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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction

    R. Winstead1, D. Kumar1, A. Brown1, I. Yakubu1, C. Song1, L. Thacker2, G. Gupta1

    1Virginia Commonwealth University Health, Richmond, VA, 2Virginia Commonwealth University, Richmond, VA

    *Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
  • 2021 American Transplant Congress

    Investigating Physician Outlook Regarding Living Donation Prior to Planned Withdrawal of Care

    S. Rath1, L. Washburn2, S. Creden1, M. Goss3, A. Rana1, J. Goss1, N. T. Galvan1

    1Baylor College of Medicine, Houston, TX, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3McGovern Medical School, Houston, TX

    *Purpose: The aim of this study is to assess the attitudes of physicians, physician assistants, and nurse practitioners in transplant and critical care regarding Living…
  • 2021 American Transplant Congress

    Short Term Outcomes in Previously Covid Positive Kidney Transplant Recipients in Pre-vaccine Era

    R. Prashar, N. J. Khoury, M. Ramesh, A. K. Patel

    Henry Ford Transplant Institute, Detroit, MI

    *Purpose: To study clinical characteristics and short-term outcomes in kidney transplant recipients who were previously infected with SARS-CoV-2*Methods: In this retrospective, single-center case-series, we identified…
  • 2021 American Transplant Congress

    Integrative Analyses of Circulating Small Rnas and Paired Kidney Graft Transcriptome in Transplant Glomerulopathy

    C. Kuscu1, K. Manjari2, M. Akram3, C. Kuscu4, A. Wolen,4, A. Bajwa4, J. Eason4, D. G. Maluf5, V. Mas6, E. Akalin7

    1Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, 2Department of Systems and Computational Biology, School of Life Sciences, University of Hyderabad,, Hyderabad,, India, 3Center for Biomedical Informatics, University of Tennessee Health Science Center, Memphis, TN, 4Surgery, James D Eason Transplant Institute, Memphis, TN, 5Surgery, Program in Transplantation, University of Maryland, Baltimore, MD, 6Surgery, Division Surgical Science, University of Maryland, Baltimore, MD, 7Medicine, Montefiore Medical Center, Abdominal Transplant Program, Albert Einstein College of Medicine,, NYC, NY

    *Purpose: Transplant glomerulopathy (TG) develops through multiple mechanisms including donor-specific antibodies, T cells and innate immunity. We investigate the role of circulating small RNAs (sRNAs)…
  • 2021 American Transplant Congress

    Kidney Transplantation in Very Highly-Sensitized Patients with Maastricht Type III Non-heart-Beating Donors

    F. Villanego1, A. Mazuecos1, L. Vigara1, V. Lopez2, G. Bernal3, A. Rodriguez-Benot4, M. de Gracia5, P. Castro6, A. Alvarez6

    1Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, 2Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, 3Department of Nephrology, Hospital Virgen del Rocio, Sevilla, Spain, 4Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, 5Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, 6Andalusian Transplant Coordination, Sevilla, Spain

    *Purpose: In 2012, a kidney transplant (KT) program for very highly-sensitized (VHS) patients (PRA ≥ 95%) based on virtual crossmatch began in Andalusia (Spanish region).…
  • 2021 American Transplant Congress

    Waitlist and Post-Transplant Outcomes of Candidates With Lvad: Comparison of Old and New Heart Allocation Policies

    M. Colvin1, Y. Ahn2, S. Hall3, M. Walsh4, A. Israni2

    1Univ of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN, 3Baylor Univ, Dallas, TX, 4St. Vincent Heart Ctr, Indianapolis, IN

    *Purpose: The new heart allocation policy took effect in October 2018. Its risk stratification scheme prioritizes patients with short-term devices, raising concern that candidates with…
  • 2021 American Transplant Congress

    Prevalence and Dynamics of SARS-COV-2 IgG in Kidney Transplant Recipients

    Y. Al Azzi, P. Loarte, C. Pynadath, O. Alani, L. Liriano-Ward, M. Ajaimy, R. Bartash, J. Graham, M. Le, H. Yaffe, S. Greenstein, J. Rocca, M. Kinkhabwala, E. Akalin

    Montefiore Medical Center, New York, NY

    *Purpose: We aimed to investigate the prevalence and dynamics of SARS-CoV-2 IgG in kidney transplant recipients in the Bronx, New York, one of the epicenters…
  • 2021 American Transplant Congress

    Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients

    M. Pearl1, P. Weng1, A. Dokras2, H. Pizzo3, J. Garrison3, C. Butler1, J. Q. Zhang1, K. Lim3, E. Reed1, I. Kim3, M. Haas3, X. Zhang3, R. Ettenger1, S. Jordan3, D. Puliyanda3

    1Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, 2Pediatric Nephrology, UT South Western, Dallas, CA, 3Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA

    *Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
  • 2021 American Transplant Congress

    Allograft Discard Risk Index for Lung Transplantation

    R. M. Reul, G. Loor, P. S. Garcha, A. A. Rana

    Baylor College of Medicine, Houston, TX

    *Purpose: The demand for donor lungs continues to outpace the supply, yet nearly 80% of donor lungs consented for lung transplantation (LTx) are discarded.*Methods: We…
  • 2021 American Transplant Congress

    Can Procurement Biopsy Data Tell Us Anything? The Influence of Glomerulosclerosis on Long-term Kidney Graft Survival

    D. Stewart1, L. Kamal2, J. Foutz3, H. McGehee3, P. Saravanane2, S. Yu2, R. Yousfi2, G. Gupta2

    1United Network for Organ Sharing, Richmond, VA, 2Virginia Commonwealth University Health, Richmond, VA, 3Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Biopsy findings, particularly % glomerulosclerosis, have been shown to have a profound impact on kidney utilization decisions. Most studies of the association between procurement…
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