Am J Transplant, Volume 18, Suppl 3 Archives - Page 142 of 211 - ATC Abstracts

2018 American Transplant Congress
Excellent Long-Term Outcomes with Kidney Transplants from Deceased Donors with Acute Kidney Injury
G. Dube, S. Husain, D. Cohen, S. Mohan.
Medicine, Columbia University Medical Center, New York, NY.
Kidney transplants (KT) from donors with acute kidney injury (AKI; terminal creatinine ≥ 2.0) are increasingly performed and have similar short-term outcomes compared with KT…
2018 American Transplant Congress
Once-Daily MeltDose Tacrolimus Formulation and Renal Function in Caucasian Fast Tacrolimus Metabolizers: Does Early Identification Have an Impact in PK Sensitive Patients?
K. Budde,⁶ B. Suwelack,¹ D. Stevens,³ W. Du,⁴ C. Procaccianti,⁵ C. Maas,⁵ S. Bunnapradist.²
¹University Hospital of Münster, Münster, Germany; ²David Geffen School of Medicine at UCLA, Los Angeles; ³Veloxis Pharmaceuticals, Cary; ⁴Clinical Statistics Consulting, Norrystown; ⁵Chiesi Farmaceutici S.p.A., Parma, Italy; ⁶Charité Universitatsmedizin, Berlin, Germany.
Tacrolimus (TAC) nephrotoxicity can be seen even at low blood trough levels, with factors beyond trough levels potentially contributing. TAC fast metabolizers have higher Cmax,…
2018 American Transplant Congress
Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 9 Years Follow-Up
S. Narumi,¹ Y. Watarai,¹ N. Goto,² T. Hiramitsu,¹ M. Okada,¹ M. Tsujita,² K. Futamura,² M. Nishihira,³ T. Kobayashi.⁴
¹Transplant Surgery, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; ²Transplant Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; ³Nephrology, Masuko Memorial Hospital, Nagoya, Aichi, Japan; ⁴Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study was evaluated in…
2018 American Transplant Congress
Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study
M. Matignon,¹ C. Dudreuilh,¹ P. Rémy,¹ D. Desvaux,² P. Grimbert.¹
¹Nephrology Transplantation, APHP Henri Mondor, Creteil, France; ²Pathology, APHP Henri Mondor, Creteil, France.
IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
2018 American Transplant Congress
Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study
Y. Kim,¹ Y. Chiang,² S. Kim,³ M. Kim,⁴ S. Park,⁵ S. Wu,⁶ K. Horita,⁷ Y. Nakashima,⁷ H. Jiang,⁸ D. Han.¹
¹Asan Medical Center, Seoul, Korea; ²Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; ³Samsung Medical Center, Seoul, Korea; ⁴Severance Hospital, Seoul, Korea; ⁵Dongsan Medical Center, Daegu, Korea; ⁶Tri-Service General Hospital, Taipei City, Taiwan; ⁷Astellas Pharma, Inc., Tokyo, Japan; ⁸Astellas Pharma, Inc., Maao, Singapore.
A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
2018 American Transplant Congress
Making Right Donor Nephrectomy Great Again: Evaluating Right Hand Assisted Retroperitoneal Donor Nephrectomy
H. Alahdal,¹ F. Alghamdi,¹ M. Shoukri,² J. Brockmann,¹ D. Broering.¹
¹Kidney and Pancreas Transplantation, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; ²Cell Biology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Background: Living kidney transplant offers ideal therapy of end stage renal disease patients. A variety of minimal invasive techniques for donor nephrectomy have been described…
2018 American Transplant Congress
Analysis of Patient Reported Outcomes for Patients That Received Living Donor Kidney Transplants
E. Venniro,^1,2 J. Taylor.^1,2
¹Center for Transplantation, University of Rochester Medical Center, Rochester, NY; ²Division of Nephrology, University of Rochester Medical Center, Rochester, NY.
Purpose: Caring for subjective complaints is one of the most difficult aspects of any health care provider's job. These conditions in the transplant patient are…
2018 American Transplant Congress
Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience
M. Del Gaudio,¹ M. Ravaioli,¹ C. Zanfi,¹ V. Bertuzzo,¹ L. Maroni,¹ G. La Manna,² G. Liviano,² A. Siniscalchi,³ A. D'Errico,⁴ A. Pinna.¹
¹Organ Insufficency and Transplantation/Transplantation Unit Prof. A.D. Pinna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ²Organ Insufficency and Transplantation Nephrology Unit G. La Manna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ³Organ Insufficency and Transplantation Intensive Care Unit Prof. S. Faenza, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; ⁴Organ Insufficency and Transplantation Pathology Unit D'Errico, S.Orsola Malpighi Hospital University of Bologna, Bolgona, Italy.
One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)Methods: Ninety-three DKT…
2018 American Transplant Congress
Y-Adapter Mediated Next Gen Sequencing of BKPyV from Archived FFPE Tissue
E. Harake,¹ W. Wu,² J. Opp,² E. Farkash.¹
¹Pathology, Michigan Medicine, Ann Arbor; ²Michigan Medicine, Ann Arbor.
Background: In a subset of renal transplant recipients with urothelial carcinoma, tumor cells show universal expression of BK Polyomavirus (BKPyV) proteins, a hallmark of oncoviruses.…
2018 American Transplant Congress
Early Association of Low Doses of Tacrolimus and a mTOR Inhibitor in BK Polyomavirus Infection in Kidney Transplant Recipients
V. Lopez,¹ T. Vazquez,¹ C. Jironda,¹ M. Cabello,¹ E. Sola,¹ M. Leon,² E. Marques,¹ D. Hernandez.¹
¹Nephrology, Hospital Regional Malaga, Malaga, Spain; ²Pathology, Hospital Regional Malaga, Malaga, Spain.
Introduction: BK polyomavirus (BKV) replication can be detected in up to 60% of kidney transplant recipients, with an incidence of nephropathy of 5-10%, leading to…