Am J Transplant, Volume 17, Suppl 3 Archives - Page 153 of 181 - ATC Abstracts

2017 American Transplant Congress
Assessment and Transplantation of Declined Human Kidneys Using Ex-Vivo Normothermic Kidney Perfusion.
S. Hosgood,¹ M. Hamed,¹ A. Sawpaul,² R. Figueiredo,² K. Saeb-Parsy,¹ C. Wilson,² M. Nicholson.¹
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom; ²Transplantation, Transplant Institute, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom
PurposeThe aim of this study was to make more kidneys available for transplantation by using ex-vivo normothermic kidney perfusion (EVKP) technology to assess the quality…
2017 American Transplant Congress
Patient and Kidney Allograft Survival in Recipients with End Stage Renal Disease from Amyloidosis.
M. Lim,¹ D. Sawinski,¹ J. Cohen,^1,2 B. Weiss,^3,4 J. Hogan,^1,3 L. Dember.^1,3
¹Renal, Electrolyte and Hypertension Division, Hospital of the University of Pennsylvania, Philadelphia, PA; ²Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; ³Penn Amyloidosis Program, Division of Hematology-Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA; ⁴Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA
Background: Data on patient and graft outcomes of kidney transplant recipients with end stage renal disease (ESRD) from systemic amyloidosis is scarce. Methods: We performed…
2017 American Transplant Congress
Stable Deceased Donor Transplantation Rates Among Pediatric Candidates Post-KAS Implementation.
B. Shelton,¹ C. Ray,¹ D. Sawinski,² R. Reed,¹ P. MacLennan,¹ J. Locke.¹
¹University of Alabama at Birmingham, Birmingham; ²University of Pennsylvania, Philadelphia
Background: The Kidney Allocation System (KAS) was implemented in December 2014 and increased access to deceased donor kidney transplant (DDKT) for highly sensitized candidates. Concerns…
2017 American Transplant Congress
Living Kidney Donors: Battling High Attrition Rates During Evaluation Process.
J. Verbesey, A. Bacigalupo, A. Gilbert, A. Li, C. Zuttermeister, M. Grafals, J. Moore, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.
MedStar Georgetown Transplant Institute, Washington DC
With an ever increasing kidney waiting list, a major goal is to expand living donor transplantation (LD). LD increases volume and provides higher quality, longer…
2017 American Transplant Congress
Combination αCD28+αCD40 Costimulation Blockade Attenuates Acute and Chronic Rejection in Non-Human Primates.
N. O'Neill, T. Zhang, W. Sun, G. Braileanu, X. Cheng, I. Tatarov, W. Hassanein, A. Azimzadeh, R. Pierson.
University of Maryland School of Medicine, Baltimore, MD
Purpose: Monotherapy using αCD28 or αCD40 antibodies significantly prolongs graft survival but does not induce tolerance in non-human primates (NHP). Here, we evaluate the relative…
2017 American Transplant Congress
Evolution of Health Related Quality of Life (HRQOL) in Kidney Donors.
H. Ibrahim,¹ D. Berglund,¹ S. Jackson,² A. Matas.¹
¹U of MN, Mpls; ²M Health, Mpls
Most living donors (LDs) enjoy excellent HRQOL after donation. However, most studies addressing HRQOL in this group have ascertained HRQOL related outcomes only at one…
2017 American Transplant Congress
Delayed Renal Implantation Improves Survival Following Simultaneous Liver-Kidney Transplantation in High Acuity Recipients.
K. Lunsford,¹ V. Agopian,² A. Saharia,¹ J. Balough,¹ C. Mobley,¹ S. Gordon-Boroughs,¹ H. Gritsch,² H. Podder,¹ R. Knight,¹ G. Danovitch,² X. Li,¹ A. Gaber,¹ R. Busuttil,² R. Ghobrial.¹
¹Houston Methodist Hospital, Houston, TX; ²David Geffen School of Medicine at UCLA, Los Angeles, CA
OBJECTIVES:Simultaneous liver-kidney transplantation (SLKT) improves survival for liver transplant (LT) recipients with renal dysfunction (RD); however, simultaneous transplant risks KT futility in high acuity recipients.…
2017 American Transplant Congress
Women Are Delisted for Being Too Sick for Liver Transplant More Frequently Than Men.
G. Cullaro, J. Lai.
University of California - San Francisco, San Francisco, CA
Background: Women (W) with cirrhosis awaiting liver transplantation (LT) experience higher rates of waitlist mortality than men (M). We aimed to understand the impact of…
2017 American Transplant Congress
Release of HMGB1 in Serum and Urine of Brain-Death Donors Is Associated with Delayed Graft Function (DGF) of the Kidney.
A. Zmijewska,¹ J. Chen,¹ J. Locke,² J. Zmijewski,¹ R. Mannon.¹
¹Medicine, University of Alabama at Birmingham, Birmingham, AL; ²Surgery, University of Alabama at Birmingham, Birmingham, AL
Delayed kidney graft function (DGF) following a kidney transplant is associated with worse graft survival and higher rejection risk. Risk factors for DGF have been…
2017 American Transplant Congress
Autologous Expanded Tregs and Porcine Hematopoietic Cells to Prolong Xenogeneic Pig Skin Graft Acceptance in Baboons.
J. Stern,¹ S. Kofman,¹ P. Alonso-Guallart,¹ E. Berglund,¹ M. Danton,¹ J. Weiner,¹ D. Ayares,² R. Hawley,¹ K. Yamada,¹ D. Sachs,¹ M. Sykes,¹ A. Griesemer.¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY; ²Revivicor, Blacksburg, VA
Background: Mixed chimerism (MC) has been shown to induce tolerance to allogeneic organs and has shown promise for application to xenotransplants, although long-term tolerance has…