Am J Transplant, Volume 21, Suppl 3 Archives - Page 20 of 139 - ATC Abstracts

2021 American Transplant Congress
Cost Effectiveness Analysis Comparing Treatments of Biliary Strictures in Pediatric Liver Transplant Patients
B. Whitehead¹, C. Lemoine², R. Superina², J. Green³, S. Mohammad¹
¹Division of Gastroenterology, Hepatology and Nutrition, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ²Division of Transplant Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ³Division of Interventional Radiology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
*Purpose: Biliary strictures are associated with significant morbidity after pediatric liver transplantation. There are two main treatment options which are percutaneous transhepatic cholangiography (PTC) and…
2021 American Transplant Congress
Extracellular Matrix Injury of Kidney Allografts in Antibody-mediated Rejection
S. Clotet Freixas¹, C. McEvoy¹, I. Batruch², C. Pastrello³, M. Kotlyar³, J. Van¹, M. Arambewela¹, A. Boshart¹, S. Farkona¹, Y. Niu³, Y. Li¹, O. Famure¹, A. Bozovic⁴, V. Kulasingam⁴, P. Chen¹, J. S. Kim¹, E. Chan⁵, S. Moshkelgosha¹, S. A. Rahman⁶, J. Das⁶, T. Martinu¹, S. Juvet¹, I. Jurisica³, A. Chruscinski¹, R. John¹, A. Konvalinka¹
¹Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ²Department of Laboratory Medicine and Pathobiology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada, ³Krembil Research Institute, University Health Network, Toronto, ON, Canada, ⁴Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁵Department of Medicine, Division of Nephrology, University Health Network, Toronto, ON, Canada, ⁶Center for Systems Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: Antibody-mediated rejection (AMR) accounts for >50% of kidney graft losses. AMR is caused by donor-specific antibodies (DSA) against HLA and non-HLA antigens in glomeruli…
2021 American Transplant Congress
Superior Post-transplant Clinical Outcomes Using Portable Normothermic Perfusion and Assessment with the Organ Care System (ocs) Liver System: 1-year Outcomes of the Ocs Liver Protect Randomized Controlled Trial
J. Markmann¹, M. Abouljoud², M. Ghobrial³, C. Bhati⁴, S. Pelletier⁵, J. Magliocca⁶, T. Pruett⁷, A. Lu⁸, M. Rizzari⁹, S. Ottmann¹⁰, T. Klair¹¹, C. Eymard¹², G. Roll¹³, G. Reyes¹⁴, S. Black¹⁵, S. Florman¹⁶, S. Mirani¹⁷, C. Marsh¹⁸, G. Schnickel¹⁹, M. Kinkhabwala²⁰, A. Demetris²¹, H. Yeh²², P. Vagefi²³, M. MacConmara²³
¹MGH, Boston, MA, ²Henry Ford, Detroit, MI, ³Houston Methodist, Houston, TX, ⁴Virginia Commonwealth, Richmond, VA, ⁵UVA, Charlottesville, VA, ⁶Emory, Atlanta, GA, ⁷U. Minnesota, Minneapolis, MN, ⁸Tampa General, Tampa, FL, ⁹Henry Ford, Detriot, MI, ¹⁰Johns Hopkins, Baltimore, MD, ¹¹University of Texas HSC, San Antonio, TX, ¹²University of Tennessee HSC, Memphis, TN, ¹³UCSF, San Francisco, CA, ¹⁴U. Washington, Seattle, WA, ¹⁵Ohio State, Columbus, OH, ¹⁶Mt. Sinai, New York, NY, ¹⁷U. Nebraska, Omaha, NE, ¹⁸Scripps Clinic, San Diego, CA, ¹⁹U. San Diego, San Diego, CA, ²⁰Montefiore, New York, MA, ²¹UPMC, Pittsburgh, PA, ²²Massachusetts General Hospital, Boston, MA, ²³UT Southwestern, Dallas, TX
*Purpose: The OCS Liver PROTECT Trial was the first U.S. randomized controlled trial for liver perfusion and was designed to evaluate the impact of portable…
2021 American Transplant Congress
Prediction of Renal Allograft Tolerance by Machine Learning
Q. Fu¹, K. Deng², H. Yang¹, S. Deng¹, J. F. Markmann²
