ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    P-LKDPI: A Donor Risk Index for Pediatric Recipients of Living Donor Kidney Transplantation.

    A. Massie, N. Desai, A. Neu, D. Segev.

    JHU, Baltimore

    The Living Kidney Donor Profile Index (LKDPI) is used to assess risk of deceased donor kidneys for adult recipients based on donor characteristics. No comparable…
  • 2017 American Transplant Congress

    Financial Burden and Time to Returning to Work Among Living Kidney Donors.

    D. Larson, D. Berglund, D. Vock, A. Roman, J. Wiseman, H. Ibrahim, A. Matas.

    U of MN, Mpls

    Surveying our living kidney donor (LKD) population we learned (and reported) that: a) more than a quarter of our LKDs experienced substantial financial burden due…
  • 2017 American Transplant Congress

    Abrogating MyD88 Signaling in Donor Lung Resident Hematopoietic Cells Promotes Cell Based Tolerance Induction in Lung Allografts in Mice.

    Z. Zheng,1 J. Wang,1 X. Yeap,1 L. Li,3 L. Zhang,2 M. He,1 X. Luo,2 Z. Zhang.1

    1Comprehensive Transplant Center and Department of Surgery, Chicago, IL; 2Division of Nephrology and Hypertension, Chicago, IL; 3Department of Pathology, Chicago, IL

    Objectives: MyD88 signaling plays an important role in allograft rejection and tolerance induction. This study is designed to determine the cellular base of MyD88 expression…
  • 2017 American Transplant Congress

    Assessment of Islet Damage During Isolation Utilizing miRNAs and Its Significance with Post-Transplant Outcome in TPIAT.

    P. Saravanan,1 M. Kanak,2 G. Yoshimatsu,1 M. Lawrence,1 B. Naziruddin.3

    1Baylor Scott and White Research Institute, Dallas, TX; 2Virginia Commonwealth University, Richmond, VA; 3Baylor Simmons Transplant Institute, Dallas, TX

    Background: Pancreatic islets with high quality are essential for better endocrine function and post-transplant outcome in total pancreatectomy with islet autotransplantation (TPIAT). The islets are…
  • 2017 American Transplant Congress

    Post-Liver Transplant (LT) Early Allograft Dysfunction (EAD) Modulates the Effect of Pre-LT Kidney Function on Post-LT Survival.

    H. Wadei, M. Mai, B. Taner, K. Croome, A. Keaveny, L. Mai, D. Lee.

    Transplant, Mayo Clinic, Jackosonville, FL

    The impact of EAD on post-LT renal recovery remains unknown. Aim: To assess the impact of post-LT EAD on renal recovery and post-LT survival. Methods:…
  • 2017 American Transplant Congress

    Candidate Sex and Size Disparity in Liver Offer Acceptance.

    M. Bowring,1 A. Massie,1 C. Haugen,1 J. Ruck,1 D. Segev,1 S. Gentry.1,2

    1JHU, Baltimore; 2US Naval Academy, Annapolis

    Female liver transplant candidates face lower access to transplantation. Size match between the offered liver and the candidate is important but has not been considered…
  • 2017 American Transplant Congress

    Center Volume Does Not Influence the Risk Associated with Using High DRI Donor Livers.

    S. Black,1 E. Beal,1 K. Mumtaz,2 D. Hayes Jr.,3 A. El-Hinnawi,1 K. Washburn,1 D. Tumin.4

    1Department of Surgery, OSUWMC, Columbus, OH; 2Department of Internal Medicine, OSUWMC, Columbus, OH; 3Department of Internal Medicine, OSUWMC, Columbus, OH; 4Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH

    Background: High risk donor allografts potentially reduce survival after liver transplantation (LT), but increase access. We evaluated whether differences in patient mortality associated with using…
  • 2017 American Transplant Congress

    Addition of hEPCR.hCD55.hTFPI.hCD47 Modulates Multi-Lineage Cell Sequestration and Coagulation Activation by GalTKO.hCD46 Transgenic Pig Livers Perfused Ex Vivo with Human Blood.

    A. Cimeno,1 L. Burdorf,1 D. Parsell,1 C. Phelps,2 D. Ayares,2 A. Azimzadeh,1 R. Pierson III,1 R. Barth,1 J. LaMattina.1

    1Department of Surgery, University of Maryland, School of Medicine, Baltimore, MD; 2Revivicor, Inc., Blacksburg, VA

    PurposeThe sequestration of multiple hematopoietic cell lineages and inappropriate coagulation cascade activation is associated with poor outcomes in multiple liver xenotransplant models. Here we evaluate…
  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refuse to Accept DCD Kidney Offers.

    M. Bowring, A. Massie, D. Segev.

    JHU, Baltimore

    DCD kidneys provide survival benefit but continue to be declined and discarded at elevated rates. We aimed to characterize the potential benefit or harm associated…
  • 2017 American Transplant Congress

    Outcomes of Organs Transplants When the Donor Is a Prior Recipient.

    G. Lee,1 D. Goldberg,2 M. Levine,1 P. Abt.1

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Medicine, University of Pennsylvania, Philadelphia, PA

    Introduction: Organ scarcity continues to limit the field of transplantation, which leads to death for patients on waiting lists. Organs from “Organ Donors After Transplant”…
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