2017 American Transplant Congress
De Novo DSA Positivity Is Associated with a Higher Rate of Post-Transplant Bacterial and Viral Infections.
Background: BK viremia has been shown to correlate with de novo anti-HLA DSA (dnDSA) in renal transplant patients. However, it is unknown if and how…2017 American Transplant Congress
Prevalence and Clinical Outcomes in Kidney Transplant Patients with Viral and Fungal Opportunistic Infections and Malignancy.
Montefiore Medical Center, Bronx
Opportunistic infections and malignancy after kidney transplant (KTX) are associated with increased morbidity and mortality. We aimed to assess predictors and clinical outcomes in patients…2017 American Transplant Congress
Does Histologic Grade in BK Polyoma Nephropathy Associate with Viral Load, Allograft Dysfunction or Allograft Loss? A Single Center Experience.
1Nephrology, University of Iowa, Iowa City, IA; 2Pathology, University of Iowa, Iowa City, IA
Purpose: BK polyoma nephropathy (BKPyN) is a well-recognized cause of allograft dysfunction and loss after kidney transplant. Despite increased recognition, it is unclear if changes…2017 American Transplant Congress
Predicting Residual Renal Compensation in Living Kidney Donors Post-Donation.
Ohio State University College of Medicine, Columbus, OH
In living kidney donors it is well established that post-donation the remaining kidney undergoes functional hypertrophy; resulting in a 20% – 40% in increase in…2017 American Transplant Congress
α-Lipoc Acid Improve the Short Term Outcomes in Human Liver Transplantation.
In liver transplantation (LT) the postreperfusion syndrome (PRS) is a serious intraoperative complication. The effect of α-lipoic acid (ALA) has not been evaluated. A double…2017 American Transplant Congress
Associations Between Provision of Transplant Pharmacy Services and Center-Level Patient and Graft Outcomes in U.S. Adult Kidney Transplant Programs.
As a follow up to a U.S. transplant pharmacist workforce survey in 2013-14 (AJT 2015;15:2683-90), we assessed associations between transplant pharmacist involvement and daily activities…2017 American Transplant Congress
Reproducibility of the Cobas CMV Test (cobas CMV) and Clinical Concordance with the Cobas Ampliprep / Cobas TaqMan CMV Test (CAP/CTM CMV).
cobas CMV is a new, automated, high-throughput assay for use on the cobas 6800/8800 systems that quantifies CMV DNA in EDTA-plasma. It can be run…2017 American Transplant Congress
Nonmelanoma Skin Cancer Rates Are Not Affected by Chronic HIV(+) or HCV(+) Infection in Organ Transplant Recipients.
Dermatology, Drexel, Philadelphia
Purpose: HIV and HCV are two immune dysregulatory processes that may exacerbate the risk of nonmelanoma skin cancer (NMSC) in organ transplant recipients (OTR), a…2017 American Transplant Congress
Patients with Renal Failure Have a pERK-Dependent Defective TCR-Mediated Activation of CD4+ T Cells.
Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands
Introduction Patients with end-stage renal disease (ESRD) have an impaired immune response with a prematurely aged T cell system. Mitogen-activated protein kinases (MAPKs) including extracellular…2017 American Transplant Congress
Kidney Recipients with 10 Year Belatacept-Treatment Display an Altered T Cell Subset Composition and Low Plasma Cytokine Levels Compared to Matched Patients with CNI-Based Immunosuppression.
Introduction/BackgroundMore than 10 years ago, Belatacept (Bela)-based immunosuppression was investigated in the BENEFIT trial of kidney transplantation (KTx) compared to CNI-based immunosuppression. Bela inhibits T…
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