ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    U.S. Outcomes in Early Liver Transplantation for Alcoholic Hepatitis: Results from the American Consortium of Early Liver Transplantation for Alcoholic Hepatitis (ACCELERATE-AH).

    B. Lee,1 N. Mehta,1 L. Platt,2 G. Im,3 G. Therapondos,4 H. Han,5 D. Victor,6 D. Dronamraju,7 I. Hanouneh,8 M. Voigt,9 M. Rinella,10 S. Eswaran,11 J. Hause,11 C. Hsu,12 J. Dodge,1 Z. Li,2 N. Terrault.1

    1UCSF, SF; 2Johns Hopkins, Baltimore; 3Mt Sinai, NYC; 4Ochsner, New Orleans; 5USC, LA; 6Houston Methodist, Houston; 7Maryland, Baltimore; 8Cleveland Clinic, Cleveland; 9Iowa, Iowa City; 10Northwestern, Chicago; 11Rush, Chicago; 12UPenn, Philadelphia

    INTRODUCTIONA Franco-Belgian protocol showed that early liver transplant (LT) in severe alcoholic hepatitis (AH) could improve survival with low incidence of alcohol relapse (AR). Application…
  • 2017 American Transplant Congress

    Risk Factors and Consequences of De Novo Anti-HLA Donor Specific Antibodies in Kidney Transplant Recipients: The Force Awakens.

    B. Javaid, S. Rosen-Bronson, D. Li, M. Awwad, A. Gilbert, S. Ghasemian, J. Verbesey, P. Abrams, M. Grafals, J. Fenton, C. Cannon, J. Rapisura, J. Moore, M. Cooper.

    Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC

    Background: Presence of anti-HLA donor specific antibodies (DSAs) has been associated with inferior kidney transplant outcomes. Identification of risk factors for de novo DSAs could…
  • 2017 American Transplant Congress

    Development of De Novo Donor Specific Antibodies (dnDSAs) Not the Presence of Pre-Transplant Donor Specific Antibodies (Pre-DSAs) Increase Rejection Risk in Crossmatch Negative Kidney Transplant Recipients.

    H. Khamash, L. Archambault, M. Buras, H. Kosiorek, M. Pando, K. Reddy, B. Kaplan, R. Heilman.

    Mayo Clinic Arizona, Phoenix, AZ

    Aim: Study the impact of Pre-DSAs on allograft outcomes in crossmatch negative kidney transplant recipients.Methods: Single center retrospective analysis of characteristics and outcomes of kidney…
  • 2017 American Transplant Congress

    Timing of Mesenchymal Stem Cell Infusions Affects Rejection Free and Overall Islet Allograft Survival.

    N. Kenyon,1 M. Willman,1 D. Han,1 A. Rabassa,1 W. Diaz,1 R. Leeman,1 K. McHenry,2 D. Salomon,3 A. Bartholomew,4 N. Kenyon,1 D. Berman.1

    1Diabetes Research Institute, University of Miami, Miami, FL; 2University of Illinois at Urbana-Champaign, Champaign, IL; 3The Scripps Research Institute, La Jolla, CA; 4University of Illinois at Chicago, Chicago, IL

    We recently demonstrated that autologous, bone marrow-derived mesenchymal stem cells (MSC) promote allogeneic islet engraftment and survival in a streptozotocin induced, cynomolgus monkey model of…
  • 2017 American Transplant Congress

    Assessing the Impact of the New KAS on Transplant Rates in Highly-HLA Sensitized (HS) Patients After Desensitization (Des) 2 Years Post Implementation.

    A. Vo,1 S. Williamson,1 K. Myers,1 E. Huang,1 J. Choi,1 X. Zhang,2 A. Peng,1 R. Najjar,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; 2HLA Laboratory, Cedars-Sinai Medical Center, LA, CA

    Introduction: The new KAS aims to improve access to transplantation for HS patients, specifically CPRA 99-100%. Our center has extensive experience w. DES to improve…
  • 2017 American Transplant Congress

    Effect of Embolization History and Tumor Treatment Response on Plasma TGFβ in HCC Patients Listed for Liver Transplantation.

    P. Thevenot,1 K. Núñez,1 J. Gonzalez-Rosario,1 T. Sandow,1 A. Alharbi,1 A. Bokhari,1 D. Wyczechowska,2 A. Ochoa,2 A. Cohen.1

    1Multi-Organ Transplant Institute, Ochsner Health System, New Orleans, LA; 2Stanley S Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA

    Purpose: TGFβ signaling is an integral pathway in hepatocellular carcinoma (HCC) metastasis. In this study, we monitored TGFβ levels and imaging response in HCC patients…
  • 2017 American Transplant Congress

    Is There Any Difference Between ABO-Incompatible and ABO-Compatible Liver Transplantation? Oncologic Aspect.

    J. Lee,1 J. Lee,1 S. Song,1 S.-K. Kwon,1 D. Kim,1 J. Lee,2 M. Kim,1 G. Choi,1 J. Choi,1 D. Han,1 S. Kim,1 D. Joo.1

    1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; 2Department of Surgery, CHA University, Bundang, Korea

    Introduction: Liver transplantation (LT) is increasing treatment option for hepatocellular carcinoma (HCC) in East Asia. Over-immunosuppression is risk factor for oncologic outcome after transplantation and…
  • 2017 American Transplant Congress

    Lack of Utility of KDPI in Dual Kidneys from Donors at the Extremes of Age.

    D. Felts, M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, W. Doares, S. Kaczmorski, R. Stratta.

    Transplant, Wake Forest Baptist Health, Winston-Salem, NC

    The study purpose was to analyze outcomes in recipients of pediatric dual en bloc (EB) kidneys from small pediatric donors (SPDs, age ≤ 3 years)…
  • 2017 American Transplant Congress

    Reliability of Donor Kidney Biopsies from Time of Organ Recovery Compared to Immediate Post-Reperfusion Biopsies.

    M. Barrett, A. Prater, E. Farkash, D. Christopher, D. Fritze, N. Matusko, R. Sung, K. Woodside.

    University of Michigan, Ann Arbor

    Frozen section or rapid permanent biopsies of donor kidneys are frequently obtained for higher risk kidneys. We sought to investigate agreement between the procurement donor…
  • 2017 American Transplant Congress

    Quantitative Gene Expression Analysis of CRM-Panel Genes Using FFPE Kidney Tissues for Transplant Injuries.

    T. Sigdel, M. Nguyen, D. Dobi, S.-C. Hsieh, J. Liberto, F. Vincenti, M. Sarwal, Z. Laszik.

    University of California San Francisco, San Francisco

    Background: A common immune response module (CRM) of 11 genes was identified to define acute rejection (AR) through meta-analyses of 1030 different engrafted tissues including…
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