ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Tenofovir Use Is Not Associated with Reduced Bone Density or Fractures in Liver Transplant Recipients.

    N. Lim, C. Engler, J. Lake.

    University of Minnesota, Minneapolis, MN

    BackgroundTenofovir disproxil fumarate (TDF) and reduced bone density in the HIV population is well-documented. The effect of TDF use on bone density in patients who…
  • 2017 American Transplant Congress

    Statins in Liver Transplant Recipients: Rates of Use, Mortality and Rejection.

    R. Selim,1 A. Abdulhamid,1 A. Shyamraj,2 A. Watson,2 J. Tang,2 S.-M. Jafri.2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI

    Introduction:Liver transplant recipients are prone to developing metabolic syndrome following transplant, likely secondary to immunosuppressant use. Among those with metabolic syndrome, the rate of cardiovascular…
  • 2017 American Transplant Congress

    Living Donor Liver Transplantation for Alcoholic Liver Disease.

    H. Braun, J. Dodge, J. Roberts, N. Ascher.

    University of California, San Francisco, San Francisco, CA

    The literature on living donor liver transplantation (LDLT) for alcoholic liver disease (ALD) is sparse. We report our experience w/LDLT for ALD at a single,…
  • 2017 American Transplant Congress

    Effect of Statins on Influenza Vaccine Antibody Concentrations in Lung Transplant Recipients.

    A. Condon,1 C. Garmoe,2 M. Hayney.2

    1Department of Pharmacy, UW Health, Madison, WI; 2School of Pharmacy, University of Wisconsin, Madison, WI

    Background: Large population studies have shown that statin use at the time of influenza immunization is associated with lower antibody concentrations and decreased vaccine efficacy.…
  • 2017 American Transplant Congress

    Inflammation, Impaired Energy Metabolism and Synthetic Failure Characterize the Liver Transcriptome of End-Stage Idiopathic Pediatric Acute Liver Failure (PALF).

    M. Ningappa,1 P. McKiernan,2 R. Squires,2 Q. Sun,1 B. Higgs,1 K. Soltys,1 G. Bond,1 C. Ashokkumar,1 G. Mazariegos,1 R. Sindhi.1

    1Pediatric Abdominal Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background: PALF requiring liver transplantation (LTx) often has no known etiology, and could result from undiagnosed metabolic disorders. Mitochondrial dysfunction is common in PALF, but…
  • 2017 American Transplant Congress

    Ornithine Transcarbamylase Deficiency (OTC) in the Donor Liver, the Importance of Ascertaining the Cause of Death in the Brain Dead Donor.

    M. George,1 G. Thomas,1 A. Shun,1 M. Stormon.2

    1Paediatric Surgery and Transplant Surgery, Children's Hospital at Westmead, Sydney, NSW, Australia; 2Paediatric Gastroenterology, Children's Hospital at Westmead, Sydney, NSW, Australia

    The importance of ascertaining the cause of brain death in the donor is vital . We present a case of cadaveric liver donation (seg 2…
  • 2017 American Transplant Congress

    Ex vivo Expanded Regulatory T cells Combined with Short-Term Costimulation Blockade Prevent Rejection of Vascularized Composite Allografts.

    B. Oh, G. Furtmüller, M. Iglesias, M. Fryer, P. Akre, D. Cooney, W. Lee, G. Raimondi, G. Brandacher.

    Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    [Background] Reconstructive transplantation represents a valid therapeutic option after devastating tissue loss. Routine clinical application, however, is hampered by the toxicity of long-term maintenance immunosuppression.…
  • 2017 American Transplant Congress

    Effects of Tofacitinib (JAK-3 Inhibitor) on De Novo HLA-A2 Antibody Production in a Mouse Model of Allo-Sensitization.

    N.-N. Chai, G. Wu, I. Kim, A. Klein, S. Jordan.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Purpose: Tofacitinib is a Janus Kinase Inhibitor currently approved by FDA for treatment of rheumatoid arthritis. In considering its effect in reducing B cell proliferation…
  • 2017 American Transplant Congress

    Brain-Dead Donors Terminal Inflammation Is Associated to Delayed Graft Function in Kidney Transplant Recipients.

    D. Cucchiari,1 D. Fritz,2 V. Pedro,2 A. Ramon,3 P. David,3 R. Jordi,2 O. Frederic,2 R. Ignacio.2

    1Renal Transplant Unit, Hospital Clínic, Barcelona, Spain; 2Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Barcelona, Spain; 3Transplant Coordination Unit, Hospital Clínic, Barcelona, Spain

    BACKGROUND: in kidney transplantation recipients, increased biomarkers of systemic inflammation before and after the transplant are associated to worse short- and long-term renal outcomes. However,…
  • 2017 American Transplant Congress

    Three Induction Therapies on Patients with Delayed Graft Function After Kidney Transplantation, a Three-Year Outcome Analysis.

    A. Umber, M. Killackey, A. Paramesh, B. Alper, F. Teran, A. Baudy, Y. Liu, J. Buell, R. Zhang.

    Departments of Medicine and Surgery, Tulane University School of Medicine, New Orleans, LA

    We compare the 3-year outcomes of induction therapies with either methylprednisolone (group 1, n=58), basiliximab (group 2, n=56) or alemtuzumab (group 3, n=98) in primary…
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