Am J Transplant, Volume 21, Suppl 3 Archives - Page 36 of 139 - ATC Abstracts

2021 American Transplant Congress
Risk Factors Predicting Outcomes in Long-Term Pediatric Kidney Transplant Graft Survival
A. Anand, T. H. Malik, J. Dunson, M. F. McDonald, C. R. Christmann, N. Nguyen Galvan, C. O'Mahony, J. A. Goss, P. R. Srivaths, E. D. Brewer, A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: Pediatric kidney transplant recipients generally have good outcomes post-transplantation; however, the younger age and longer lifespan after transplantation in the pediatric population make understanding…
2021 American Transplant Congress
A Randomized, Multicenter, Blinded Study Assessing the Effects of Gaseous Nitric Oxide in an Ex Vivo System of Human Lungs
M. G. Hartwig¹, J. A. Klapper¹, N. Poola², A. Banga³, P. G. Sanchez⁴, J. S. Murala³, J. L. Potenziano²
¹Duke University Medical Center, Durham, NC, ²Mallinckrodt Pharmaceuticals, Bedminster, NJ, ³University of Texas Southwestern Medical Center, Dallas, TX, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The effects of nitric oxide (NO) on donor lungs during ex vivo lung perfusion (EVLP) have not been studied. We assessed whether the novel…
2021 American Transplant Congress
Significance of Repeated 1r Rejections in Heart Transplantation
C. Hsueh¹, L. Wilson², L. Bow², L. Bellumkonda²
¹Yale New Haven Hospital, New Haven, CT, ²Yale University School of Medicine, New Haven, CT
*Purpose: 1R rejection is commonly seen in routine post-transplant biopsies. While presence of occasional 1R rejection is not considered to be detrimental, the significance of…
2021 American Transplant Congress
The Evolution of the National Liver Review Board
S. Noreen¹, J. Trotter², J. Pomposelli³, M. Cafarella¹, J. Heimbach⁴
¹UNOS, Richmond, VA, ²BSWHealth, Dallas, TX, ³UCHealth, Aurora, CO, ⁴Mayo Clinic, Rochester, MN
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2021 American Transplant Congress
Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis
S. Yin, T. Song, Q. Zhong, T. Lin
Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China
*Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…
2021 American Transplant Congress
Machine Perfusion of Kidney Grafts in Simultaneous Liver Kidney Transplantation: National Trends and Outcomes
A. Chang¹, M. Chen¹, P. Abt¹, T. Bittermann²
¹Surgery, University of Pennsylvania, Philadelphia, PA, ²Gastroenterology, University of Pennsylvania, Philadelphia, PA
*Purpose: In this study we analyze the SRTR liver data set to determine the trends in machine perfusion of kidney grafts prior to SLK and…
2021 American Transplant Congress
ABCC2 Haplotypes Associations to Mycophenolic Acid Pharmacokinetics in Stable Renal Transplant Recipients
K. Tornatore¹, D. Brazeau², C. Meaney³, J. Consiglio⁴, A. Gundroo⁵, S. Chang⁶, G. Wilding⁴, L. Cooper³
¹Pharmacy Practice, School of Pharmacy; University at Buffalo- SUNY, Buffalo, NY, ²Pharmacy Practice, Marshall University, Huntington, WV, ³Pharmacy Practice, School of Pharmacy; University at Buffalo, Buffalo, NY, ⁴Biostatistics, School of Public Health; University at Buffalo, Buffalo, NY, ⁵Medicine, School of Medicine; Ohio State University, Columbus, OH, ⁶Medicine, School of Medicine; University at Buffalo, Buffalo, NY
*Purpose: Mycophenolic acid (MPA), exhibits interpatient pharmacokinetic (PK) variability attributed to enterohepatic circulation of the glucuronide metabolite (MPAG) to MPA. This is mediated by multidrug…
2021 American Transplant Congress
Kidney Paired Exchange in Children in the United-states
J. Hogan¹, A. G. Thomas², J. Verbesey³, D. L. Segev⁴
¹Transplant Research Center, Department of Surgery, Emory University, Atlanta, GA, ²Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ³Department of Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ⁴Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney paired exchange (KPE) plays an increasing role in the landscape of adult living donor transplant (LDTx) in the US. LDTx is the treatment…
2021 American Transplant Congress
Impact of Graft Quality on Patient Survival in Sick Patients
G. Handing¹, S. Keeling¹, C. Christmann¹, N. Galvan², C. O’Mahony², J. Goss², R. Cotton², A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Michael E DeBakey Department of Surgery, Division of Abdominal Transplant, Houston, TX
*Purpose: It is widely accepted in the literature that patients who have a Model for End Stage Liver Disease (MELD) Score greater than 30 incur…
2021 American Transplant Congress
Higher Number of Tacrolimus Dose Adjustments and Trough Level Measurements in Kidney Transplant Recipients with CYP3A5*1 Alleles
K. Reininger¹, G. Onyeaghala², T. Anderson-Haag¹, B. Wu², W. Guan², C. R. Dorr², R. Remmel², R. Mannon³, A. Matas², W. Oetting², A. Israni¹, P. Stahler¹, P. Jacobson²
¹Hennepin County Medical Center, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³University of Nebraska Medical Center, Omaha, NE
*Purpose: Tacrolimus (TAC) metabolism is dependent on the functional status of the cytochrome P450 family enzyme CYP3A5 which has three common loss of function (LoF)…