ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Circulatory Extracellular Vesicles from Lung Allograft Recipients with Chronic Lung Allograft Dysfunction Can Induce LKB1 Dependent Epithelial-Mesenchymal Transition

    M. Rahman, S. Angara, A. Arjuna, M. Smith, R. Bremner, T. Mohanakumar

    Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: Extracellular vesicles (EVs) play important role in physiological and pathological conditions. Recently we demonstrated that circulating exosomes (EVs) with lung self-antigens (SAgs) play important…
  • 2020 American Transplant Congress

    Trust and Transparency in Artificial Intelligence-Aided Immunosuppression Decisions

    J. Clement

    Information and Decision Sciences, University of Minnesota, Minneapolis, MN

    *Purpose: In transplant, there is significant interest in using Artificial Intelligence (including machine learning or predictive models) Clinical Decision Support Systems(AI CDSS). Properly designing and…
  • 2020 American Transplant Congress

    Physician Survey on Using APOL1 Genetic Testing in Live Kidney Donor Selection

    M. Doshi1, E. Gordon2, B. Freedman3, C. Thomas4, C. Glover5, J. Locke6

    1Medicine, University of Michigan, Ann Arbor, MI, 2Surgery, Northwestern University, Chicago, IL, 3Medicine, Wake Forest, Winston-Salem, NC, 4Medicine, University of Iowa, Iowa City, IA, 5N/A, Miami, FL, 6Surgery, University of Alabama, Birmingham, AL

    *Purpose: Live kidney donors of recent African ancestry are at an increased risk of developing end stage kidney disease than matched healthy non-donors. A recent…
  • 2020 American Transplant Congress

    Depletional Induction Improves Kidney Graft and Patient Survival in Recipients with a Previous Liver Transplant in the United States

    S. M. Riad1, N. Lim1, S. Jackson2, A. Matas3, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Induction choices for kidney-after-liver transplant recipients are variable. We examined the impact of kidney induction types on kidney graft and patient survival in liver…
  • 2020 American Transplant Congress

    Infectious Complications and Malignancy after Kidney Transplantation in the Elderly Population

    L. Liriano-Ward, M. Parides, Y. Al Azzi, C. Pynadath, M. Ajaimy, J. Graham, S. Greenstein, M. Kinkhabwala, J. Rocca, E. Akalin

    Montefiore Medical Center, Bronx, NY

    *Purpose: Kidney transplantation improves quality of life and survival in all patients regardless of age. However, older patients are prone to development of side effects…
  • 2020 American Transplant Congress

    Burnout and Professional Fulfillment among Pediatric Sold Organ Transplant Clinicians Pediatric Transplant

    C. Bogle1, M. K. Cousino Hood2, E. M. Fredericks3, J. Magee4, S. Warren1, E. Blume1

    1Advanced Cardiac Therapies, Boston Children's Hospital, Boston, MA, 2Pediatric Cardiology, C.S. Mott Children's Hospital, Ann Arbor, MI, 3Pediatric Psychology, C.S. Mott Children's Hospital, Ann Arbor, MI, 4Transplant, C.S. Mott Children's Hospital, Ann Arbor, MI

    *Purpose: Burnout has been associated with worse patient outcomes with increased medical errors and nosocomial infections as well as adverse effect on healthcare providers, such…
  • 2020 American Transplant Congress

    A Nonhuman Primate Model of Intestinal Transplantation – Technical Aspects and Early Outcomes

    R. Schmitz1, J. Yoon1, M. Song1, E. Jelly2, A. P. Wax2, S. J. Knechtle1, D. L. Sudan1, J. Kwun1

    1Department of Surgery, Duke University Medical Center, Durham, NC, 2Department of Biomedical Engineering, Duke University, Durham, NC

    *Purpose: Intestinal transplantation (IT) is the treatment of choice for patients with irreversible intestinal failure that experience complications from total parenteral nutrition. Long-term outcomes after…
  • 2020 American Transplant Congress

    The Effect of ANG-3777 on Hepatocyte Growth Factor Receptor C-MET Signaling

    L. Paka, I. D. Goldberg

    Angion Biomedica, Uniondale, NY

    *Purpose: Hepatocyte growth factor (HGF) regulates cell growth, development and tissue repair. HGF activity is mediated by the c-MET signaling pathway. The biological effects of…
  • 2020 American Transplant Congress

    Maintenance Steroids in the Setting of Alemtuzumab Induction Post-Kidney Transplant Increases Risk of Infection and Hospital Readmission

    A. R. Webb, A. A. Al-Bahou, A. J. Brueckner, A. T. Logan, R. S. Baliga, L. J. Bowman Anger

    Tampa General Hospital, Tampa, FL

    *Purpose: This study sought to assess the safety of steroid-containing maintenance immunosuppression in the setting of alemtuzumab (ALEM) induction.*Methods: Adult (>18 years) kidney transplant recipients…
  • 2020 American Transplant Congress

    Impact of Dialysis and Diabetes on Survival in Recipients of Combined Heart-Kidney Transplant

    J. Parekh1, H. Chau2, G. Schnickel2, J. Berumen2, K. Mekeel2

    1University of California, San Diego, La Jolla, CA, 2Surgery, University of California, San Diego, La Jolla, CA

    *Purpose: Mounting data shows a survival benefit of combined heart-kidney transplantation in patients with heart and renal failure. However, little has been done to understand…
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