2021 American Transplant Congress
Economic and Clinical Benefit of Cmv Matching in Kidney Transplantation
*Purpose: Recently, kidney transplant (KTx) centers in Oregon collaborated to preferentially allocate cytomegalovirus-seronegative (CMV D-) kidneys to seronegative recipients (CMV R-), successfully reducing high-risk CMV…2021 American Transplant Congress
Desensitization Using Clazakizumab® (anti-il-6) in Highly-hla Sensitized Patients Awaiting Kidney Transplant (nct03380962)
*Purpose: IL-6 is a critical cytokine for plasma cell IgG production. Clazakizumab (CSL Behring LLC) is a humanized monoclonal aimed at the cytokine IL-6. Here…2021 American Transplant Congress
Impact of Transplant Center Volume on Utilization of and Outcomes Following Donation After Circulatory Death Liver Transplantation in the United States
*Purpose: Despite increased utilization of donation after circulatory death (DCD) grafts in the US, impact of center volume on DCD liver transplantation (LT) remains unclear.…2021 American Transplant Congress
Liver Simulated Allocation Model Does Not Accurately Predict Organ Offer Decisions in Pediatric Liver Transplant Candidates
*Purpose: The U.S. relies on the Scientific Registry of Transplant Recipient’s (SRTR’s) Liver Simulated Allocation Model (LSAM) to predict the effect of allocation policy changes…2021 American Transplant Congress
Growing LDLT Volumes at a US Center- What Does It Take to Do Over 100 LDLTs Per Year
University of Pittsburgh, Pittsburgh, PA
*Purpose: LDLT remains underutilized in the US, accounting for2021 American Transplant Congress
Effective Patient Throughput on the Transplant Surgery Service
1UT Health San Antonio, San Antonio, TX, 2University Health, San Antonio, TX
*Purpose: Hospital bed capacity and patient throughput are persistent challenges for medical centers. One established strategy for increasing patient throughput and decompressing Emergency Departments is…2021 American Transplant Congress
The Role of Donor-derived Cell-free DNA to Detect Subclinical Acute Rejection in Kidney Allograft
*Purpose: We hypothesized that donor-derived cell-free DNA (dd-cfDNA) could detect subclinical acute rejection (subAR).*Methods: 429 blood samples paired with surveillance kidney biopsies from 208 patients…2021 American Transplant Congress
Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)
Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…2021 American Transplant Congress
Effect of HLA Class II Polymorphism on Predicted Cellular Immunity Against SARS-CoV-2 at the Individual Level and Within Twenty Five Race/ethnic Groups
*Purpose: Development of adaptive immunity after COVID-19 and after vaccination against SARS-CoV-2 is predicated on recognition of viral peptides, presented on HLA class II molecules,…2021 American Transplant Congress
TOLS are Novel Regulatory TLOs with A B Cell Signature
1Massachusetts General Hospital, Boston, MA, 2Co-Senior Authors, Boston, MA
*Purpose: Our previous studies suggest that a DBA/2 kidney graft is accepted by a MHC-fully mis-matched C57/BL6 recipient. Accepted renal allografts exhibited lymphoid like structures…
American Transplant Congress abstracts