Am J Transplant, Volume 17, Suppl 3 Archives - Page 22 of 181 - ATC Abstracts

2017 American Transplant Congress
Interruption of RAAS in Hypertensive Proteinuric Kidney Donors.
O. Sanchez,¹ L. Ferrara,¹ D. Berglund,¹ A. Matas,² R. Foley,¹ H. Ibrahim.¹
¹Department of Internal Medicine, U of MN, Mpls, MN; ²Department of Surgery, U of MN, Minneapolis, MN
The aim of this analysis was to assess the progression of eGFR between proteinuric hypertensive living kidney donors (HTN-LKDs) receiving ACE inhibitors (ACEinh) or angiotensin…
2017 American Transplant Congress
Prognostic Histopathologic Characteristics in Recurrent IgA Nephropathy: The Clinical Significance of Vascular Change.
S. Park, H. Cho, M.-Y. Yu, Y. Kim, K. Moon, Y. Kim, H. Lee.
Seoul National University Hospital, Seoul, Korea
Background Although recurrent IgA nephropathy (IgAN) after kidney transplantation is known to cause lgraft failure, the clinical significance of histopathologic parameters in allografts needs further…
2017 American Transplant Congress
The Incremental of Cost of Incompatible Living Donor Kidney Transplant: A National Cohort Analysis.
D. Axelrod,¹ K. Lentine,² M. Schnitzler,² H. Xiao,² X. Lou,³ B. Orandi,³ J. Garonzik Wang,³ A. Massie,³ D. Segev.³
¹Surgery, East Carolina University, Greenville, NC; ²Transplant, Saint Louis University, St. Louis, MO; ³Surgery, Johns Hopkins University, Baltimore, MD
Incompatible living donor kidney transplant (ILDKT) has been established as an effective option for patients with willing but human leukocyte antigen incompatible live donors, reducing…
2017 American Transplant Congress
Multi-Stakeholder Perspectives on the Importance of Outcomes for Trials in Kidney Transplantation: An International Best Worse Scaling Survey.
M. Howell,^1,2 N. Evangelidis,^1,2 B. Sautenet,² G. Wong,^1,2,3 J. Craig,^1,2 K. Howard,¹ A. Tong.^1,2
¹School of Public Health, University of Sydney, Sydney, Australia; ²Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia; ³Centre for Transplant Research, Westmead Hospital, Sydney, NSW, Australia
To optimize the benefits of kidney transplantation, recipients and clinicians should have an agreed, shared management plan. This relies on prioritizing the same outcomes but…
2017 American Transplant Congress
EXPANDER-1: Exploring Renal Transplants Using Hepatitis-C Infected Donors for HCV-Negative Recipients.
C. Durand, D. Brown, R. Wesson, N. Bhair, F. Naqvi, D. Ostrander, M. Bowring, A. Massie, S. Rasmussen, J. Sugarman, D. Segev, M. Sulkowski, N. Desai.
JHU, Baltimore, MD
Kidneys from hepatitis C-infected (HCV+) donors are underutilized in an era of severe organ shortage. In an effort to expand the donor pool, we evaluated…
2017 American Transplant Congress
TACI Polymorphisms Associated with De Novo Alloantibodies in Humans and Allograft Rejection in Mice.
J. Platt,¹ E. Farkash,² A. Lefferts,¹ M. Samaniego,³ M. Cascalho.¹
¹Surgery, University of Michigan, Ann Arbor, MI; ²Pathology, University of Michigan, Ann Arbor, MI; ³Internal Medicine, University of Michigan, Ann Arbor, MI
A. Trans-membrane Activator and CAML Interactor (TACI) controls B cell differentiation and memory and exists as numerous allelic variants among healthy individuals and individuals with…
2017 American Transplant Congress
Minimal Effect of Broader Heart Sharing on Regional Outcomes.
A. Bitar,¹ M. Skeans,² R. Davies,³ M. Farr,⁴ A. Kao,⁵ L. Robbins-Callahan,⁶ J. Rogers,⁷ S. Silvestry,⁸ M. Colvin.^1,2
¹U of MI, Ann Arbor, MI; ²SRTR, Mpls, MN; ³Nemours/AIDHC, Wilmington, DE; ⁴Columbia U, NY, NY; ⁵Mid-America Heart Inst, KC, MO; ⁶UNOS, Richmond, VA; ⁷Duke U, Durham, NC; ⁸FL Hosp Transplant Inst, Orlando, FL
The OPTN/UNOS Heart Subcommittee proposed a revision to policy 6 (Allocation of Hearts and Heart-Lungs) to better address heart transplant candidate medical urgency. They developed…
2017 American Transplant Congress
Outcomes of Protocol Allograft Kidney Biopsy in DeNovo Donor Specific Antibodies.
S. Parajuli, P. Reville, T. Ellis, A. Djamali, D. Mandelbrot.
University of Wisconsin, Madison, WI
There is limited information about the role of protocol kidney biopsies for de-novo donor specific antibodies (dnDSA) in kidney transplant recipients (KTR). We initiated monitoring…
2017 American Transplant Congress
HLA-C Mismatching and Humoral Alloimmune Responses in Pediatric Kidney Recipients with Subclinical Vascular Injury.
M. Seifert, M. Yanik, V. Hauptfeld-Dolejsek, R. Mannon.
University of Alabama at Birmingham, Birmingham, AL
Background: Antibodies to mismatched donor HLA antigens (DSA) have been associated with poor long-term outcomes in adult kidney recipients. We recently demonstrated a high prevalence…
2017 American Transplant Congress
High Regulatory T Cells Rate Early After Lung Transplantation Is Associated with Bronchiolitis Obliterans Syndrome Development.
M. Durand,^1,2 P. Lacoste,^2,3 C. Brosseau,^1,3 E. Durand,³ J. Loy,³ K. Henrio,^2,3 R. Danger,¹ P. Royer,³ A. Fourreau,³ A. Magnan,^3,4 S. Brouard.¹
¹INSERM U 1064, Center for Research in Transplantation and Immunology (CRTI), Nantes, France; ²Université de Nantes, Nantes, France; ³UMR INSERM 1087 CNRS 6291, Institut du Thorax, Nantes, France; ⁴Service de Pneumologie, Institut du Thorax, Nantes, France
Despite treatment improvement, the bronchiolitis obliterans syndrome (BOS) affects more than 50% of the lung-transplant recipient in the 5 years post-transplantation and because it cannot…