Am J Transplant, Volume 21, Suppl 3 Archives - Page 96 of 139 - ATC Abstracts

2021 American Transplant Congress
Rural Dialysis Facilities are Associated with Better Dialysis Quality but Less Home Dialysis Use
J. T. Adler¹, L. Xiang¹, S. S. Waikar²
¹Surgery, Brigham and Women's Hospital, Boston, MA, ²Medicine, Boston Medical Center, Boston, MA
*Purpose: Dialysis facility quality is associated with patient outcomes. The 60 million rural dwellers across the United States are older, more likely to live in…
2021 American Transplant Congress
Precision Medicine in Renal Transplantation: Structural Biology of HLA Defines Allelic Binding of Cardinal Pathogenic Viruses in Transplantation
K. R. Sherwood¹, A. Nguyen², J. Tran¹, O. Gunther³, A. Nellore², R. Thompson², J. Lan¹, L. Allan¹, P. A. Keown¹
¹Vancouver General Hospital, Vancouver, BC, Canada, ²Biomedical Engineering, Oregon Health & Science University, Portland, OR, ³Gunther Analytics, Vancouver, BC, Canada
*Purpose: The incidence, clearance and clinical expression of viremia post-Tx are heterogeneous, complicating prediction, prognosis and therapy. We postulated that variation viral presentation related to…
2021 American Transplant Congress
Impact of Machine Perfusion of the Heart on Abdominal Organ Procurement from Donation After Cardiac Death Donors
C. Feizpour, C. Hwang, A. Shubin, J. Shah, L. DeGregoria, S. Hanish, P. Vagefi, M. MacConmara
Department of Surgery, Division of Surgical Transplantation, University of Texas Southwestern Medical Center, Dallas, TX
*Purpose: Superior preservation with normothermic machine perfusion devices has been demonstrated in thoracic and abdominal allografts, especially DCD donation, where clinical utilization of DCD hearts…
2021 American Transplant Congress
Single Cell Rna-Sequencing of Urinary Cells and Defining the Immune Landscape of Rejection in Human Kidney Allografts
T. Muthukumar¹, H. Yang¹, A. Belkadi², G. Thareja², C. Li¹, C. Snopkowski¹, K. Chen¹, T. Salinas¹, M. Lubetzky¹, J. Lee¹, D. Dadhania¹, K. Suhre², M. Suthanthiran¹
¹Nephrology, NY Presbyterian- Weill Cornell Medical College, New York, NY, ²Physiology and Biophysics, Weill Cornell Medicine-Qatar, Doha, Qatar
*Purpose: Transcriptome-based clustering of urinary cells in kidney transplant recipients may help identify cell-type specific injury and develop cell-type specific biomarkers for the noninvasive assessment…
2021 American Transplant Congress
The Trifecta Study: Calibrating Circulating Donor-Derived Cell-Free DNA at the Time of Indication Biopsies Against the Molecular Phenotype of the Biopsy Reveals a Prominent Association with NK Cell Genes
P. Halloran¹, Z. Demko², A. Prewett², J. Reeve¹, P. Billings²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²Natera Inc., San Carlos, CA
*Purpose: The international, multicenter, prospective Trifecta study was designed to calibrate dd-cfDNA% measurements in blood at the time of indication biopsy against the molecular characteristics…
2021 American Transplant Congress
Is There a Role for Donor-Specific Antibody Testing in Simultaneous Liver-Kidney Transplantation? A Single Center Analysis of Outcomes
A. Das, A. Barbetta, D. Remulla, C. Goldbeck, T. Maw, J. Kim
University of Southern California, Los Angeles, CA
*Purpose: Simultaneous liver-kidney transplantation (SLKT) has grown exponentially since its conception in the 1960’s. The role for donor specific antibody (DSA) testing in SLKT is…
2021 American Transplant Congress
Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury in a Renal Specific Manner
C. S. O'Brien, P. Hernandez, Z. Wang, G. Ge, W. Hancock, M. H. Levine
Surgery, University of Pennsylvania, Philadelphia, PA
*Purpose: Renal Ischemia Reperfusion Injury (IRI) is a major contributor to delayed graft function (DGF) in kidney transplantation. Previously, we have shown lower rates of…
2021 American Transplant Congress
Associations of Lack of Insurance and Other Sociodemographic Traits with Deficiencies in Follow-Up After Living Kidney Donation
K. Lentine¹, R. Hays², N. Lam³, A. Tietjen⁴, A. Muiru⁵, H. Xiao¹, A. Garg⁶, C. Thomas⁷, G. McNatt⁷, R. Howey⁸, U. Lebron-Banks⁹, M. Cooper¹⁰, M. Conboy¹¹, B. Kasiske¹¹
¹Saint Louis Univ, Saint Louis, MO, ²Univ of Wisconsin, Madison, WI, ³Univ of Calgary, Calgary, AB, Canada, ⁴St. Barnabas, Livingston, NJ, ⁵Univ of California, San Francisco, San Francisco, CA, ⁶Western Univ, London, ON, Canada, ⁷Univ of Iowa, Iowa City, IA, ⁸Toyon Associates, Concord, CA, ⁹New York Presb Hosp, New York, NY, ¹⁰Medstar-Georgetown, Washington, DC, ¹¹SRTR, Minneapolis, MN
*Purpose: Follow-up after living kidney donation in the United States has improved with recent policy mandates. We hypothesized that lack of insurance at donation may…
2021 American Transplant Congress
Psychosocial Determinants of Regimen Adherence Among Kidney Transplant Recipients
A. Balakrishnan, S. Bailey, D. Mroczek, M. Serper, D. P. Ladner, M. S. Wolf
Northwestern University, Chicago, IL
*Purpose: There is increasing evidence suggesting a high prevalence of inadequate medication adherence among kidney transplant recipients (KTRs) and its subsequent consequences on health outcomes.…
2021 American Transplant Congress
The Australian and New Zealand Living Kidney Donor Profile Index
G. L. Irish¹, S. Chadban¹, N. Boudville², S. B. Campbell³, J. Kanellis⁴, P. A. Clayton¹
¹Australian and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, ²Medical School, University of Western Australia, Perth, Australia, ³Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia, ⁴Department of Nephrology, Monash Health, Melbourne, Australia
*Purpose: Risk scores may aid risk quantification and decision-making in kidney transplantation. The Living Kidney Donor Profile Index (LKDPI) was developed to choose between living…