ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Prospective DSA Monitoring and Significance of De Novo DSA in Adult Liver Transplantation.

    S. Kubal,1 R. Mangus,1 J. Fridell,1 B. Ekser,1 R. Saxena,2 N. Rush,2 N. Higgins,4 M. Ghabril,3 M. Lacerda,3 A. Lobashevsky.4

    1Department of Surgery, Division of Transplantation, Indiana University School of Medicine, Indianapolis, IN; 2Department of Pathology, Indiana University School of Medicine, Indianapolis, IN; 3Department of Gastroenterology, Division of Hepatology, Indiana University School of Medicine, Indianapolis, IN; 4Department of Medicine, Immunology/Histocompatibility Laboratory, Indiana University School of Medicine, Indianapolis, IN

    Background: Post transplant course of circulating de novo donor specific antibodies (DSA) remains unknown after liver transplantation (LT).Methods: In a prospective study, sera from 92…
  • 2017 American Transplant Congress

    Steroid-Free Immunosuppression After Liver Transplant for Autoimmune Disease Does Not Result in Increased Disease Recurrence.

    A. Hooper,1 C. Frenette.2

    1Internal Medicine, Scripps Mercy Hospital, San Diego, CA; 2Organ Transplant, Scripps Green Hospital, La Jolla, CA

    Immunosuppression regimens in patients with end stage liver disease (ESLD) from autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) typically include…
  • 2017 American Transplant Congress

    Sensitized KPD Pairs Take Longer to Find Matches.

    C. Holscher,1 E. Chow,1 C. Purcell,2 M. Ronin,2 J. Garonzik-Wang,1 A. Massie,1 S. Gentry,3 D. Segev.1

    1Johns Hopkins University, Baltimore; 2National Kidney Registry, New York; 3US Naval Academy, Annapolis

    Kidney paired donation (KPD) can facilitate living donor transplantation for candidates with an incompatible donor, but it is unclear how sensitization or blood type affects…
  • 2017 American Transplant Congress

    African American Living Kidney Donors' Attitudes About APOL1 Genetic Testing: Implications for Evaluation and Informed Consent.

    E. Gordon,1 C. Johnson,1 C. Wicklund,1 R. Sharp,2 J. Friedewald.1

    1Northwestern University, Chicago, IL; 2Mayo Clinic, Rochester

    BackgroundAfrican American (AA) live kidney donors (LKDs) have a greater risk than European American live donors of kidney failure. Apolipoprotein 1 (APOL1) gene variants in…
  • 2017 American Transplant Congress

    Effect of AKI Donor Admit Creatinine on Renal Transplant Outcomes.

    E. Giorgakis,1 R. Heilman,2 H. Khamash,2 B. Kaplan,2 A. Moss,1 M. Smith,3 K. Reddy.1

    1Department of Surgery, Mayo Clinic, Phoenix, AZ; 2Department of Medicine, Mayo Clinic, Phoenix, AZ; 3Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ

    Purpose of the study was to explore the effect of admit AKI donor creatinine on graft outcomes.Method: Single center retrospective analysis of kidney transplants performed…
  • 2017 American Transplant Congress

    Screening and Referral of High Risk Liver Transplant Recipients to a Transitional Care Coordination (TCC) Program to Reduce Hospital Readmissions.

    A. Masoumi,1 J. Krzyzewski,1 T. Stern,1 N. Schluterman,2 D. Bruno,2 J. Bromberg,2 R. Barth,2 S. Hanish.2

    1University of Maryland Medical Center, Baltimore, MD; 2University of Maryland School of Medicine, Baltimore, MD

    Introduction One-fifth of Medicare patients are readmitted to the hospital. The readmission rate among liver transplant recipients at a large tertiary academic medical center in…
  • 2017 American Transplant Congress

    Pre-Kidney Transplant Lower Extremity Impairment and Post-Transplant Mortality.

    A. Nastasi,1,2 M. McAdams-DeMarco,1,2 J. Schrack,1 H. Ying,2 C. Haugen,2 M. González Fernández,3 D. Segev.1,2

    1Epidemiology, Johns Hopkins University, Baltimore, MD; 2Surgery, Johns Hopkins University, Baltimore, MD; 3Physical Medicine and Rehabilitation, Johns Hopkins University, Baltimore, MD

    INTRODUCTION. Few objective tests can be easily performed prior to kidney transplantation (KT) to effectively stratify patients by risk of post-KT mortality. The short physical…
  • 2017 American Transplant Congress

    EXPANDER-1: Exploring Renal Transplants Using Hepatitis-C Infected Donors for HCV-Negative Recipients.

    C. Durand, D. Brown, R. Wesson, N. Bhair, F. Naqvi, D. Ostrander, M. Bowring, A. Massie, S. Rasmussen, J. Sugarman, D. Segev, M. Sulkowski, N. Desai.

    JHU, Baltimore, MD

    Kidneys from hepatitis C-infected (HCV+) donors are underutilized in an era of severe organ shortage. In an effort to expand the donor pool, we evaluated…
  • 2017 American Transplant Congress

    TACI Polymorphisms Associated with De Novo Alloantibodies in Humans and Allograft Rejection in Mice.

    J. Platt,1 E. Farkash,2 A. Lefferts,1 M. Samaniego,3 M. Cascalho.1

    1Surgery, University of Michigan, Ann Arbor, MI; 2Pathology, University of Michigan, Ann Arbor, MI; 3Internal Medicine, University of Michigan, Ann Arbor, MI

    A. Trans-membrane Activator and CAML Interactor (TACI) controls B cell differentiation and memory and exists as numerous allelic variants among healthy individuals and individuals with…
  • 2017 American Transplant Congress

    Minimal Effect of Broader Heart Sharing on Regional Outcomes.

    A. Bitar,1 M. Skeans,2 R. Davies,3 M. Farr,4 A. Kao,5 L. Robbins-Callahan,6 J. Rogers,7 S. Silvestry,8 M. Colvin.1,2

    1U of MI, Ann Arbor, MI; 2SRTR, Mpls, MN; 3Nemours/AIDHC, Wilmington, DE; 4Columbia U, NY, NY; 5Mid-America Heart Inst, KC, MO; 6UNOS, Richmond, VA; 7Duke U, Durham, NC; 8FL Hosp Transplant Inst, Orlando, FL

    The OPTN/UNOS Heart Subcommittee proposed a revision to policy 6 (Allocation of Hearts and Heart-Lungs) to better address heart transplant candidate medical urgency. They developed…
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