ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Donor Leukocytes Are Eliminated by the Host's Immune System Shortly After Skin Transplantation in Mice.

    J. Marino, B. Gonzalez-Nolasco, G. Benichou.

    Center for Transplantation Sciences, Massachusetts General Hospital / Harvard Medical School, Boston, MA

    We have recently reported the lack of donor passenger leukocytes in the recipient's lymphoid organs of mice recipient of a skin allograft. On the other…
  • 2017 American Transplant Congress

    Prospective Monitoring of De Novo Donor-Specific Antibodies: Incidence, Clinical Outcomes and Dynamic Changes Over 5 Years After Kidney Transplantation.

    M. Ajaimy, A. Colovai, N. Hayde, J. Graham, M. Lubetzky, L. Kamal, G. De Bocardo, E. Akalin.

    Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, Bronx

    Background: We aimed to investigate the incidence and dynamic changes of de novo donor-specific-antibodies (dnDSA) after kidney transplantation and clinical outcomes.Methods: This is a prospective…
  • 2017 American Transplant Congress

    Risk of Kidney Rejection Following Simultaneous Liver Kidney Transplantation.

    S. Shah,1 A. Suddle,1 V. Aluvihare,1 O. Shaw,3 C. Shaw,1 N. Mamode,2 C. Callaghan,2 G. Koffman,2 N. Heaton.1

    1King's College Hospital, London, United Kingdom; 2Guy's and St Thomas' Hospital, London, United Kingdom; 3Viapath, London, United Kingdom

    Introduction: Simultaneous liver kidney transplant (SLK) recipients may be at risk of antibody-mediated kidney rejection (AMR) if the pre-transplant crossmatch is positive (+CXM). Accordingly, in…
  • 2017 American Transplant Congress

    Factors in Association with Sepsis Differ Between Simultaneous Pancreas/Kidney and Single Kidney Transplant Recipients.

    T. Schachtner,1,2,3 M. Zaks,1 A. Kahl,1 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; 3Charite and Max-Delbrück Center, Berlin Institute of Health BIH, Berlin, Germany

    As immunosuppressive therapy and allograft survival have improved in simultaneous pancreas/kidney transplant recipients (SPKTRs), the increased incidence of infection has become a major hurdle of…
  • 2017 American Transplant Congress

    Myeloid HO-1 Regulates M2 Macrophage Activation in Liver Ischemia-Reperfusion Injury (IRI).

    K. Nakamura,1 M. Zhang,2 S. Kageyama,1 B. Ke,1 R. Sosa,3 E. Reed,3 A. Zarrinpar,1 R. Busuttil,1 J. Araujo,2 J. Kupiec-Weglinski.1

    1Surgery, Liver Transplant, UCLA, Los Angeles, CA; 2Department of Medicine, UCLA, Los Angeles, CA; 3Department of Pathology, UCLA, Los Angeles, CA

    Background/Aim: Although anti-inflammatory macrophage differentiation (M2) from pro-inflammatory (M1) phenotype is critical for heme oxygenase-1 (HO-1) cytoprotection, the role of cell type-specific HO-1 induction remains…
  • 2017 American Transplant Congress

    Prolonged Liver Ischemia Triggers Necrotic Depletion of TIM4+ Kupffer Cells to Facilitate Tissue Inflammatory Immune Activation in Liver Ischemia-Reperfusion Injury.

    H. Wang,1 S. Yue,1 M. Ni,1 R. Busittil,1 J. Kupiec-Weglinski,1 L. Lu,2 Y. Zhai.1

    1Surgery, David Geffen School of Medicine, UCLA, Los Angeles, CA; 2Liver Surgery, The First affiliated Hospital of Nanjing Medical University, Nanjing, Jiansu Province, China

    Although mechanisms of immune activation against liver ischemia-reperfusion injury (IRI) have been studied extensively, questions regarding liver resident Kupffer cells vs. infiltrating macrophages (iM[Oslash]s) remain…
  • 2017 American Transplant Congress

    Predictive Value of Renal Transplant Scintigraphy for the Duration of Delayed Graft Function.

    S. Benjamens,1,2 R. Pol,1 A. Glaudemans,2 S. Berger,3 R. Slart.2

    1Surgery - Transplantation, University Medical Center Groningen, Groningen, Netherlands; 2Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands; 3Internal Medicine - Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands

    Background: Renal scintigraphy (RS) is a widely used test for the assessment of the transplanted kidney (KTX). As RS cannot reliably distinguish between rejection and…
  • 2017 American Transplant Congress

    Treatment of Post-Transplant Nephrotic Syndrome with Adrenocorticotropic (ACTH) Gel.

    A. Khalil,2 A. Karabala,1 A. Sharfuddin,2 M. Grafals.1

    1Medstar Georgetown Transplant Institute, Washington DC; 2Indiana University Health, Indianapolis

    Objectives: Post-kidney transplant proteinuria due to recurrent GN is considered to be a significant risk factor negatively affecting kidney transplant survival. In this case series…
  • 2017 American Transplant Congress

    Optimal Induction Therapy for Kidney Transplantation in Previous Heart Transplant Recipients: Analysis of OPTN/UNOS Registry.

    M. Sampaio, S. Hussain, B. Chopra, K. Sureshkumar.

    Nephrology, Internal Medicine, Allegheny General Hospital, Pittsburgh, PA

    It is unclear as to which induction agent is optimal for kidney transplant (KT) in prior heart transplant (HT) recipients who are already immunocompromised from…
  • 2017 American Transplant Congress

    Reduced Rituximab with Prophylactic Antibiotic Treatment Improves the Infectious Complications in Patients Undergoing ABO-Incompatible Living Donor Liver Transplantation.

    S.-C. Hsu, A. Thorat, L.-B. Jeng, H.-R. Yang, P.-C. Li, C.-C. Yeh, T.-H. Chen, K.-S. Poon.

    Organ Transplantation, China Medical University Hospital, Taichung, Taiwan

    Introduction:ABO incompatible (ABOi) living donor liver transplantation (LDLT) is a feasible alternative for donor liver allograft in emergency situations. The reported outcomes of ABOi-LDLT after…
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