2017 American Transplant Congress
The mTOR Signal Regulates Myeloid Derived Suppressor Cells Differentiation and Immunosuppressive Function in Acute Kidney Injury.
Urology, Zhongshan Hospital, Fudan University, Shanghai, China
The mammalian target of rapamycin (mTOR) is a serine–threonine kinase that senses various environmental stimuli. The mTOR signal controls innate and adaptive immune response in…2017 American Transplant Congress
A Novel Equation, GRAIL (GfR Assessment in Liver Disease) Correctly Classifies Patients with Reduced GFR and Predicts Development of ESRD.
1BUMC, Dallas, TX; 2USC, LA, CA; 3NW, Chicago, IL
Estimating glomerular filtration rate(CKD-EPI, MDRD-4, MDRD-6) is poor in liver patients with renal dysfunction(GFR<30ml/min). We developed a model for GFR Assessment In Liver disease(GRAIL) before…2017 American Transplant Congress
IdeS, an IgG Endopeptidase, Effectively Cleaves Anti-CMV IgG, Resulting in Inhibition of Antibody (Ab)-Mediated NK Cell Activation in Kidney Transplant Patients (KTX Pts).
Background: Viral infections represent significant morbidity factors for KTx Pts. Ab-dependent cell-mediated cytotoxicity (ADCC) is a major pathway to eliminate virally infected cells and is…2017 American Transplant Congress
Microcirculation Inflammation in Kidney Allograft Biopsies.
Introduction: The Microcirculation Inflammation (IM) in kidney transplants is a strong predictor of graft loss inde-pedent of C4d and donor specific antibody(DSA)ObjetiveAnalysis of kidney allograft…2017 American Transplant Congress
Naïve and Interferon-gamma Activated Mesenchymal Stem Cells Differentially Affect Immune Responses In Vitro and In Vivo.
We have observed interferon gamma-treated autologous mesenchymal stem cells (MSC) to rapidly ex vivo expand CD3+CD4+CD25- T cells to >80% CD3+CD4+C25+FoxP3+ T regulatory cells with…2017 American Transplant Congress
Outcomes of 100 ABO Incompatible Kidney Transplants: A Single US Center Experience.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
IntroductionAcceptable patient and graft outcomes of ABO incompatible (ABOi) living donor kidney transplantation (LDKT) have been reported with the use of desensitization strategies. Data on…2017 American Transplant Congress
Incidental Hepatocellular Carcinoma in Explanted Livers: An Assessment After LIRADS Introduction.
1Surgery, Washington University, St. Louis, MO; 2Radiology, Washington University, St. Louis, MO
Background: Despite new technologies and improvements in imaging diagnosis, incidental and misdiagnosed hepatocellular carcinomas (HCC) are entities that remain present and problematic in liver transplantation.Methods:…2017 American Transplant Congress
HCC and Cardiac Cirrhosis After the Fontan Procedure in a Patient with Congenital Heart Disease and Situs Inversus.
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
Introduction. Hypoplastic left heart syndrome (HLHS) is a fatal congenital cardiac anomaly for which surgical palliation is needed, the Fontan procedure. HLHS accounts for <5%…2017 American Transplant Congress
Outcomes of Kidney Transplantation Using Deceased Diabetic Donors.
Introduction: Histological reversal of diabetic lesions in transplanted kidney once euglycemia has been restored is well documented. Conversely, it is known that diabetes status in…2017 American Transplant Congress
Urinary Renal Progenitors Isolation: A Novel Predictor of Kidney Graft Outcome.
1Hospital Univ Bellvitge, Barcelona, Spain; 2Meyer's Children Hosp, Firenze, Italy
Background: Longterm kidney allograft outcomes remain as unmet need. Most studies focus on mechanisms of graft injury, and kidney reparative mechanisms are neglected. Isolation of…
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