¹Organ Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Sciences and Technology of China, Chengdu, China, ²Center for Transplantation Sciences, MGH, Boston, MA
*Purpose: An ideal goal of transplantation is to withdraw or minimize immunosuppressants via the induction of tolerance to overcome drug toxicity, prolong allograft survival, and…
2021 American Transplant Congress
Depressive Symptoms and Listing for Kidney Transplantation
X. Chen, N. Chu, P. Sharma Basyal, W. Vihokrut, D. Crews, D. Brennan, S. Andrews, T. Vannorsdall, D. Segev, M. McAdams DeMarco
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Among patients with kidney failure, depressive symptoms are common and may be a barrier to completing the complex process of kidney transplantation (KT) evaluation…
2021 American Transplant Congress
Alpha 1-antitrypsin Reduces Cytokine Elaboration in a Xenogeneic Lung Transplantation Model
L. Burdorf¹, C. Laird², T. Zhang², M. R. Connolly¹, Z. Habibabady¹, S. Pratts¹, S. Miura¹, F. Pollok¹, W. Eyestone³, C. J. Phelps³, D. L. Ayares³, A. M. Azimzadeh¹, R. N. Pierson III¹
¹Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Surgery, University of Maryland, Baltimore, MD, ³Revivicor, Blacksburg, VA
*Purpose: Novel gene editing techniques have facilitated the generation of donor pigs with multiple genetic modifications, used for xenolung transplantation. Several rejection pathways, including antibody…
2021 American Transplant Congress
Outcomes of Kidney Transplantation from Hepatitis C Virus (HCV) Infected Donors Stratified by Recipient HCV Serostatus: A Mate Kidney Analysis
K. K. Sureshkumar¹, B. Chopra¹, R. L. McGill²
¹Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA, ²Nephrology, University of Chicago, Chicago, IL
*Purpose: Kidneys from donors infected with hepatitis C virus (HCV) are increasingly used for transplantation into HCV positive (+) recipients historically and into HCV negative…
2021 American Transplant Congress
Primary Uretero-ureterostomy in Renal Transplantation
H. Shokouh-Amiri¹, M. S. Naseer¹, D. Aultman¹, R. McMillan¹, S. Tandukar², F. T. Siskron³, N. Singh², G. Zibari¹
¹Advanced Surgery, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ²Transplant Nephrology, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA, ³Urology, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA
*Purpose: Uretero-neocystostomy (UN) is routinely performed in renal transplantation. Few studies of primary uretero-ureterostomy (UU) have been reported, showing its safety and feasibility. If the…
2021 American Transplant Congress
Kidney Programs Can Filter Off a Majority of Their Unwanted Organ Offers without Harming Transplant Volumes
A. Toll, H. McGehee, R. McTier, D. Stewart
Research, United Network for Organ Sharing, Richmond, VA
*Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: 34 centers…
2021 American Transplant Congress
Long Term Survival After Liver Transplantation for Advanced, Unresectable Intrahepatic Cholangiocarcinoma
R. R. McMillan¹, S. Kodali¹, M. Javle², A. Saharia¹, C. M. Mobley¹, M. J. Hobeika¹, A. Shetty¹, D. W. Victor¹, R. McFadden¹, M. Abdelrahim¹, K. Heyne¹, A. O. Gaber¹, R. M. Ghobrial¹
¹Houston Methodist Hospital, Houston, TX, ²MD Anderson Cancer Center, Houston, TX
*Purpose: Intrahepatic cholangiocarcinoma (ICCA) has traditionally been considered a contraindication to liver transplantation (LT). We previously reported a case series of six patients with large,…