2017 American Transplant Congress
The Effect of the Procurement Surgeon on Transplanted Abdominal Organ Outcomes: An OPTN/SRTR Analysis to Evaluate Regional Organ Procurement Collaboration.
OBJECTIVE: A number of single center studies have demonstrated utility of regional organ procurement collaboration to reduce travel redundancy by procuring surgical teams with no…2017 American Transplant Congress
B Cells in Liver Transplant Tolerance.
In mice liver transplantation, the liver allografts can be accepted across fully mismatched MHC without immunosuppression. After transplantation, T cells infiltrate into the graft in…2017 American Transplant Congress
Utility of Weighted Composite Endpoints in Kidney Transplantation.
Cleveland Clinic, Cleveland, OH
IntroductionAdvances in therapeutic development and innovation are stifled in transplantation based on difficulties demonstrating efficacy of novel interventions using standard endpoints. Current RCTs are constrained…2017 American Transplant Congress
Identifying the Specific Causes and the Determinants of Outcome in Kidney Recipients with Transplant Glomerulopathy: A Multicenter Study.
BackgroundUnderstanding the specific causes of TG and its long-term consequences at population scale is lacking.MethodsThis study includes all kidney allograft biopsies performed between 2004 and…2017 American Transplant Congress
Center-Level Differences in Outcomes Following High-KDPI Kidney Transplants.
The SRTR reports regularly about center-level differences in graft failure after deceased donor kidney transplantation (DDKT). While these models are adjusted, they provide only information…2017 American Transplant Congress
Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.
Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…2017 American Transplant Congress
Costimulation Independent Acute Rejection Requires CD127 Signaling.
Department of Surgery, Emory University, Atlanta, GA
Clinical costimulation blockade with belatacept leads to improved survival and graft function. However, a subset of patients experience costimulation independent rejection. We identified a critical…2017 American Transplant Congress
Steroid Withdrawal and De Novo Donor-Specific HLA Antibodies in Renal Transplant Patients: A Prospective, Randomized, Controlled Study in Parallel Groups. Preliminary Results.
Introduction: Steroids represent a mainstay of immunosuppression after kidney transplant (KT). Steroid withdrawal reduces metabolic and cardiovascular complications, but whether it increases the risk of…2017 American Transplant Congress
Mycophenolate Dose Reductions Are Not Associated with De Novo Donor-Specific Antibodies.
University of Colorado, Aurora, CO
De novo donor-specific antibodies (dnDSA) are central to the development of antibody-mediated rejection, which is the most important cause of death-censored graft loss. It is…2017 American Transplant Congress
Antioxidant Thermoresponsive Hydrogel as a Versatile Islets Scaffolds for Treating Type I Diabetes.
Introduction: Hepatic islets transplantation procedure to treat type I diabetes often results in limited islets survival presumably due to uneven islet distribution, acute inflammatory response…
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