Am J Transplant, Volume 20, Suppl 3 Archives - Page 28 of 223 - ATC Abstracts

2020 American Transplant Congress
Potential Benefits of Y-90 Radiation Microspheres for Bridging Liver Candidates with Hepatocellular Carcinoma to Liver Transplant
S. Pelletier¹, J. Durden², S. Shan², P. Vargas³, N. Goldaracena¹
¹University of Virginia Health System, Charlottesville, VA, ²School of Medicine, University of Virginia Health System, Charlottesville, VA, ³Department of Surgery, University of Virginia Health System, Charlottesville, VA
*Purpose: In October 2015, the UNOS policy for hepatocellular carcinoma (HCC) exception scores was changed to modify the maximum exception value and prolong the time…
2020 American Transplant Congress
Opioid Utilization Post-Operatively in Kidney Transplantation
S. Gattis, R. Badell
Emory Healthcare, Atlanta, GA
*Purpose: The Centers for Disease Control and Prevention has reported prescription opioid involved deaths increasing since the 1990s. National efforts are being made to fight…
2020 American Transplant Congress
Challenging Dogma That Anti-Thymocyte Globulin Induction with Delayed Calcineurin Inhibitor Benefits Patients with Renal Insufficiency Undergoing Heart Transplant
M. Kittleson, J. Patel, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, A. Shen, A. Velleca, L. Czer, F. Esmailian, J. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Anti-thymocyte globulin (ATG) induction is used in approximately 50% of heart transplant (HTx) patients in the United States to induce tolerance. Other programs only…
2020 American Transplant Congress
Kidneys from AKI Donors with Poor Long-Term Outcomes Present an Impaired Protein Expression for Cellular Stress and Repair
F. Neri¹, M. Lo Faro¹, C. Boffa¹, T. Surik¹, M. Kaisar¹, E. J. Sharples², J. P. Hunter¹, J. Lindeman³, R. Ploeg¹
¹Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom, ²Oxford Transplant Centre, Oxford, United Kingdom, ³Department of Vascular Surgery, Leiden University Medical Center (LUMC), Leiden, Netherlands
*Purpose: The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was…
2020 American Transplant Congress
A Monocyte-Derived MicroRNA Signature for Antibody-Mediated Rejection in Kidney Transplantation
C. Tinel¹, B. Lamarthée¹, F. Von Tokarski¹, M. Rabant², C. Legendre¹, W. Gwinner³, M. Naesens⁴, P. Marquet⁵, D. Anglicheau¹
¹Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Pathology, Necker Hospital, Paris, France, ³Nephrology, Hannover Medical School, Hannover, Germany, ⁴Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium, ⁵Nephrology, Dialysis and Transplantation, Inserm U850, Limoges University Hospital, Limoges, France
*Purpose: MicroRNAs (miRNAs) are small noncoding RNAs which regulate mRNA expression at the posttranscriptional level. We investigated blood miRNAs as non-invasive biomarkers in kidney transplantation…
2020 American Transplant Congress
Kidneys from Pediatric Donors Are Preferentially Allocated to Adult Highly Sensitized and Not to Pediatrics Under the New Kidney Allocation System (KAS)
D. Puliyanda¹, H. Pizzo¹, J. Garrison¹, S. Williamson², I. Kim², E. Huang²
¹Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: In 12/2014, the new Kidney Allocation System (KAS) assigned allocation priority to highly sensitized (HS) recipients while maintaining access to donors for pediatric patients…
2020 American Transplant Congress
Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) in Renal Allograft Biopsies (Bx) Are Beneficial to Clarifying ABMR Activity in Ambivalent Cases
H. Zhang¹, C. C. Nast², N. Ammerman³, A. A. Vo³, I. Gallegos³, M. Arevalo³, S. C. Jordan³, M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: “Thoroughly validated gene transcripts” in renal Bx was adopted as one of the criteria for ABMR diagnosis in the latest Banff classification. Here, we…
2020 American Transplant Congress
The Natural History of Waitlist Candidates in the United States
A. Massie¹, D. Segev²
¹Johns Hopkins School of Medicine, Baltimore, MD, ²Johns Hopkins, Baltimore, MD
*Purpose: Estimates of time to deceased-donor transplantation (DDKT) generally fail to take into account the competing risks of mortality. Understanding the natural history of KT…
2020 American Transplant Congress
Multi-Center, Open-Label Trial of Pre-Emptive Glecaprevir/Pibrentasvir (G/P) to Treat Recipients of Transplanted Kidneys from Deceased Donors with Hepatitis C Virus (MYTHIC)
M. Sise¹, D. Goldberg², J. Kort³, D. Schaubel⁴, R. Alloway⁵, C. Durand⁶, R. Fontana⁷, J. Friedewald⁸, R. Brown⁹, S. Prenner¹⁰, R. Landis⁴, P. Reese¹¹, R. Chung¹
¹Internal Medicine - Nephrology, MGH, Boston, MA, ²Hepatology and Transplantation, U Miami, Miami, FL, ³Abbvie, Chicago, IL, ⁴Department of Biostatistics, U Penn, Philadelphia, PA, ⁵Department of Internal Medicine - Nephrology and Hypertension, U Cincinnati, Cincinnati, OH, ⁶Department of Medicine, JHU, Baltimore, MD, ⁷Internal Medicine - Gastroenterology, U Michigan, Ann Arbor, MI, ⁸Internal Medicine - Nephrology and Hypertension, Northwestern, Chicago, IL, ⁹Internal Medicine - Hepatology, Weill Cornell, NYC, NY, ¹⁰Internal Medicine - Gastroenterology, U Penn, Philadelphia, PA, ¹¹Transplant Nephrology, U Penn, Philadelphia, PA
*Purpose: Kidneys from Hepatitis C virus (HCV)-infected deceased donors continue to be discarded at high rates despite small, successful studies of HCV-viremic donors into uninfected…
2020 American Transplant Congress
Outcomes of Heart Transplantation in Adults with Congenital Heart Disease Since UNOS Allocation System Change: UNOS Registry Analysis
P. Genyk, K. Yang, J. Nattiv, G. Liu, P. Banankah, P. Kingsford, J. Li, S. Nuno, K. Pandya, A. Vaidya, E. DePasquale
Department of Cardiology, Keck Medical Center of University of Southern California, Los Angeles, CA
*Purpose: We sought to examine the waiting list and post-HT outcomes in patients with congenital heart disease (CHD) within UNOS registry since the implementation of…