Am J Transplant, Volume 17, Suppl 3 Archives - Page 175 of 181 - ATC Abstracts

2017 American Transplant Congress
Contemporary Outcomes and Risk Factors of Acute Graft-versus-Host Disease After Liver Transplant.
J. Markus, A. Bukannan, B. Kashat, R. Salgia.
Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI
Introduction:Acute graft-versus-host-disease (GVHD) is a rare complication of orthotopic liver transplant (LT) that has an estimated incidence of 0.1%-2% per year. This complication of OLT…
2017 American Transplant Congress
Epigenetic Modifications in the Progression to Chronic Renal Allograft Injury.
V. Bontha,¹ D. Maluf,¹ M. Dozmorov,² K. Archer,³ L. Gallon,⁴ V. Mas.¹
¹UVA, Charlottesville; ²VCU, Richmond; ³OSU, Columbus; ⁴NWU, Chicago
Background: The renal allograft is exposed to a milieu of environmental/metabolic stimuli that trigger epigenetic modifications and thereby gene expression patterns which influence function and…
2017 American Transplant Congress
Early Results of the UK REVIVE Trial for Ex-Vivo Liver Warm Blood Perfusion of DCD and DBD Livers Using the Portable Organ Care System (OCS™) Liver Technology.
D. Vijayanand, F. Zahreldeen, J. Kingston, S. Farid, T. Mdlongwa, A. Ramsden, S. Willis, C. Moriarty, M. Attia.
Hepatobiliary and Transplant Surgery, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Purpose:TheOCS Liver REVIVE Trial is a single-arm prospective trial to evaluate the safety and performance of OCS™ Liver system to preserve and assess DCD and…
2017 American Transplant Congress
Lower Incidence of DSA-Induced Chronic Antibody-Mediated Rejection in Abo-Incompatible Renal Transplantation.
M. Okada,¹ Y. Watarai,¹ K. Iwasaki,² K. Futamura,¹ T. Hiramitsu,¹ M. Tsujita,¹ N. Goto,¹ S. Narumi,¹ T. Kobayashi.²
¹Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Transplant Surgery, Aichi Medical University, Nagakute, Japan
<INTRODUCTION>Current progress in immunosuppressive therapy has successfully controlled ABO-incompatibility in renal transplantation, although donor specific HLA antibody (DSA) is still insurmountable. Our in vitro experiments…
2017 American Transplant Congress
HLA-DR Based Murine Transplant Model for Studying Collagen Type V Autoimmunity in Chronic Allograft Rejection.
V. Agashe, Y. Zhou, E. Jankowska-Gan, W. Burlingham.
Dept. of Surgery/Transplant Division, UW Madison, Madison, WI
Background: In lung and heart transplant patients, chronic rejection manifests as fibro-obliteration of airways and vessels resulting in bronchiolitis obliterans syndrome (BOS) or cardiac allograft…
2017 American Transplant Congress
Outcomes with Kidney Transplant from Deceased Donors with Acute Kidney Injury and Prolonged Cold Ischemia Time: UNOS Analysis.
G. Dube, S. Mohan, M. Chiles.
Nephrology, Columbia University Medical Center, New York, NY
Longer cold ischemia time (CIT) is associated with an increased risk of delayed graft function and may increase the risk of graft failure. Kidneys with…
2017 American Transplant Congress
Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.
M. So,¹ A. Morris,^1,2 C. Bell,² A. Humar,¹ S. Husain.¹
¹University Health Network, Toronto, ON, Canada; ²Sinai Health System, Toronto, ON, Canada
IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…
2017 American Transplant Congress
In Clinic Systems to Address Adherence Barriers Decrease Late Allograft Rejection for Kidney Transplant Patients.
D. Hooper, C. Varnell, Jr., K. Rich, D. Dahale, J. Huber, A. Pai, A. Modi.
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background: Patient-identified barriers to taking immunosuppressive medications are associated with rejection and allograft loss in kidney transplant patients, yet interventions targeting adherence barriers are rarely…
2017 American Transplant Congress
Time to Kidney Transplantation Following Live Donor Candidate Referral.
K. Kumar, J. Tonascia, A. Muzaale, A. Poon, T. Purnell, J. Garonzik-Wang, E. King, M. Bowring, A. Massie, D. Segev.
Surgery, Johns Hopkins University, Baltimore, MD
Kidney transplant candidates have utilized novel methods to identify and refer willing donors; however, delays or barriers to actually achieving live donor kidney transplantation are…
2017 American Transplant Congress
Anti-CD40 mAb Promotes Kidney Immunoregulatory Capacity in NHP Transplants by Altering Kidney Tubular Cell (TEC) Expression of CD40 and IL-6.
J. Arp,¹ Y. Ma,¹ H. Yang,² A. El Warrak,¹ A. Haig,¹ W. Liu,¹ K. Reimann,³ P. Luke,¹ Z. Zhang,¹ D. Rothstein,⁴ A. Jevnikar.¹
¹Medicine, Pathology & Microbiology & Immunology, Western University, London, ON, Canada; ²Sichuan Provincial Hospital, Chengdu, Sichuan, China; ³University of Massachusetts, Boston, MA; ⁴University of Pittsburgh, Pittsburgh, PA
Treatment of cynolmolgus monkey (NHP) renal transplant recipients with a combination of 2 rhesus-mouse chimeric α-CD45RB (r6G3R1; 6G3) and α-CD40 (r2C10R4; 2C10) mAbs increased circulating…