Am J Transplant, Volume 21, Suppl 3 Archives - Page 98 of 139 - ATC Abstracts

2021 American Transplant Congress
Early Outcome of Heart-Kidney Transplantation in the Current Heart Allocation System in the United States
S. Rao¹, A. Doyle¹, D. Brennan², S. Constantinescu³
¹University of Virginia, Charlottesville, VA, ²Johns Hopkins Medical Institute, Baltimore, MD, ³Lewis Katz School of Medicine at Temple University, Philadelphia, PA
*Purpose: In the United States, heart allograft allocation is a primary determinant for heart-kidney transplantation (HKT). We analyzed the OPTN dataset and compared the outcomes…
2021 American Transplant Congress
Systematic Implementation of Alcohol Screening Program Using Urine Ethyl Glucuronide Can Identify Post-transplant Alcohol Use and Aid Return to Sobriety in Liver Transplant Recipients
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett¹, R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Rates of liver transplantation (LT) for alcohol-related liver disease (ALD) are increasing, particularly in patients with acute alcoholic hepatitis. Post-LT alcohol (ETOH) use has…
2021 American Transplant Congress
Impact of Lung Allocation Score Cohort Update
M. Skeans¹, A. Wey¹, E. Lease², C. Lehr³, M. Valapour³
¹SRTR, Minneapolis, MN, ²Univ of Washington, Seattle, WA, ³Cleveland Clinic, Cleveland, OH
*Purpose: The lung allocation score (LAS) was last revised in February, 2015, based on waitlist (WL) and posttransplant (PT) survival model cohorts from 2006-2008 and…
2021 American Transplant Congress
Utility of Non-Invasive Rejection Biomarkers to Guide Immunomodulation in Kidney Transplant Patients with Active Covid-19 Infection
J. Christensen, G. Gupta, A. Bryson, S. Paluri, R. Thompson, S. Sterling, N. Vissichelli, P. Kimball, D. Kumar
VCUHealth, Richmond, VA
*Purpose: Treatment of Coronavirus Disease 2019 (COVID-19) infection in organ transplant recipients has involved reduction of immunosuppression (IS). It is plausible that the cytokine release…
2021 American Transplant Congress
Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach
H. Iwamoto¹, M. Sugimoto², O. Konno¹, I. Akashi³, M. Okihara¹, Y. Kihara¹, T. Ueno¹
¹Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, ²Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, ³Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
2021 American Transplant Congress
Mortality in Organ Transplant Recipients with Covid-19 Compared to Non-transplant or Waitlisted Patients: A Meta-analysis
A. H. Lerner, E. Klein, D. Farmakiotis
Rhode Island Hospital/Brown University, Providence, RI
*Purpose: Organ transplant recipients (OTR) are considered at high risk for adverse outcomes from COVID-19. However, mortality rates range from 30%. Some studies found that…
2021 American Transplant Congress
TIGIT Identifies Polyfunctional Donor-Specific CD4+ T Cells Lost After Kidney Transplantation
A. C. van der List, N. H. Litjens, M. G. Betjes, M. Klepper
Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands
*Purpose: Development of T-cell hyporesponsiveness to donor antigen may explain the substantial decrease in the risk for acute rejection in the years following kidney transplantation.…
2021 American Transplant Congress
Conversion to Belatacept Based Immunosuppression Regimen in Kidney Transplant Patients: Lessons Learned
R. Saidi, N. Huang, C. Yang, I. Movileanu, K. Ecal, A. Senay, O. Pankewycz, R. Dvorai, R. Shahbazov, M. Laftavi
SUNY Upstate, Syracuse, NY
*Purpose: The costimulatory inhibitor, belatacept (Bela) has been shown to be an effective alternative in several clinical situations including calcineurin toxicity, de novo alloantibody formation…
2021 American Transplant Congress
Degree of T Cell Infiltration Predicts Treatment Response in Pediatric Liver Late Acute Cellular Rejection
M. Rogers, G. Begum, Q. Sun, A. Peters
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Late acute cellular rejection (ACR) occurs >6mo post-liver transplant and is associated with chronic rejection and allograft loss. Currently, no diagnostic features predict ACR…
2021 American Transplant Congress
A Comparison of Pediatric Intestine Transplant Between the Current Era (2015-2019) and the Peak Period (2002-2006)
S. Horslen¹, T. Weaver², M. Skeans²
¹Seattle Children's Hospital, Seattle, WA, ²SRTR, Minneapolis, MN
*Purpose: Demand for intestine transplants in children grew from its clinical inception in the late 1980s to a peak in 2007 of 111 small bowel-containing…