Am J Transplant, Volume 21, Suppl 3 Archives - Page 108 of 139 - ATC Abstracts

2021 American Transplant Congress
Does the NSQIP-Transplant Experience Demonstrate That Obese Kidney Transplant Recipients are Still at Increased Risk for Surgical Site Infections?
H. C. Yaffe¹, A. K. Belli¹, J. R. Parekh², D. L. Sudan³, N. Elias⁴, K. D. Conzen⁵, D. P. Foley⁶, R. Hirose⁷, S. M. Greenstein¹
¹Surgery, Montefiore-Einstein Center for Transplantation, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, ²Surgery, University of California San Diego, San Diego, CA, ³Surgery, Division of Abdominal Transplant Surgery, Duke University Medical Center, Durham, NC, ⁴Surgery, Transplant Surgery Division, Massachusetts General Hospital, Boston, MA, ⁵Surgery, Division of Transplant Surgery, University of Colorado Hospital, Aurora, CO, ⁶Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁷Surgery, University of California San Francisco, San Francisco, CA
*Purpose: The National Surgical Quality Improvement Program for Transplant (NSQIP-T) was designed to track surgical outcomes in adult liver and kidney transplants (KTX). The Pilot…
2021 American Transplant Congress
Predicted Heart Mass Difference as a Risk Factor for Severe Primary Graft Dysfunction in the Contemporary Era of Heart Transplantation: A Report from the International Consortium on Primary Graft Dysfunction
F. Foroutan¹, L. K. Truby², Y. Moayedi¹, J. Han³, J. Guzman⁴, M. Farrero⁴, E. Baughan⁵, M. Farr⁵, H. Zafar⁶, J. Felius⁶, J. van Zyl⁷, D. Law⁸, S. Chih⁸, P. Angleitner⁹, M. Sabatino¹⁰, A. DeVore², R. J. Miller¹¹, L. Potena¹⁰, A. Zuckermann⁹, K. K. Khush³, S. A. Hall⁶, H. J. Ross¹
¹Ted Rogers Centre for Heart Research, Toronto, ON, Canada, ²Duke University School of Medicine, Durham, NC, ³Stanford University, Stanford, CA, ⁴Clinic Barcelona Hospital Universitari, Barcelona, Spain, ⁵Columbia University Medical Center, New York, NY, ⁶Baylor University Medical Center, Dallas, TX, ⁷Dallas University Medical Center, Dallas, TX, ⁸University of Ottawa Heart Institute, Ottawa, ON, Canada, ⁹Medical University of Vienna, Vienna, Austria, ¹⁰Bologna University Hospital, Bologna, Italy, ¹¹University of Calgary, Calgary, AB, Canada
*Purpose: Primary Graft Dysfunction (PGD) increases early mortality after heart transplant (HT). Predicted heart mass (PHM) difference may be a risk factor for PGD. Lack…
2021 American Transplant Congress
The Intersection of Cost, Quality, and Volume in Liver Transplant
D. Axelrod¹, R. Balakrishnan¹, A. Harris², S. Hohmann², J. Snyder³, B. Kasiske³, M. Schnitzler⁴, K. Lentine⁴
¹Univ of Iowa, Iowa City, IA, ²Vizient Inc., Irving, TX, ³SRTR, Minneapolis, MN, ⁴Saint Louis Univ, Saint Louis, MO
*Purpose: As a consequence of changing allocation practices and the ongoing shortage of high-quality organs, the cost of liver transplant (LT) continues to increase throughout…
2021 American Transplant Congress
Aligning Pediatric Waiting List and Post-Transplant Outcomes with the Adult Lung Allocation Score
M. Skeans¹, A. Wey¹, E. Lease², C. Lehr³, J. Alcorn⁴, R. Goff⁴, D. Stewart⁴, M. Valapour³
¹SRTR, Minneapolis, MN, ²Univ of Washington, Seattle, WA, ³Cleveland Clinic, Cleveland, OH, ⁴UNOS, Richmond, VA
*Purpose: Lung allocation is moving toward a continuous distribution framework (CDF), with components for waitlist (WL) urgency and post-transplant (PT) survival, as computed in LAS.…
2021 American Transplant Congress
The Microenvironment of Belatacept-Resistant Rejection
A. Johnson, J. Zhang, C. Larsen
Surgery, Emory University, Atlanta, GA
*Purpose: Belatacept is a co-stimulation blockade immunosuppressant, that despite demonstrating improved long-term outcomes, has not been widely adopted, in part, due to concern over early…
2021 American Transplant Congress
Quantifying Hidden Sensitization: HLA-reactive Memory B Cells in the Spleens of Sensitized Women
J. T. Killian¹, J. A. Houp¹, A. Nellore², R. G. King³, P. M. Porrett¹, F. E. Lund³
¹Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, ²Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, ³Department of Microbiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL
*Purpose: Measurement of circulating anti-HLA antibody (anti-HLA-Ab) in transplant candidates and recipients is required for successful organ transplantation. However, serum Ab measurement alone likely underestimates…
2021 American Transplant Congress
Harnessing Innate Lymphoid Cells to Prevent Graft-versus Host Disease
K. T. Reid¹, S. Q. Crome²
¹Immunology, University of Toronto, Toronto, ON, Canada, ²Ajmera Transplant Centre, TGHRI, University Health Network, Toronto, ON, Canada
*Purpose: Determine whether human innate lymphoid cells (ILCs) can be isolated, expanded and used in cell-based therapies to prevent Graft-versus Host Disease (GvHD) .*Methods: ILC2s…
2021 American Transplant Congress
Urinary Exosomal Cystatin C and Lipopolysaccharide Binding Protein as Biomarkers for Monitoring Antibody-mediated Rejection After Kidney Transplantation
M. Kim, S. Lim, S. Shin
Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of
*Purpose: This study aims to discover and validate urinary exosomal biomarkers for antibody-mediated rejection (ABMR) after kidney transplantation.*Methods: A total of 60 urine samples from…
2021 American Transplant Congress
P2X7 Receptor Activity Mediates Th17-Specific Self- and Alloreactivity in Non-Human Primates
C. Little, J. Sullivan, W. Burlingham, D. Kaufman
Department of Surgery, University of Wisconsin, Madison, WI
*Purpose: The broadly expressed ATP-binding purinergic receptor, P2X7 (P2X7R) is involved in the Th17 mediated cellular immune response to allo- and select self-antigens (Collagen type…
2021 American Transplant Congress
Donor T and NK Cells with a Special Tissue-Resident Memory Phenotype Migrate Into the Periphery of Lung Transplant Recipients – A Potential Feature for Tolerance Development
L. M. Ruhl¹, R. Bellmàs Sanz¹, A. Hitz¹, B. Wiegmann², K. A. Bläsing¹, W. Sommer², F. Ius², J. F. Kühne¹, A. Knöfel², L. M. Horn¹, I. Tudorache², A. Haverich², D. Jonigk³, G. Warnecke², C. S. Falk¹
¹MHH, Institute of Transplant Immunology, Hannover, Germany, ²MHH, Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover, Germany, ³MHH, Institute of Pathology, Hannover, Germany
*Purpose: After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the…