ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Outcomes of Kidney Transplantation After Primary, Repeat and Kidney After Nonrenal Solid Organ Transplantation: 10 Years UNOS Database Analysis.

    J. Ramirez,1 H. Aghil,1 M. Baz,3 B. Sawaya,1 N. Rajagopalan,2 X. Mei,3 R. Gedaly,3 A. El-Husseini.1

    1Division of Nephrology, University of Kentucky, Lexington, KY; 2Division of Cardiology, University of Kentucky, Lexington, KY; 3Division of Transplant Surgery, University of Kentucky, Lexington, KY

    Introduction: The aim of the study is to evaluate patient and kidney allograft survivals in primary, repeat, and kidney after nonrenal organ transplantation using national…
  • 2017 American Transplant Congress

    Prolonged Dialysis Prior to Renal Transplantation.

    D. Aufhauser Jr,1 A. Peng,1 D. Murken,1 S. Concors,1 M. Levine.1,2

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, Children's Hospital of Philadelphia, Philadelphia, PA

    Introduction: To increase access for patients with delayed transplant referral, the new Kidney Allocation System (KAS) recognizes waiting time from the earlier of dialysis initiation…
  • 2017 American Transplant Congress

    Inhibition of Multiple Nodes in the PI3K/Akt/mTOR Pathway Synergistically Suppresses Epstein-Barr Virus B Cell Lymphomas.

    A. Sang, G. Ivison, X. Qu, C. Esquivel, S. Krams, O. Martinez.

    Division of Abdominal Transplantation, Stanford School of Medicine, Palo Alto, CA

    Treating post-transplant lymphoproliferative disorders (PTLD) remains a clinical challenge due to adverse effects such as graft rejection. mTOR inhibitors, including rapamycin (RAPA), have shown both…
  • 2017 American Transplant Congress

    Outcomes from a Multinational Randomised Controlled Trial Comparing Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation.

    D. Nasralla,1 Consortium for Organ Preservation in Europe Liver Research Group,1 R. Ploeg,1 C. Coussios,2 P. Friend.1

    1Nuffield Department of Surgical Sciences, Oxford Transplant Centre, University of Oxford, Oxford, United Kingdom; 2Department of Biomedical Engineering, University of Oxford, Oxford, United Kingdom

    Introduction:By perfusing a liver with oxygenated blood, medications and nutrients at 37oC, normothermic machine perfusion (NMP) may improve outcomes after liver transplantation when compared with…
  • 2017 American Transplant Congress

    Activated Th1 and Th17 cTFH Phenotype Correlates with DSA Production in Kidney Transplant Recipients.

    C. Macedo, P. Fadakar, K. Hadi, B. Ellinof, A. Zeevi, S. Hariharan, D. Metes.

    University of Pittsburgh, Starzl Transplantation Institute, Pittsburgh

    Donor-specific anti-HLA antibodies (DSA) represent an important biomarker for acute rejection and are a major cause of long-term graft failure after kidney transplantation (KTx). The…
  • 2017 American Transplant Congress

    Blood Transfusion Before Organ Transplant: Patient Sensitization and Outcomes.

    I. Cich, K. Rudser, R. Brown, H. Ibrahim, R. Thorson, J. Patil, G. Loor, M. Hertz, C. Cohn.

    Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    BackgroundBlood transfusions (Btf) can cause alloimmunization to HLA antigens. Antibodies to HLA (HLAb) can increase patients' calculated panel reactive assay (cPRA) and make it more…
  • 2017 American Transplant Congress

    Dual Treatment of Suboptimal Doses of CsA and MSC Infusion Fully Prevents Acute Rejection in an Allogenic Model of Renal Transplantation.

    L. de Ramon,1 A. Merino,1 E. Ripoll,1 N. Bolaños,1 M. Gomà,3 J. Cruzado,1,2 J. Grinyó,1,2 J. Torras.1,2

    1Experimental Nephrology, IDIBELL-UB, Hospitalet Llobregat, Barcelona, Spain; 2Nephrology, Hospital Universitari de Bellvitge, Hospitalet Llobregat, Barcelona, Spain; 3Pathology, Hospital Universitari de Bellvitge, Hopitalet Llobregat, Barcelona, Spain

    The immunomodulatory characteristics of mesenchymal stem cells (MSCs) may lead to multifaceted strategies in rejection of organ transplantation. This study was designed to investigate the…
  • 2017 American Transplant Congress

    Complement Markers in Immunoadsorption Combined with Membrane Filtration.

    P. Malvezzi,1 F. Defendi,2 F. Eskandary,3 T. Jouve,1 L. Rostaing,1 C. Dumestre-Perard,2 G. Böhmig.3

    1Clinique de Néphrologie, CHUGA, Grenoble, France; 2Laboratoire d'Immunologie, CHUGA, Grenoble, France; 3Department of Medicine III, Medical University, Vienna, Austria

    Introduction: In HLA incompatible transplantation pretransplant desensitization is mandatory in order to eliminate the donor-specific alloantibody that might fix complement (C). In a randomized crossover…
  • 2017 American Transplant Congress

    Outcome After Living Donor Liver Transplantation for Hepatocellular Carcinoma in Elderly Patients > 65 Years: Assessing the Long Term Survival.

    A. Thorat, S.-C. Hsu, L.-B. Jeng, H.-R. Yang, P.-C. Li, C.-C. Yeh, T.-H. Chen, K.-S. Poon.

    Organ Transplantation, China Medical University Hospital, Taichung, Taiwan

    Background:In Asia, the hepatocellular carcinoma (HCC) is most common cancer. Despite of the surveillance most tumors are diagnosed at late stages and thus HCC continues…
  • 2017 American Transplant Congress

    Kidney Allograft Offers: Predictors of Turndown and the Relationship of Organ Acceptance Sequence to Kidney Allograft Survival.

    J. Cohen,1,2 J. Shults,2 D. Goldberg,2,3 D. Sawinski,1 P. Abt,4 P. Reese.1,2

    1Renal Division, University of Pennsylvania, Philadelphia, PA; 2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA; 3Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 4Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Background: There is growing interest in understanding patterns of organ acceptance and reducing organ discard. Little is known about how donor factors, holidays, and location…
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