ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Clinical Impact of Strength and Class of Pre transplant Donor Specific Antibody on Kidney Transplant Recipient Receiving Steroid Free Maintenance Immunosupression Regimen.

    O. Adebiyi, O. Simo, S. Hussain, D. Mishler, W. Goggins, T. Taber, A. Sharfuddin, M. Yaqub.

    Renal Transplant, Indiana University School of Medicine, Indianapolis, IN

    Background: The class and strength of pre- transplant DSA has been described as playing a role in determining future risk of acute rejection (AR) and…
  • 2017 American Transplant Congress

    Optimization of Extended-Release Tacrolimus Dose with Mycophenolate Mofetile Based Immunosuppression in De Novo Kidney Transplant Recipients: 2 Years Outcome.

    Y. Watarai,1 S. Narumi,1 M. Okada,1 R. Kimura,1 K. Hatazoe,1 K. Futamura,1 T. Yamamoto,1 T. Hiramitsu,1 M. Tsujita,1 N. Goto,1 T. Kobayashi.2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; 2Kidney Transplant Surgery, Aichi Medical University, Nagakute, Aichi, Japan

    Purpose: Once-daily tacrolimus extended-release formulation (TACER) has been accepted in kidney transplantation, however its optimal dosing are not well determined. We have validated the institutional…
  • 2017 American Transplant Congress

    Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.

    D. Hesselink,1 L. Andrews,2 B. de Winter,2 J. Tang,3 N. Shuker,2 R. Bouamar,2 R. van Schaik,4 B. Koch,2 T. Van Gelder.1

    1Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus MC, Rotterdam, Netherlands; 3Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China; 4Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands

    Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…
  • 2017 American Transplant Congress

    Integrated Magnetic-Electrochemical Exosome (iMEX) Technology to Detect Rejection in Kidney Transplant Recipients.

    J. Assaker, J. Park, S. Routray, S. Eskandari, H. Lee, J. Azzi.

    Transplantation Research Center, Harvard Medical School, Boston; Exosome Diagnostic Inc, Cambridge

    Methods for monitoring clinical rejection including increases in serum creatinine and urinary protein excretion may not reflect subclinical rejection. Similarly repeat biopsy may result in…
  • 2017 American Transplant Congress

    Myocardial Improvement Six Months After Kidney Transplantation: Non-Contrast Cardiac Resonance Study.

    M. Contti, L. Morales-Buenrostro, H. Nga, P. Garcia, M. Barbosa, H. Takase, M. da Silva, A. Moyses.

    Internal Medicine, Botucatu School of Medicine, Botucatu, Sao Paulo, Brazil

    INTRODUCTION: Patients with stage 5 chronic kidney disease (CKD) are at increased risk of cardiovascular disease, considering left ventricular hypertrophy (LVH) an independent risk for…
  • 2017 American Transplant Congress

    Serum Phosphorus and Cardiovascular Disease Outcomes, Graft Failure, or Total Mortality in Chronic Kidney Transplant Recipients.

    B. Merhi,1 T. Shireman,2 M. Carpenter,3 J. Kusek,4 P. Jacques,5 M. Pfeffer,6 A. Levey,7 M. Rao,7 J. Kim,8 J. Ix,9 A. Bostom.1

    1Medicine, Rhode Island Hospital, Chepachet, RI; 2Gerontology, Brown Uinversity, Chepachet, RI; 3Public Health, UNC, Chapel Hill, NC; 4NIDDK, National Institutes of Health, Bethesda, MD; 5Nutritional Epidemiology, Tufts Human Nutrition Research Center, Boston, MA; 6Medicine, Brigham and Women's Hospital, Boston, MA; 7Medicine, Tufts New England Medical Center, Boston, MA; 8Medicine, Toronto General Hospital, Toronto, ON, Canada; 9Medicine, Veterans Administration Medical Center, San Diego, CA

    Mild hyperphosphatemia may be present in chronic kidney transplant recipients [KTRs]. Limited data are available from large, multicenter KTR cohorts assessing the potential relationships between…
  • 2017 American Transplant Congress

    Donor Creatinine and Graft Outcomes in Pediatric Kidney Transplant Recipients.

    N. Hayde, M. Del Rio.

    Montefiore Medical Center, Bronx, NY

    Background: The role of donor peak and terminal creatinine on short and long term allograft outcomes in pediatric kidney transplant recipients is unclear.Aim: To determine…
  • 2017 American Transplant Congress

    Urinary Proteomics to Diagnose Chronic-Antibody-Mediated Rejection in Pediatric Kidney Transplantation.

    N. Kanzelmeyer, P. Zürbig, H. Mischack, K. Heindl Ruszai, T. Seemann, M. Hansen, M. Henn, A. Fichtner, B. Toenshoff, A. Melk, L. Pape.

    Pediatric Nephrology, Hannover Medical School, Hannover, Germany; Mosaiques Diagnostics, Hannover, Germany; Pediatric Nephrology, University Hospital of Vienna, Vienna, Austria; Pediatric Nephrology, University Hospital of Prague, Prague, Czech Republic; KfH Center for Pediatric Nephrology, Leipzig, Germany; Pediatrics I, University Hospital of Heidleberg, Heidleberg, Germany

    Chronic antibody-mediated rejection (cAMR) is the main cause of long-term graft loss and presents a diagnostic challenge in renal transplantation medicine. Late-stage diagnosis is made…
  • 2017 American Transplant Congress

    Restrictive Approach to Simultaneous Liver Kidney Transplantation.

    S. Sultan, S. Fitzpatrick, T. Kozlowski, S. Malik, S. Hanish, D. Bruno, M. Weir, W. Hutson, R. Barth, J. LaMattina.

    Surgery, University of Maryland School of Medicine, Baltimore

    Purpose: MELD based allocation and “Share 35” policy implementation has resulted in an overall increased incidence of renal failure at the time of liver transplantation,…
  • 2017 American Transplant Congress

    Course of Inflammatory Bowel Disease Activity in Primary Sclerosing Cholangitis Patients Undergoing Liver Transplantation.

    R. Parekh,1 M. Segovia,2 N. Kaur.1

    1Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI; 2Gastroenterology and Hepatology, Duke University Medical Center, Durham, NC

    Aim: Primary sclerosing cholangitis (PSC) is associated with inflammatory bowel disease (IBD). We aimed to review disease activity of IBD in patients with PSC undergoing…
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