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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Kidney Transplantation in Very Highly-Sensitized Patients with Maastricht Type III Non-heart-Beating Donors

    F. Villanego1, A. Mazuecos1, L. Vigara1, V. Lopez2, G. Bernal3, A. Rodriguez-Benot4, M. de Gracia5, P. Castro6, A. Alvarez6

    1Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, 2Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, 3Department of Nephrology, Hospital Virgen del Rocio, Sevilla, Spain, 4Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, 5Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, 6Andalusian Transplant Coordination, Sevilla, Spain

    *Purpose: In 2012, a kidney transplant (KT) program for very highly-sensitized (VHS) patients (PRA ≥ 95%) based on virtual crossmatch began in Andalusia (Spanish region).…
  • 2021 American Transplant Congress

    Waitlist and Post-Transplant Outcomes of Candidates With Lvad: Comparison of Old and New Heart Allocation Policies

    M. Colvin1, Y. Ahn2, S. Hall3, M. Walsh4, A. Israni2

    1Univ of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN, 3Baylor Univ, Dallas, TX, 4St. Vincent Heart Ctr, Indianapolis, IN

    *Purpose: The new heart allocation policy took effect in October 2018. Its risk stratification scheme prioritizes patients with short-term devices, raising concern that candidates with…
  • 2021 American Transplant Congress

    Prevalence and Dynamics of SARS-COV-2 IgG in Kidney Transplant Recipients

    Y. Al Azzi, P. Loarte, C. Pynadath, O. Alani, L. Liriano-Ward, M. Ajaimy, R. Bartash, J. Graham, M. Le, H. Yaffe, S. Greenstein, J. Rocca, M. Kinkhabwala, E. Akalin

    Montefiore Medical Center, New York, NY

    *Purpose: We aimed to investigate the prevalence and dynamics of SARS-CoV-2 IgG in kidney transplant recipients in the Bronx, New York, one of the epicenters…
  • 2021 American Transplant Congress

    Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients

    M. Pearl1, P. Weng1, A. Dokras2, H. Pizzo3, J. Garrison3, C. Butler1, J. Q. Zhang1, K. Lim3, E. Reed1, I. Kim3, M. Haas3, X. Zhang3, R. Ettenger1, S. Jordan3, D. Puliyanda3

    1Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, 2Pediatric Nephrology, UT South Western, Dallas, CA, 3Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA

    *Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
  • 2021 American Transplant Congress

    Allograft Discard Risk Index for Lung Transplantation

    R. M. Reul, G. Loor, P. S. Garcha, A. A. Rana

    Baylor College of Medicine, Houston, TX

    *Purpose: The demand for donor lungs continues to outpace the supply, yet nearly 80% of donor lungs consented for lung transplantation (LTx) are discarded.*Methods: We…
  • 2021 American Transplant Congress

    Can Procurement Biopsy Data Tell Us Anything? The Influence of Glomerulosclerosis on Long-term Kidney Graft Survival

    D. Stewart1, L. Kamal2, J. Foutz3, H. McGehee3, P. Saravanane2, S. Yu2, R. Yousfi2, G. Gupta2

    1United Network for Organ Sharing, Richmond, VA, 2Virginia Commonwealth University Health, Richmond, VA, 3Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Biopsy findings, particularly % glomerulosclerosis, have been shown to have a profound impact on kidney utilization decisions. Most studies of the association between procurement…
  • 2021 American Transplant Congress

    Incorporation of Donor Liver Macrovesicular Steatosis Into Srtr Risk Adjustment Models for Deceased Donor Yield and Post-Transplant Outcome

    A. Kwong1, C. Wang2, A. Wey3, N. Salkowski3, J. Snyder4, J. Wetmore2, A. Israni2, J. Lake4, P. Stock5, W. Kim1

    1Stanford University, Redwood City, CA, 2Medicine, Hennepin Healthcare, Minneapolis, MN, 3Scientific Registry of Transplant Recipients, Minneapolis, MN, 4University of Minnesota, Minneapolis, MN, 5University of California, San Francisco, San Francisco, CA

    *Purpose: The SRTR had not traditionally included biopsy results in post-transplant risk adjustment, yet biopsy results may influence outcomes and thus decisions regarding organ acceptance.…
  • 2021 American Transplant Congress

    The Impact of Covid-19 Pandemic on Living Donor Liver and Renal Transplantations in Japan: A Nationwide Survey

    S. Yamanaga1, T. Hibi2, R. Osawa3, K. Yuzawa4, H. Egawa5, K. Kuramitsu6

    1General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, 2Pediatric Surgery and Transplantation, Kumamoto University, Kumamoto, Japan, 3Infectious disease, Kameda medical center, Kamogawa, Japan, 4Transplant Surgery, Mito Medical Center, Higashiibaraki District, Japan, 5Gastrointestinal Surgery, Tokyo Women's Medical University Hospital, Shinjyuku-ku, Japan, 6HBP surgery, Kobe University, Kobe, Japan

    *Purpose: COVID-19 brought a huge impact on the field of organ transplantation. On 6th March, the Japan Society for Transplantation (JST) COVID-19 task force published…
  • 2021 American Transplant Congress

    Rabbit Anti-thymocyte Globulin Induction is Not Associated with Improved Outcomes in Liver Transplant Recipients

    P. Nguyen, N. Wilson, G. Saracino, R. Patel, S. K. Asrani, G. Testa, T. Sam

    Baylor University Medical Center, Dallas, TX

    *Purpose: Controversy remains on the role of rabbit anti-thymocyte globulin (rATG) induction for calcineurin inhibitor (CNI) delay after liver transplantation (LT). We examined the effect…
  • 2021 American Transplant Congress

    Cyp3a5 Extensive Metabolizer Phenotype May be Associated with an Increase in Class 2 Donor Specific Antibodies and Antibody-Mediated Rejection

    S. Mirza1, N. Wilson2, J. Van Zyl2, P. Nguyen2, T. Sam2, S. Hall2, M. Askar2, R. Patel2

    1Texas Tech Univeristy Health Sciences Center Jerry H. Hodge School of Pharmacy, Dallas, TX, 2Baylor University Medical Center at Dallas, Dallas, TX

    *Purpose: Tacrolimus (TAC) metabolism is highly dependent on CYP3A5, yet there is limited data on the effect of CYP3A5 genetic polymorphisms in heart transplant recipients…
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