ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Outbreak of Pneumocystis Pneumonia in a Transplant Center Linked to a Single Genotype of Pneumocystis jirovecii: Effects of Cytomegalovirus Infection and Allograft Rejection

    S. Hosseini-Moghaddam1, S. Dufresne2, M. Shokoohi3, G. Singh1, E. HunterGutierrez1, P. Dufresne2, A. House1, P. Luke1, A. Nagpal1, P. Marotta1, A. Humar4, A. Jevnikar1, D. Kumar4

    1Western University,LHSC,University Hospital, London, ON, Canada, 2Maisonneuve-Rosemont Hospital,Université de Montréal, Montreal, QC, Canada, 3Epidemiology and Biostatistics, Western University, London, ON, Canada, 4University of Toronto, University Health Network, Toronto General Hospital, Toronto, ON, Canada

    *Purpose: Although post-transplant pneumocystis pneumonia (PCP) outbreaks have been reported from Asia, Australia and Europe, there are limited data from North America. We investigated transmissibility…
  • 2019 American Transplant Congress

    Daptomycin Perioperative Prophylaxis for Prevention of Vancomycin-Resistant Enterococcus Infection in VRE-Colonized Liver Transplant Recipients during the Early Post-Transplant Period

    S. Sarwar, S. Gleeson, M. Malinis, M. M. Azar

    Section of Infectious Diseases, Department of Medicine, Yale School of Medicine, New Haven, CT

    *Purpose: Antibiotic prophylaxis for enteric pathogens is recommended before liver transplantation (LT). Perioperative screening protocols and antimicrobials vary between institutions. Some institutions that do not…
  • 2019 American Transplant Congress

    Activation of Oxidative Stress-Adoptive Responses during Extended Ex Situ Heart Perfusion

    S. Hatami, X. Qi, M. Buchko, C. W. White, S. Bozso, S. Himmat, J. Nagendran, D. H. Freed

    Department of Surgery, University of Alberta, Edmonton, AB, Canada

    *Purpose: Cardiac function declines in a time-related fashion during ex situ heart perfusion (ESHP) regardless of ventricular load status. We have previously shown that the…
  • 2019 American Transplant Congress

    Metabolic Profiling of Steatotic Human Livers during Ex-Vivo Normothermic Machine Perfusion

    S. Raigani1, N. Karimian2, V. Huang2, S. Geerts2, S. Nagpal2, K. Uygun1, M. Yarmush1, H. Yeh1

    1Transplant Surgery, Massachusetts General Hospital, Boston, MA, 2Center for Engineering in Medicine, Shriners Childrens Hospital, Boston, MA

    *Purpose: Nearly 40-60% of discarded livers are due to steatosis because of poor recovery from ischemia-reperfusion injury and compromised post-transplant function. We evaluated steatotic (ST)…
  • 2019 American Transplant Congress

    Impact of a Novel Digital Medicine Program on Adherence and Utilization in Pediatric Transplant Patients

    S. Sullivan1, K. N. Triplett1, C. Sacks2, M. Tran2, D. M. Desai3

    1Solid Organ Transplant, Children's Medical Center, Dallas, Dallas, TX, 2Proteus Digital Health, Redwood City, CA, 3Transplant Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX

    *Purpose: Purpose: Optimal allograft function and long-term graft survival depends on many factors, including adherence to a complex medication regimen. Methods of measuring adherence are…
  • 2019 American Transplant Congress

    Patient Reported Side Effects Associated with Reduced Quality of Life after Living Donor Kidney Transplant

    J. Peipert, J. C. Caicedo-Ramirez, K. Ensor, J. Friedewald, M. Abecassis, D. Cella, D. Ladner, Z. Butt

    Northwestern University, Chicago, IL

    *Purpose: As living donor kidney transplant (LDKT) graft and patient survival approaches 100%, the focus of care turns to patient reported outcome measures such as…
  • 2019 American Transplant Congress

    Higher Post-Transplant CXCL13 Correlates with the Occurrence of Infection within 1 Year after Kidney Transplantation

    Y. Li1, Y. Li1, L. Yan1, L. Wang1, Y. Shi2, J. Tang1

    1Department of Laboratory Medicine/Research Centre of Clinical Laboratory Medicine, West China Hospital, Chengdu, China, 2Department of Nephrology, West China Hospital, Chengdu, China

    *Purpose: Chemokine is a subtype of cytokines that involved in the process of inflammation and immune responses, and play an important role in both kidney…
  • 2019 American Transplant Congress

    Pre-Transplant Ventricular Assist Device (VAD) Impacts Heart Transplant (HT) Survival

    M. S. Gharibdousti1, M. T. Khasawneh2, A. L Friedman3

    1Research, LiveOnNY, Manhattan, NY, 2Binghamton University, Binghamton, NY, 3LiveOnNY, Manhattan, NY

    *Purpose: Retrospective analysis of UNOS data was performed to determine regional variation in the utilization and impact of VAD prior to HT in the United…
  • 2019 American Transplant Congress

    Association Between Cumulative Pre-transplant Amiodarone Dose And Post-transplant Outcomes After Heart Transplantation

    K. Lang1, M. Sullivan2, P. Simone1, S. Patel1, L. M. Lourenco1

    1Pharmacy, University of Chicago Medicine, Chicago, IL, 2Pharmacy, Northwestern Medicine, Chicago, IL

    *Purpose: Previous studies have demonstrated a correlation between pre-transplant amiodarone use and post-operative bradycardia, primary graft dysfunction, and mortality in heart transplant (HT) recipients; this…
  • 2019 American Transplant Congress

    Infectious Risk of Rejection Therapy Following Heart Transplantation; Can It Be Avoided?

    M. Kittleson, J. Patel, S. Dimbil, R. J. Levine, G. Esmailian, A. Shen, T. Hage, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: The diagnosis of rejection after heart transplantation (HTx) is usually based on the surveillance endomyocardial biopsies (EMB). These protocol biopsies are performed at scheduled…
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