ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Enteric Conversion After Bladder-drained Kidney-pancreas Transplantation

    S. Sivan, M. Ortigosa-Goggins, M. Patel, M. Morsi, L. Chen, J. Figueiro, G. Ciancio, G. Burke

    Miami Transplant Institute, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL

    *Purpose: In simultaneous kidney-pancreas transplantation (SPK), bladder (BD) and enteric (ED) are both options for pancreaticoduodenal exocrine drainage. While BD provides good early and long…
  • 2021 American Transplant Congress

    Impact of Electronic Donor Referral Technology on Deceased Donor Referrals

    B. Boyarsky1, J. R. DiRito2, K. Vanterpool1, J. Piano3, W. Liu3, J. Hewlett4, C. Trahan4, D. Segev1, M. Levan1, A. Massie1, P. Niles4

    1Johns Hopkins, Baltimore, MD, 2Yale, New Haven, CT, 3Transplant Connect, Santa Monica, CA, 4Southwest Transplant Alliance, Dallas, TX

    *Purpose: Hospitals likely fail to refer many medically eligible potential deceased donors to OPOs. As such, increasing eligible referrals may increase the donor pool. We…
  • 2021 American Transplant Congress

    Summary of the OPTN’s Policy and System Modifications in Response to the COVID-19 Pandemic

    A. Wilk, S. Taranto, C. Jett, L. Cartwright

    UNOS, Richmond, VA

    *Purpose: In April 2020, the OPTN made several policy and system modifications in response to the growing COVID-19 pandemic including updates to candidate lab data,…
  • 2021 American Transplant Congress

    Monoclonal Antibodies for Covid-19 in Patients with Solid Organ Transplant Recipients

    L. Hasan1, H. Hardgrave2, T. Osborn3, R. Dare1, L. Burdine4, E. Giorgakis4, J. Rico1

    1Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 2University of Arkansas for Medical Sciences, Little Rock, AR, 3Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, 4Transplant surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: The FDA has issued Emergency Use Authorization (EUA) for monoclonal antibodies for the treatment of mild to moderate COVID-19 in patients at risk for…
  • 2021 American Transplant Congress

    Myeloid Foxo1-β-catenin Axis Regulates Hedgehog/Gli1 Signaling and Controls NLRP3-Mediated Innate Immune Responses in Sterile Inflammatory Liver Injury

    D. Xu, C. Li, M. Sheng, Y. Lin, Y. Tian, Y. Zhan, A. J. Coito, R. W. Busuttil, D. G. Farmer, J. W. Kupiec-Weglinski, B. Ke

    Surgery, Dumont - UCLA Transplant Center, Los Angeles, CA

    *Purpose: Foxo1 plays important roles in cell metabolism, oxidative stress, inflammation, and apoptosis. Activation of Hedgehog/Gli1 signaling regulates cell growth, differentiation, and immune function. However,…
  • 2021 American Transplant Congress

    Systematic Screening of Kidney Transplant Patients Points Towards Deficits in Neutralizing Antibody Capacity Against Sars-cov-2

    V. Wijtvliet1, K. K. Ariën2, J. Mariën2, B. Peeters3, R. Hellemans4, A. Massart4, S. Van Hees1, P. Moons5, H. Theeten6, P. Van Damme6, H. Goossens7, B. Y. De Winter1, K. J. Ledeganck1, D. Abramowicz4

    1Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium, 2Department of Biomedical Sciences, Institute of Tropical Medicine and University of Antwerp, Antwerp, Belgium, 3Department of Laboratory Medicine, Antwerp University Hospital, Antwerp, Belgium, 4Department of Nephrology and Hypertension, Antwerp University Hospital, Antwerp, Belgium, 5Biobank, Antwerp University Hospital, Antwerp, Belgium, 6Centre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium, 7Department of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium

    *Purpose: The majority of kidney transplant recipients (KTR) is able to develop SARS-CoV-2 antibodies (Abs). Little is known about the virus neutralizing capacity of these…
  • 2021 American Transplant Congress

    Impact of Advanced Renal Dysfunction on Post-Transplant Outcomes After Living Donor Liver Transplantation in the United States

    T. Bittermann1, N. Kaur2, P. L. Abt1, K. M. Olthoff1, J. K. Heimbach3, J. Emamaullee2

    1University of Pennsylvania, Philadelphia, PA, 2University of Southern California, Los Angeles, CA, 3Mayo Clinic College of Medicine, Rochester, MN

    *Purpose: Survival after living donor liver transplantation (LDLT) in the U.S. is excellent. However, the significance of pre-transplant kidney disease on outcomes after LDLT is…
  • 2021 American Transplant Congress

    Evaluation and Experience with Hepatitis C Positive to Negative PancreasTransplantation

    B. K. Lindner, B. Thomas, M. Cooper, S. Yi, P. Abrams

    Medstar Georgetown University Hospital, Washington, DC

    *Purpose: The use of hepatitis C virus (HCV) positive organs for transplant to HCV negative recipients has been reported on and has gained popularity across…
  • 2021 American Transplant Congress

    Insulin Secretion and Insulin Resistance Trajectories Over 1 Year After Kidney Transplantation: A Multicenter Prospective Cohort Study

    B. Jun Bae, C. Oh

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: We investigated the changing patterns of insulin secretion and resistance and risk factors contributing to the development of post-transplant diabetes mellitus (PTDM) in kidney…
  • 2021 American Transplant Congress

    Role of Baseline PD-1 Checkpoint Inhibitor Pathway Expression in Bridge to Liver Transplant Hepatocellular Carcinoma

    K. Nunez, T. Sandow, M. Hibino, A. Cohen, P. Thevenot

    Ochsner Health, New Orleans, LA

    *Purpose: Response to first line liver-directed therapy (LDT) in hepatocellular carcinoma (HCC) has important implications in both bridge to transplant (BTT) success as well as…
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