Am J Transplant, Volume 17, Suppl 3 Archives - Page 15 of 181 - ATC Abstracts

2017 American Transplant Congress
Women Are Delisted for Being Too Sick for Liver Transplant More Frequently Than Men.
G. Cullaro, J. Lai.
University of California - San Francisco, San Francisco, CA
Background: Women (W) with cirrhosis awaiting liver transplantation (LT) experience higher rates of waitlist mortality than men (M). We aimed to understand the impact of…
2017 American Transplant Congress
Release of HMGB1 in Serum and Urine of Brain-Death Donors Is Associated with Delayed Graft Function (DGF) of the Kidney.
A. Zmijewska,¹ J. Chen,¹ J. Locke,² J. Zmijewski,¹ R. Mannon.¹
¹Medicine, University of Alabama at Birmingham, Birmingham, AL; ²Surgery, University of Alabama at Birmingham, Birmingham, AL
Delayed kidney graft function (DGF) following a kidney transplant is associated with worse graft survival and higher rejection risk. Risk factors for DGF have been…
2017 American Transplant Congress
Autologous Expanded Tregs and Porcine Hematopoietic Cells to Prolong Xenogeneic Pig Skin Graft Acceptance in Baboons.
J. Stern,¹ S. Kofman,¹ P. Alonso-Guallart,¹ E. Berglund,¹ M. Danton,¹ J. Weiner,¹ D. Ayares,² R. Hawley,¹ K. Yamada,¹ D. Sachs,¹ M. Sykes,¹ A. Griesemer.¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY; ²Revivicor, Blacksburg, VA
Background: Mixed chimerism (MC) has been shown to induce tolerance to allogeneic organs and has shown promise for application to xenotransplants, although long-term tolerance has…
2017 American Transplant Congress
Donor Age Is the Most Important Predictor of Longterm Graft Function in Simultaneous Pancreas-Kidney Transplantation from Donors After Cardiac Death.
J. Chen,¹ D. Mikhail,^1,2 H. Sharma,³ A. Hijazi,¹ D. Nap,¹ L. Stitt,⁴ J. Jevnikar,⁵ M. Cooper,⁶ P. Luke,^1,2 A. Sener.^1,2
¹Schulich School of Medicine and Dentistry, London, Canada; ²Division of Urology, Department of Surgery, Western University, London, London, Canada; ³Division of General Surgery, Department of Urology, Western University, London, Canada; ⁴LW Stitt Statistical Services, London, Canada; ⁵Faculty of Engineering and Architectural Sciences, Ryerson University, Toronto, Canada; ⁶Georgetown University, Washington
STUDY PURPOSE: We analyzed data from UNOS to determine the effects of donor age, donor BMI, and organ cold ischemic time on DCD-SPK graft outcomes.METHODS:…
2017 American Transplant Congress
Analysis of Outcomes in High Risk Kidney Transplants.
E. Liu, M. Aull, J. Lee, S. Kapur.
Kidney and Pancreas Transplantation, NewYork-Presbyterian Weill Cornell Medical Center, New York, NY
Background: The new kidney allocation system implemented in 12/2014 utilizes estimated post-transplant survival scores (EPTS) and kidney donor profile index (KDPI) to optimize recipient survival…
2017 American Transplant Congress
Laparoscopic Sleeve Gastrectomy Improves Renal Transplant Candidacy and Posttransplant Outcomes in Morbidly Obese Patients.
Y. Kim, A. Jung, V. Dhar, J. Tadros, R. Alloway, A. Shields, S. Woodle, T. Diwan.
Surgery, University of Cincinnati, Cincinnati, OH
BACKGROUND: Morbid obesity remains a barrier to kidney transplantation (KT) and is associated with increased delayed graft function (DGF), graft loss, and wound complications. Laparoscopic…
2017 American Transplant Congress
Belatacept Conversion for Calcineurin Inhibitor (CNI) Toxicity: Our First 100 Patients.
R. Crew, S. Patel, A. Pai, I. Batal, H. Fernandez.
Columbia University, New York
Intro: CNIs improve kidney transplant (KT) survival, but have significant toxicities, including graft dysfunction (GD), neurotoxicity (NT), or thrombotic microangiopathy (TMA). Belatacept is an alternative…
2017 American Transplant Congress
Genomic Diversity of Epstein-Barr Virus in Post-Transplant Lymphoproliferative Disorder.
E. Maloney, O. Martinez.
Program in Immunology, Stanford University School of Medicine, Stanford, CA
Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We used next-generation sequencing…
2017 American Transplant Congress
Donor SIRPa Polymorphism Modulates the Innate Immune Response to Allogeneic Grafts.
H. Dai,¹ A. Friday,¹ K. Abou-Daya,¹ A. Williams,¹ M. Oberbarnscheidt,¹ J. Danska,² F. Lakkis.¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ²Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Mice devoid of T, B, NK, and innate lymphoid cells distinguish between self and allogeneic non-self despite the absence of an adaptive immune system. When…
2017 American Transplant Congress
Urinary Proteomic Biomarkers Discovery for Prediction of Acute Rejection in Kidney Transplant Recipients.
H.-Y. Jung, R. Kim, S. Park, J. Park, K. Lee, E. Lee, J.-H. Lim, K. Kim, J.-Y. Choi, J.-H. Cho, S.-H. Park, Y.-L. Kim, C.-D. Kim.
Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea
Background: Early prediction and treatment of acute rejection are crucial in kidney transplant recipients (KTRs) to prevent allograft loss. Changes in the serum and urinary…