Am J Transplant, Volume 22, Suppl 3 Archives - Page 103 of 190 - ATC Abstracts

2022 American Transplant Congress
Brain Death as a Novel Preclinical Human Model for the Advancement of Medicine
C. Killian¹, B. Orandi¹, D. Anderson¹, V. Kumar², K. Stegner¹, N. Budd¹, S. Macedon¹, A. Shunk³, P. Porrett¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham Hospital, Birmingham, AL, ³Legacy of Hope, Birmingham, AL
*Purpose: For interventions that lack US Food and Drug Administration approval, testing is limited and relies on preclinical animal models to determine safety and efficacy.…
2022 American Transplant Congress
The Role of Gastrointestinal Pathogen PCR Testing in Liver Transplant Recipients Hospitalized with Diarrheal Illness
C. K. Ching¹, Y. R. Nobel², M. R. Pereira³, E. C. Verna⁴
¹Department of Medicine, Columbia University Medical Center, New York, NY, ²Division of Digestive and Liver Diseases, Columbia University Medical Center, New York, NY, ³Division of Infectious Diseases, Columbia University Medical Center, New York, NY, ⁴Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY
*Purpose: Diarrhea is a common complication among liver transplant (LT) recipients and can result in significant morbidity. The development of PCR-based multiplex gastrointestinal (GI) pathogen…
2022 American Transplant Congress
Kidney, Lung and Liver Transplant Patients’, Kidney Transplant Candidates’ and Living Donors’ Perspectives on the Role of Patients’ Stories and Creative Writing in Transplantation: An Exploratory Study
L. Laneuville¹, F. Ballesteros Gallego², A. Affdal², B. Gagnon-Chainey³, L. Brassard², P. Millot³, S. Harel³, C. Mavrikakis³, M. Malo³, M. Fortin²
¹McGill University, Montreal, QC, Canada, ²CRCHUM, Montreal, QC, Canada, ³University of Montreal, Montreal, QC, Canada
*Purpose: Organ transplantation is associated with medical, psychological and existential challenges for patients. Patients’ experiential knowledge can help other patients facing these challenges. Patients’ stories…
2022 American Transplant Congress
Use of Viral Specific T Cell Therapy in Solid Organ Transplant Recipients – A Single Center Experience
G. McGraw¹, N. Patel², K. Patel¹, S. Bumb³, A. Govil⁴, M. Anand¹
¹University of Cincinnati, Cincinnati, OH, ²Nephrology, University of Cincinnati, Cincinnati, OH, ³Nephrology, Internal Medicine, University of Cincinnati Medical Center, Blue Ash, OH, ⁴Univ of Cincinnati, Cincinnati, OH
*Purpose: Viral infections such as BK virus (BKV), cytomegalovirus (CMV) and adenovirus after kidney transplantation negatively impact outcomes in solid organ transplant (SOT) recipients despite…
2022 American Transplant Congress
A Novel, High Throughput Droplet Digital PCR-Based Indel Quantification Method for the Detection of Circulating Donor-Derived Cell-Free DNA After Kidney Transplantation
J. G. Verhoeven¹, K. Boer¹, A. M. Peeters¹, M. C. Clahsen-van Groningen², J. I. Roodnat¹, J. van de Wetering¹, D. Nieboer³, D. A. Bost⁴, C. C. Baan¹, D. A. Hesselink¹
¹Department of Internal Medicine, Erasmus MC Transplant Institute, Rotterdam, Netherlands, ²Department of Pathology, University Medical Center Rotterdam, Rotterdam, Netherlands, ³Department of Public Health, University Medical Center Rotterdam, Rotterdam, Netherlands, ⁴JETA Molecular, Utrecht, Netherlands
*Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising minimally invasive biomarker for acute rejection (AR) in kidney transplant recipients. To assess the diagnostic value of…
2022 American Transplant Congress
Peripheral Blood Immune Cell Profiles of Corneal Transplant with and without Acute Rejection
J. Hjortdal¹, M. Griffin², C. C. Murphy³, S. Brouard⁴, N. Degauque⁴
¹Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark, ²National University of Ireland, Galway, Galway, Ireland, ³Royal Victoria Eye and Ear Hospital, Dublin, Ireland, ⁴Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France
*Purpose: Acute rejection (AR) of allogeneic corneal transplantation (CT) has a profound effect on subsequent graft survival, indicating that immunological damage is often not fully…
2022 American Transplant Congress
Impact of Sars-CoV-2 Vaccination on Donor-Derived Cell Free DNA Levels in Renal Transplant Recipients
H. Alvarado Verduzco, E. Daniel, D. Kim, A. Hussain, S. Mohan, D. Cohen
Columbia University Irving Medical Center, New York, NY
*Purpose: COVID-19 poses a disproportionate threat to renal transplant recipients (RTR), who are chronically immunosuppressed. Studies have indicated a 16% mortality rate compared to
2022 American Transplant Congress
Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial
M. M. Pascale¹, G. Bianco¹, L. Ferri¹, F. Giovinazzo¹, A. Liguori², G. Marrone², A. Grieco², S. Agnes¹
¹General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, ²Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy
*Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…
2022 American Transplant Congress
Steatosis Following Liver Transplantation for Nonalcoholic Steatohepatitis is Associated with a Higher Rate of Cardiovascular Complications
W. Alhamoudi¹, S. Alqahtani², K. Bzeizi², A. Albenmousa², Y. Saleh², D. Broering², S. Alghamdi²
¹Medicine, King Saud University, Riyadh, Saudi Arabia, ²Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
*Purpose: Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to become the leading indication for liver transplantation (LT) worldwide. Objectives: to evaluate the prevalence of…
2022 American Transplant Congress
Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends
D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis
The Mount Sinai Hospital, New York, NY
*Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…