ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Pregnancy Outcomes in 108 Heart Transplant Recipients

    L. A. Coscia1, A. Yusuf1, S. Rao2, S. Constantinescu3, M. J. Moritz4

    1Transplant Pregnancy Registry International, Philadelphia, PA, 2University of Virginia Heath System, Charlottesville, VA, 3Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 4Surgery, Lehigh Valley Health Network, Allentown, PA

    *Purpose: The purpose of this study was to describe 185 pregnancies in 108 heart transplant recipients.*Methods: Data regarding conceptions occurring between June 1987 and Dec…
  • 2021 American Transplant Congress

    Posttransplant Malignancy in HIV+ Kidney Transplant Recipients

    D. Sawinski1, R. Fitzsimmons1, J. Locke2, J. Trofe-Clark1, B. Shelton2, P. Reese1, E. Blumberg1

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Kidney transplant recipients and people living with HIV are both at increased risk for malignancy, including cancers that are virally-mediated. Despite the recognition of…
  • 2021 American Transplant Congress

    Oxalate Nephropathy After Kidney Transplant: Defining Histological Patterns, Contributing Factors and Graft Outcome

    N. Jakob1, A. Chuu1, J. Ninan1, E. Lim1, N. Zhang1, H. Amer2, F. Cosio2, H. Wadei3, M. Ryan1, C. Cortese3, L. Cornell2, M. Keddis1

    1Nephrology, Mayo Clinic, Scottsdale, AZ, 2Nephrology, Mayo Clinic, Rochester, MN, 3Nephrology, Mayo Clinic, Jacksonville, FL

    *Purpose: The objective of this study is to evaluate KTx recipients with biopsy proven oxalate nephropathy (ON) to better define risk factors, histologic patterns and…
  • 2021 American Transplant Congress

    Guiding Therapeutic Plasma Exchange for Amr Treatment in Lung Transplant Recipients Using Serial Dilution in Single Antigen Bead Assay

    O. A. Timofeeva1, J. Choe2, M. Alsammak2, E. J. Yoon2, S. Geier2, K. Carney2, J. Au2, A. Diamond2, J. A. Galli2, K. Shenoy2, A. Mamary2, S. Seghal2, P. Mullhal2, Y. Toyoda2, N. Shigemura2, F. Cordova2, G. Criner2, J. Brown2

    1MedStar Georgetown University Hospital, Washington, DC, 2Temple University Hospital, Philadelphia, PA

    *Purpose: Development of donor‐specific antibodies (DSA) is associated with poor outcomes in lung transplantation. Patients who are presented with at least probable AMR require treatment;…
  • 2021 American Transplant Congress

    The Impact of Combined Warm and Cold Ischemia Times on Post Transplant Outcomes

    M. E. Foley1, A. J. Vinson2, K. K. Tennankore2

    1Faculty of Medicine, Dalhousie University, Halifax, NS, Canada, 2Division of Nephrology, Medicine, Dalhousie University/ Nova Scotia Health, Halifax, NS, Canada

    *Purpose: Both prolonged warm ischemia time (WIT) and cold ischemia time (CIT) have been associated with an increased risk of graft failure following kidney transplantation,…
  • 2021 American Transplant Congress

    TIGIT Agonism Improves Immunosuppression of Cd8 T Cells by Ctla-4ig in a Treg Dependent Manner

    C. R. Hartigan, D. Liu, M. L. Ford

    Emory University Transplant Center, Emory University, Atlanta, GA

    *Purpose: Costimulation blockade therapeutics for immunosuppression in transplant are less toxic than calcineurin inhibitors offering improved graft longevity and patient quality of life, but belatacept-resistant…
  • 2021 American Transplant Congress

    Low Immunogenic Donors Improve Kidney Transplant Survival in Sensitized Recipients

    D. Bekbolsynov1, R. Green2, B. Mierzejewska1, M. Rees1, S. Stepkowski1

    1University of Toledo, Toledo, OH, 2Bowling Green State University, Bowling Green, OH

    *Purpose: Our previous results showed that low immunogenicity (IM) donors improved kidney allograft survival in non-sensitized recipients. Herein, we examined how the level of peak…
  • 2021 American Transplant Congress

    Evaluating Pneumocystis Jiroveci Pneumonia Prophylaxis in Lung Transplant Recipients

    J. Sharkey, K. McMurry, J. Park, C. Carlson, K. Gregg, D. Kaul, D. Lyu, L. Fitzgerald

    Michigan Medicine, Ann Arbor, MI

    *Purpose: The incidence of Pneumocystis jiroveci pneumonia (PJP) in lung transplant recipients (LTRs) on PJP prophylaxis is not well documented yet reported as high as…
  • 2021 American Transplant Congress

    Cardiac Risk Assessment in Liver Transplant Candidates: Survey of National Practice Patterns

    P. Barman1, R. Chadha2, L. VanWagner3

    1Div. of GI/Hepatology, University of California, San Diego, San Diego, CA, 2Anesthesiology, Mayo Clinic, Jacksonville, FL, 3Div. of GI/Hepatology, Northwestern University, Chicago, IL

    *Purpose: Cardiac disease is a leading cause of morbidity and mortality in the first year after liver transplantation (LT) and pre-transplant identification is vital to…
  • 2021 American Transplant Congress

    Resolution of Endothelial Inflammation is Delayed Following IFNγ, Which Provokes a Long-lasting Pro-adhesive Phenotype Dependent on JAK/STAT Signaling

    N. M. Valenzuela

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    *Purpose: Although many cytokines are upregulated within allografts undergoing rejection, intragraft transcripts are dominated by IFN-response signatures. Resolution is a key phase of inflammation needed…
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