ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Center-Level Differences in Outcomes Following High-KDPI Kidney Transplants.

    L. Wu, A. Massie, X. Luo, M. Bowring, D. Segev.

    JHU, Baltimore

    The SRTR reports regularly about center-level differences in graft failure after deceased donor kidney transplantation (DDKT). While these models are adjusted, they provide only information…
  • 2017 American Transplant Congress

    Glucocorticoid Receptor – Relaxin Signaling in Liver Transplant Ischemia-Reperfusion Injury (IRI): From Bench-to-Bedside.

    S. Kageyama,1 K. Nakamura,1 R. Sossa,2 E. Reed,2 N. Datta,1 A. Zarrinpar,1 R. Busuttil,1 J. Kupiec-Weglinski.1

    1The Dumont-UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles, CA; 2Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA

    Background: Glucocorticoid receptor (GR) serves as a receptor for relaxin (RLX), a pregnancy hormone, with novel vasoactive and tissue remodeling properties. A phase III clinical…
  • 2017 American Transplant Congress

    Costimulation Independent Acute Rejection Requires CD127 Signaling.

    D. Mathews, Y. Dong, S. Kim, C. Breeden, A. Adams.

    Department of Surgery, Emory University, Atlanta, GA

    Clinical costimulation blockade with belatacept leads to improved survival and graft function. However, a subset of patients experience costimulation independent rejection. We identified a critical…
  • 2017 American Transplant Congress

    Steroid Withdrawal and De Novo Donor-Specific HLA Antibodies in Renal Transplant Patients: A Prospective, Randomized, Controlled Study in Parallel Groups. Preliminary Results.

    J. Alonso-Titos,1 P. Ruiz-Esteban,1 E. Palma,1 V. Lopez,1 A. Caballero,2 M. Leon,3 M. Cobos,4 J. Cruzado,5 J. Sellares,6 A. Torres,4 D. Hernandez.1

    1Nephrology, Regional University Hospital and Malaga University, IBIMA, RD16/0009/0006, Malaga, Spain; 2Immunology, Regional University Hospital, Malaga, Spain; 3Pathology, Regional University Hospital, Malaga, Spain; 4Nephrology, Hospital Universitario de Canarias, CIBICAN, University of La Laguna, RD16/0009/0031, Tenerife, Spain; 5Nephrology, IDIBELL, Hospital de Bellvitge, RD16/0009/0003, Barcelona, Spain; 6Nephrology, Hospital Universitari Vall d'Hebron, RD 16/0009/0030, Barcelona, Spain

    Introduction: Steroids represent a mainstay of immunosuppression after kidney transplant (KT). Steroid withdrawal reduces metabolic and cardiovascular complications, but whether it increases the risk of…
  • 2017 American Transplant Congress

    Mycophenolate Dose Reductions Are Not Associated with De Novo Donor-Specific Antibodies.

    S. Davis, J. Gralla, P. Klem, A. Wiseman, J. Cooper.

    University of Colorado, Aurora, CO

    De novo donor-specific antibodies (dnDSA) are central to the development of antibody-mediated rejection, which is the most important cause of death-censored graft loss. It is…
  • 2017 American Transplant Congress

    Antioxidant Thermoresponsive Hydrogel as a Versatile Islets Scaffolds for Treating Type I Diabetes.

    Y. Zhu,1 X. Zhang,2 G. Ameer,1 X. Luo.2

    1McCormick School of Engineering, Northwestern University, Evanston, IL; 2Feinberg School of Medicine, Northwestern University, Chicago, IL

    Introduction: Hepatic islets transplantation procedure to treat type I diabetes often results in limited islets survival presumably due to uneven islet distribution, acute inflammatory response…
  • 2017 American Transplant Congress

    Successful Launch of an ABO-Incompatible Kidney Transplantation Program to Overcome the Shortage of Compatible Living Donors: Experience at a Single Center.

    S. Song,1 J. Lee,1 J. Lee,1 S.-K. Kwon,1 B. Kim,2,3 J. Lee,1 Y. Kim,1,3 M. Kim,1,3 S. Kim,1,3 K. Huh.1,3

    1Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Nephrology, Yonsei University Health System, Seoul, Republic of Korea; 3The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction:ABO-incompatible (ABOi) kidney transplantation (KT) is being increasingly performed to overcome donor shortages. However, debate persists regarding the post-transplant outcomes of ABOi KT versus that…
  • 2017 American Transplant Congress

    Which Way to Go, Liver Resection or Liver Transplantation for Hepatocellular Carcinoma in Child A Liver Cirrhosis.

    K. Yoon, K.-W. Lee, H. Kim, D. Oh, H.-S. Kim, S. Ahn, S. Hong, N.-J. Yi, K.-S. Suh.

    Department of Surgery, Seoul National University College of Medicine, Seoul, Jongrogu, Republic of Korea

    Introduction: Hepatocellular carcinoma(HCC) has high recurrence rate after liver resection(LR). The recurrence within Milan after LR is only 61- 79% in patient with child A.…
  • 2017 American Transplant Congress

    Program-Specific Offer Acceptance Behavior for Kidney Programs Across the Spectrum of KDPI.

    A. Wey, N. Salkowski, B. Kasiske, A. Israni, J. Snyder.

    Scientific Registry of Transplant Recipients, Minneapolis, MN

    Little is known about the offer acceptance behavior of kidney transplant programs, which affects rates of discard and access to transplant. An offer acceptance model…
  • 2017 American Transplant Congress

    The Use of Kidneys from Deceased Donors Over 80 Years in Kidney Transplantation.

    M. Pérez-Sáez,1 E. Arcos,2 J. Comas,2 J. Pascual.1

    1Nephrology, Hospital del Mar, Barcelona, Spain; 2Organització Catalana de Trasplantaments, Barcelona, Spain

    Patient survival is longer after kidney transplantation (KT) compared with remaining in the waiting list on dialysis. We have questioned if this is true also…
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