ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Short- and Long-Term Graft Survival After Kidney Transplantation in Western Europe.

    M. Coemans,1 G. Verbeke, D. Anglicheau, O. Bestard, M. Giral, M. Naesens.1,2

    1Microbiology and Immunology, KU Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, KU Leuven, Leuven, Belgium

    Background: Improvement of kidney survival after transplantation has mainly been studied in the American population. There, it was found that improvement mostly occurred on the…
  • 2017 American Transplant Congress

    Post-Transplant Urinary Transglutaminase 2 Is a Potent Biomarker to Predict Kidney Allograft Inflammation or Fibrosis.

    S. Shin,1 Y.-M. Wee,1 M. Choi,1 Y. Cho,2 H. Go,2 Y. Kim,1 D. Han.1

    1Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 2Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

    Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. We tested the hypothesis that quantification of urinary…
  • 2017 American Transplant Congress

    Differential Effects of Immunosuppressive Drugs on DNA Methylation in T Cells.

    F. Peters,1 A. Peeters,1 L. Hofland,2 M. Betjes,1 K. Boer,1 C. Baan.1

    1Nephrology and Transplantation, Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands; 2Endocrinology, Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands

    Introduction The immune response after transplantation can be affected by DNA methylation – an epigenetic modification that regulates gene expression, including that of immune-related genes.…
  • 2017 American Transplant Congress

    Direct Intrahepatic Delivery of Pegylated-Catalase Is Protective in a Rat Ischemia-Reperfusion Injury Model.

    E. Beal,1 S. Black,1 J. Kim,1 V. Velazquez,2 K. Washburn,1 D. Hayes Jr.,3 B. Whitson.1

    1Department of Surgery, Division of Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Center for Vaccines and Immunity, The Research Institute at Nationwide Childrens Hospital, Columbus, OH; 3Departments of Pediatrics and Internal Medicine, The Ohio State University College of Medicine, Columbus, OH

    Introduction: Ischemia-reperfusion injury (IRI) is characterized by cessation of blood flow to an organ or tissue leading to accumulation of toxic metabolites and free radicals,…
  • 2017 American Transplant Congress

    Results of Stem Cell and Renal Transplantation in Patients with End Stage Renal Disease After Plasma Cell Dyscrasias.

    C. Moliz,1 B. Redondo,1 M. Molina,1 E. Morales,1 E. Gonzalez,1 J. Cabrera,2 A. Andres.1

    1Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain; 2Nephrology Department, Hospital Evangelico y Hospital Militar, Montevideo, Uruguay

    Introduction: Plasma cell dyscrasias (PCD) are a cause of end stage renal disease (ESRD). Traditionally, renal transplantation (RT) has been avoided in these patients due…
  • 2017 American Transplant Congress

    De Novo DSA Positivity Is Associated with a Higher Rate of Post-Transplant Bacterial and Viral Infections.

    A. Brooks,1 L. Rebellato,2 K. Briley,2 P. Bolin,2 S. Kendrick,3 A. Maldonado,4 C. Haisch,2 M. Everly.1

    1Terasaki Foundation Laboratory, Los Angeles; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC

    Background: BK viremia has been shown to correlate with de novo anti-HLA DSA (dnDSA) in renal transplant patients. However, it is unknown if and how…
  • 2017 American Transplant Congress

    Prevalence and Clinical Outcomes in Kidney Transplant Patients with Viral and Fungal Opportunistic Infections and Malignancy.

    M. Lubetzky, N. Hayde, L. Kamal, M. Ajaimy, P. Bedi, G. Deboccardo, E. Akalin.

    Montefiore Medical Center, Bronx

    Opportunistic infections and malignancy after kidney transplant (KTX) are associated with increased morbidity and mortality. We aimed to assess predictors and clinical outcomes in patients…
  • 2017 American Transplant Congress

    Does Histologic Grade in BK Polyoma Nephropathy Associate with Viral Load, Allograft Dysfunction or Allograft Loss? A Single Center Experience.

    M. Swee,1 S. Kuppachi,1 M. Fraer,1 P. Rastogi,2 P. Ten Eyck,1 M. Sanders.1

    1Nephrology, University of Iowa, Iowa City, IA; 2Pathology, University of Iowa, Iowa City, IA

    Purpose: BK polyoma nephropathy (BKPyN) is a well-recognized cause of allograft dysfunction and loss after kidney transplant. Despite increased recognition, it is unclear if changes…
  • 2017 American Transplant Congress

    Predicting Residual Renal Compensation in Living Kidney Donors Post-Donation.

    A. Diez, G. Diltz, J. Von Visger, U. Nori, T. Pesavento, R. Pelletier.

    Ohio State University College of Medicine, Columbus, OH

    In living kidney donors it is well established that post-donation the remaining kidney undergoes functional hypertrophy; resulting in a 20% – 40% in increase in…
  • 2017 American Transplant Congress

    α-Lipoc Acid Improve the Short Term Outcomes in Human Liver Transplantation.

    P. Casciato,1 N. Ambrosi,2 C. Fiorella,2 M. Vasquez,1 A. Gadano,1 M. de Santibañes,1 E. de Santibañes,1 M. Zandomeni,1 M. Chahdi,1 J. Laquinandi,1 P. Santofimia Castaño,3 J. Iovanna,3 E. Chuluyan,2 C. Incardona.4

    1Liver Transplantation Unit, Hospital Italiano, Buenos Aires, Argentina; 2CEFYBO, UBA-CONICET, Facultad de Medicina, Buenos Aires, Argentina; 3INSERM, Center of Research in Cancerology of Marseille (CRCM), Marseille, France; 4Fundación GADOR, GADOR, Buenos Aires, Argentina

    In liver transplantation (LT) the postreperfusion syndrome (PRS) is a serious intraoperative complication. The effect of α-lipoic acid (ALA) has not been evaluated. A double…
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