ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Renoprotective Effects of Carbon Monoxide–Releasing Molecule 3 in Ischemia Reperfusion Injury and Cisplatin-Induced Toxicity.

    Y. Yoon,1 H. Lee,1 K. Huh,2 M. Kim,2 S. Kim,2 Y. Kim,2 W. Han.1

    1Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Background: We investigated the effects of a soluble carbon monoxide–releasing molecule (CORM) in cisplatin-induced cytotoxicity and ischemia reperfusion injury (IRI) in vitro.Methods: The effects of…
  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    Determinants of Successful Use of Sirolimus in Renal Transplantation.

    M. Naik,1 W. Gwinner,2 W. Arns,3 E. Basic,10 K. Budde,1 F. Diekmann,4 M. Fischereder,5 J. Goßmann,6 K. Heller,7 N. Heyne,8 J.-S. Jürgensen,1 C. Morath,9 U. Riester.10

    1GSSG, Berlin, Germany; 2GSSG, Hannover, Germany; 3GSSG, Köln, Germany; 4GSSG, Barcelona, Spain; 5GSSG, München, Germany; 6GSSG, Frankfurt, Germany; 7GSSG, Erlangen, Germany; 8GSSG, Tübingen, Germany; 9GSSG, Heidelberg, Germany; 10GSSG - Pfizer, Berlin, Germany

    Sirolimus (SLR) is an established component in the immunosuppressive treatment after renal transplantation.The side effects of SLR differ from other immunosuppressants and may limit its…
  • 2017 American Transplant Congress

    Effect of Everolimus on the Cardiac Function in Kidney Transplant Recipients.

    K. Tsujimura,1 M. Ota,1 H. Ishida,2 K. Tanabe.2

    1Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan; 2Urology, Kidney Center, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan

    PURPOSE: In this study, we evaluated the effect of everolimus (EVR), one of the mammalian targets of rapamycin on cardiac function in kidney transplant recipients.METHODS:We…
  • 2017 American Transplant Congress

    Soluble Human Leukocyte Antigen-G Levels and Prolonged Allograft Survival: A Demographic Analysis.

    C. Callaway,1 A. Ajith,2 V. Portik-Dobos,2 P. Best,3 C. Zayas,3 R. Kapoor,3 A. Horuzsko,2 L. Mulloy.3

    1Medical College of Georgia, Augusta University, Augusta, GA; 2Georgia Cancer Center, Augusta University, Augusta, GA; 3Section of Nephrology, Department of Medicine, Augusta University, Augusta, GA

    Human leukocyte antigen-G (HLA-G) is a tolerogenic protein shown to contribute to allograft survival. Dimerized, soluble HLA-G (sHLA-Gd) has been shown to significantly prolong allograft…
  • 2017 American Transplant Congress

    Everolimus Reduces Carotid Intima-Media Thickness in Renal Transplant Recipients After One Year: Randomized Controlled Trial.

    P. Garcia, H. Takase, H. Nga, M. Contti, J. Hueb, L. Morales-Buenrostro.

    Internal Medicine, Botucatu Medical School - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

    Cardiovascular disease remains the commonest cause of death in kidney transplant recipients. Although some studies suggest that Mammalian target of rapamycin (mTOR) inhibitors may reduce…
  • 2017 American Transplant Congress

    The Clinical Significance of Red Cell Distribution Width (RDW) in Kidney Transplant Recipients.

    S. Park,1 J. Ha,1 Y. Kim,1 H. Lee,1 Y. Kim,1 C. Lim,1 I. Jung,1 D.-J. Han,2 S.-K. Park,2 Y. Kim,2 J. Lee.1

    1Seoul National University College of Medicine, Seoul, Korea; 2Asan Medican Center, Seoul, Korea

    Background Increased red cell distribution width (RDW) has been known to be associated with worse prognosis in various populations. Although the levels of RDW are…
  • 2017 American Transplant Congress

    Single Kidney Transplantation from Pediatric Donors Younger Than 3 Years to Adult Recipients.

    L. Zhu, B. Liu, S. Chang, D. Du, N. Gong, J. Jiang, Z. Chen, G. Chen.

    Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Background: Traditionally, the criteria of splitting pediatric en bloc kidneys for transplantation into two adults includes: donor age > 3 years, donor weight > 12kg,…
  • 2017 American Transplant Congress

    The Effect of Transplant Center Volume on Survival Outcomes for Patients Listed for Simultaneous Liver and Kidney Transplantation.

    R. Modi,1 D. Tumin,2 E. Beal,3,4 D. Hayes Jr.,4,5 J. Hanje,4,6 A. Michaels,4,6 K. Washburn,3,4 L. Conteh,4,6 S. Black,3,4 K. Mumtaz.4,6

    1Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH; 2Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH; 3General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH; 4Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH; 5Pulmonary Medicine, Nationwide Children's Hospital, Columbus, OH; 6Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH

    This study examines the effect of center volume on survival differences between Simultaneous Liver Kidney Transplantation (SLKT) and liver transplantation alone (LTA).Methods: The United Network…
  • 2017 American Transplant Congress

    Delayed Calcineurin Inhibitor Introduction and Long Term Renal Outcomes in Liver Transplant Recipients Receiving Basiliximab Induction.

    N. Lange,1,2 D. Salerno,1 C. Sammons.2

    1Department of Pharmacy, Weill Cornell Medical Center, New York, NY; 2Department of Pharmacy, Columbia University Irving Medical Center, New York, NY

    BACKGROUND Basiliximab may be used to delay the initation of calcineurin inhibitors (CNI) in patients with renal injury after liver transplantation (LT). The optimal time…
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