Am J Transplant, Volume 21, Suppl 3 Archives - Page 88 of 139 - ATC Abstracts

2021 American Transplant Congress
Implications of Trends in Child to Parent Kidney Donation in Whites and African Americans
N. Jean, S. Krishnamoorthy, Y. Kyeso, P. Cunningham, N. Murthy, R. McGill, M. Josephson
Nephrology, University of Chicago, Chicago, IL
*Purpose: Racial disparities in access to transplantation referral, wait listing and transplant receipt are well described. African Americans (AA) receive fewer living donor transplants than…
2021 American Transplant Congress
Mhealth Family Self-Management Intervention for Families of Transplanted Children
S. M. Lerret¹, R. White-Traut², B. Medoff-Cooper³, S. I. Ahamed⁴, P. Simpson⁵, R. Schiffman⁶
¹Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, ²Children's Wisconsin, Milwaukee, WI, ³University of Pennsylvania, Philadelphia, PA, ⁴Department of Computer Science, Marquette University, Milwaukee, WI, ⁵Department of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, ⁶University of Wisconsin Milwaukee, Milwaukee, WI
*Purpose: Nearly 2,000 children undergo solid organ transplant in the US annually. In our previous research with transplant families, parents reported difficulty coping with the…
2021 American Transplant Congress
Single Cell RNA Sequencing of Tim1- B Cells and Tim1+ Regulatory B Cells
Q. Fu¹, K. Lee², K. Deng², D. Agarwal³, P. v. Galen⁴, C. G. Rickert², G. Huai², H. Yang¹, C. LeGuern², S. Deng¹, J. F. Markmann²
¹Organ Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Sciences and Technology of China, Chengdu, China, ²Center for Transplantation Sciences, MGH, Boston, MA, ³Division of Transplantation, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Division of Hematology, Brigham and Women's Hospital, Boston, MA
*Purpose: Tim1 signaling has an important role in inducing and maintaining the function of Regulatory B cells. Our previous study showed that Tim1+ Bregs prolong…
2021 American Transplant Congress
Transplant Trainee Education and Recruitment Experiences
D. E. Cassidy¹, A. E. Gomez-Rexode¹, J. R. Santos-Parker¹, M. S. Anderson², L. M. McElroy³, M. E. Byrnes², S. A. Waits², V. S. Valbuena²
¹University of Michigan Medical School, Ann Arbor, MI, ²Department of Surgery, University of Michigan Health System, Ann Arbor, MI, ³Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: The demand for training in abdominal transplantation has continued to decrease. General surgery residents have less exposure to transplant surgery, creating a need for…
2021 American Transplant Congress
A New Triage-based Approach to Managing Transplant Referrals
H. L. Walther
Division of Kidney & Pancreas Transplantation, UCI Health, Orange, CA
*Purpose: To develop and implement a novel triage-based approach to the management of referrals for kidney transplant evaluation*Methods: The transplant nurse coordinator dedicated to referral…
2021 American Transplant Congress
Invariant Nkt Cells Promote Expansion of Novel Cxcr3⁺Ccr4⁺Cd8⁺ T Cells in the Liver Following Allogeneic Hepatocyte Transplant
J. Zimmerer¹, B. Ringwald², S. Chaudhari¹, J. Han¹, C. M. Peterson¹, R. T. Warren¹, M. Hart¹, M. Abdel-Rasoul³, G. Bumgardner¹
¹OSU, Columbus, OH, ²Medical Student Research Program, OSU, Columbus, OH, ³Center for Biostatistics, OSU, Columbus, OH
*Purpose: Hepatocyte transplantation represents a treatment for metabolic diseases and a bridge therapy to whole organ transplant but is limited in part by cell immunogenicity.…
2021 American Transplant Congress
Iguratimod Prevents Antibody-mediated Rejection by Regulating Germinal Center Formation and Antibody Production
H. Zhang, A. Chandraker, P. Sage, N. Murakami
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
*Purpose: Antibody-mediated rejection (ABMR) is a major cause of chronic renal allograft failure without effective treatment, and developing a novel therapy is an urgent need.…
2021 American Transplant Congress
Extracellular Vesicles from Patients with Diabetic Nephropathy Induce Endothelial Dysfunction Through Icam-1 and Vcam-1 in an In Vitro Model
E. Montagud-Marrahi¹, S. Torramadé-Moix², M. Ramirez-Bajo³, J. Rovira³, E. Bañón-Maneus³, E. Hermida¹, F. Diekmann¹, M. Palomo⁴, M. Díaz-Ricart², P. Ventura-Aguiar¹
¹Nephrology and Kidney Transplantation Department, Hospital Clínic de Barcelona, Barcelona, Spain, ²Hematopathology Department, Hospital Clínic de Barcelona, Barcelona, Spain, ³Nephrology and Transplant Experimental Laboratory (LENIT), Hospital Clínic de Barcelona, Barcelona, Spain, ⁴Josep Carreras Leukaemia Research Institute, Hospital Clínic de Barcelona, Barcelona, Spain
*Purpose: Extracellular Vesicles (EVs) are membranous structures produced by cells which contain different cytoplasmic compounds and that have been described as potentially pathogenic elements in…
2021 American Transplant Congress
CHBP Induces Stronger Immunosuppressive CD127⁺ M-MDSC via Erythropoietin Receptor
C. Yang
Urology, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: Erythropoietin (EPO) is not only an erythropoiesis hormone, but also an immune regulatory cytokine. The receptors of EPO, (EPOR)2 and tissue protective receptor (TPR),…
2021 American Transplant Congress
Anti-CD272 Antibody (6B2) Generated Foxp3⁺Regulatory T Cells and Suppressed Donor Specific Antibody in Murine Cardiac Transplant Model
Y. Yamamoto¹, M. Uchiyama², K. Uchida³, H. Yagita³, M. Niimi¹
¹Department of Surgery, Teikyo University, Tokyo, Japan, ²Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan, ³Juntendo University, Tokyo, Japan
*Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…