Am J Transplant, Volume 21, Suppl 3 Archives - Page 20 of 139 - ATC Abstracts

2021 American Transplant Congress
Intrarenal B-cell Activating Factor (BAFF) Levels are Increased in Transplant Glomerulopathy
S. Panzer, K. Swanson, G. Pandya, L. Hidalgo, S. Reese
University of Wisconsin Madison, Madison, WI
*Purpose: Transplant glomerulopathy (TG), a key feature of chronic active antibody-mediated rejection (caABMR), is associated with allograft failure. B-cell activating factor (BAFF) is a cytokine…
2021 American Transplant Congress
Reassessing TCMR in Kidney Transplant Indication Biopsies: Emerging Evidence for Partial Exhaustion in Late TCMR
P. Halloran¹, J. Reeve¹, &. the INTERCOMEX Study Group²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: We rederived the MMDx rejection archetypes in an expanded set of 1679 kidney transplant biopsies to add power and potentially define heterogeneity in TCMR.…
2021 American Transplant Congress
Reduction in Hospitalizations and Deaths in Covid-19 Positive Abdominal Organ Transplant Recipients Following Implementation of A Protocol for Early Treatment with Bamlanivimab
A. Ahearn, T. Maw, J. Emamaullee, J. Kim, E. Blodget, J. Kahn, C. Goldbeck, L. Sher, Y. Genyk
Abdominal Transplantation, Keck Medical Center of USC, Los Angeles, CA
*Purpose: In December of 2020, our program was identifying up to twenty COVID-19 positive abdominal transplant recipients per week. After seeing our high hospitalization and…
2021 American Transplant Congress
Laminins Differentially Regulate Adaptive Alloimmune Responses
L. Li¹, M. Shirkey¹, W. Piao¹, Y. Xiong¹, V. Saxena¹, T. Zhang¹, J. Iyyathurai², R. Lakhan¹, R. Abdi³, J. Bromberg¹
¹Surgery, UMB, Baltimore, MD, ²CVID, UMB, Baltimore, MD, ³Harvard University, Boston, MA
*Purpose: Lymph node (LN) stromal cell expressed laminin α4 (Lama4) and laminin α5 (Lama5) fibers are associated with tolerance and immunity, respectively. They regulate cell…
2021 American Transplant Congress
CD40 Blockade by the Fc-Silent Immunosuppressive Antibody Iscalimab Results in Diminished B Cell Activation and Differentiation and is Paralleled by Whole Blood Gene Expression Data
R. Kraaijeveld¹, M. W. van den Hoogen¹, A. E. de Weerd¹, E. Ferroro², G. Robert², U. Laessing², B. Haraldsson², J. S. Rush², C. C. Baan¹
¹Erasmus MC, Rotterdam, Netherlands, ²Novartis Pharmaceuticals AG, Basel, Switzerland
*Purpose: Blockade of costimulatory molecule CD40 by the Fc-silent immunosuppressive drug Iscalimab has shown to inhibit acute alloreactivity in non-human primates and is currently being…
2021 American Transplant Congress
Clinical Value of Surveillance Biopsies in Pediatric Liver Transplantation: A Single Center Experience with >800 Biopsies
B. Rocque¹, A. Zaldana¹, C. Weaver², J. Huang¹, A. Barbetta¹, V. Shakhin², C. Goldbeck¹, G. Yanni², R. Kohli², Y. Genyk¹, J. Emamaullee¹
¹Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA, ²Pediatrics, Children’s Hospital-Los Angeles, Los Angeles, CA
*Purpose: While pediatric liver transplantation (LT) results in excellent long-term outcomes, a high incidence of early acute cellular rejection (ACR) and late graft fibrosis persists.…
2021 American Transplant Congress
Results of the Transplant Advance Practice Provider Survey: Opportunities for APPs to Contribute to Academic Pursuits
B. Muth¹, D. Krieger², N. McCormick³, M. Siegfired⁴, H. Domingo⁵, J. Yoo⁶, A. Frank⁷, K. Paolini⁸, A. Mayfield⁹, H. McDade⁹, A. Borth⁹, H. Hoy¹⁰
¹University of Wisconsin, Madison, WI, ²UCSF, San Francisco, CA, ³University of Colorado, Denver, CO, ⁴Swedish Organ Transplant, Seattle, WA, ⁵Northwestern, Chicago, IL, ⁶Rush, Chicago, IL, ⁷Medstar Georgetown University, Annandale, VA, ⁸Erie County Medical Center, Grand Island, NY, ⁹University of Maryland, Baltimore, MD, ¹⁰University of Alabama - Huntsville, Huntsville, AL
*Purpose: The pillars of academic medicine are research, education and patient care. While transplant Advance Practice Providers (APPs) are primarily recruited for clinical roles, many…
2021 American Transplant Congress
Change in Deceased Donor Demographics with Drug Intoxication Deaths: 2010 – 2019
D. Musgrove, D. Zaun, A. Israni, J. Snyder
SRTR, Minneapolis, MN
*Purpose: To understand the demographic change in deceased donor causes of death associated with drug intoxication, we explored trends over the 10-year period ending in…
2021 American Transplant Congress
A Fresh Look at Urbanicity and Its Impact on Additions to the Kidney and Liver Transplant Wait Lists
W. R. Johnson, S. A. Rega, I. D. Feurer, S. J. Karp
General Surgery, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Our aim is to examine the collective effects of social determinants of health (SDH) on kidney and liver wait list additions in the United…
2021 American Transplant Congress
The Relationship Between Health Literacy and Adverse Outcomes After Kidney Transplantation
E. Lorenz, T. Petterson, C. Schinstock, W. Sanchez, K. Yost
Mayo Clinic, Rochester, MN
*Purpose: Limited health literacy has been associated with a decreased likelihood of listing for transplant and an increased risk of waitlist mortality among kidney transplant…