/4/2020 with a goal of removing DSA and region from liver allocation and broadening the distribution of…
2022 American Transplant Congress
Increased Waitlist Mortality in Pediatric Liver Transplant Candidates with Greater Distance from Transplant Center
C. X. Qin, T. Ishaque, S. M. Frey, A. B. Massie, A. M. Cameron, D. L. Segev, E. A. King
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Greater distance from transplant center in adult liver transplant (LT) candidates is associated with increased waitlist mortality. Pediatric LT candidates have higher waitlist mortality…
2022 American Transplant Congress
25 Years of a Standardized Living Donor (LD) Intestinal Transplant Technique – What Has Been Achieved?
R. Gruessner¹, A. C. Gruessner²
¹SUNY Downstate Medical Center, Brooklyn, NY, ²SUNY Downstate Medical Center, Brooklyn, MA
*Purpose: The indication for intestinal transplantation (ITX) is irreversible intestinal failure with dependence on total parenteral nutrition (TPN). Most intestinal transplants are from deceased donors…
2022 American Transplant Congress
Perfusate Metabolites and Association with Pump Perfusion and Allograft Failure
R. X. Liu¹, N. Koyawala², H. T. Philbrook², I. Hall³, P. Reese⁴, S. Mohan⁵, M. Doshi⁶, C. Parikh¹
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, ³University of Utah School of Medicine, Salt Lake City, UT, ⁴University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ⁵University of Columbia Vagelos College of Physicians & Surgeons, New York, NY, ⁶University of Michigan, Ann Arbor, MI
*Purpose: While hypothermic machine perfusion (HMP) is associated with improved kidney graft viability, the exact biological mechanisms underlying this association are unknown. The goal of…