Porta Systemic Shunts Helps Us to Delay or Avoid Liver Transplantation in Patients with Portal Hypertension Post Kasai Operation for Biliary Atresia.
Paediatric Surgery and Transplant Surgery, Children's Hospital at Westmead, Sydney, NSW, Australia
Meeting: 2017 American Transplant Congress
Abstract number: B282
Keywords: Biliary atresia, Hypertension, Liver cirrhosis, Portal veins
Session Information
Date: Sunday, April 30, 2017
Session Name: Poster Session B: Pediatric Liver Transplant - Clinical
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
We present a series of 10 patients who had Kasai operation for biliary atresia in the neonatal period. These patients had optimally functioning liver in the follow up period. However they were complicated by portal hypertension and gastro intestinal bleeding. This was managed by a porta systemic shunt. Our follow up showed that except for one none of the others required liver transplant. One patient ended having a transplant due to shunt failure, ongoing cirrhosis and deterioration of portal hypertension.
Native liver is the best for paediatric patients ,avoiding the hazards of immunosuppression in a transplanted liver. Biliary atresia is a challenging condition in that the success varies between 30 to 70 % . If there is an optimally functioning liver but complicated by portal hypertension(PHTN) our approach was to treat the PHTN by a portal systemic shunt rather than a liver transplant. We could avoid liver transplant in all except one. Follow up showed good liver function and abatement of PHTN and GI bleeding.
CITATION INFORMATION: George M, Thomas G, Shun A. Porta Systemic Shunts Helps Us to Delay or Avoid Liver Transplantation in Patients with Portal Hypertension Post Kasai Operation for Biliary Atresia. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
George M, Thomas G, Shun A. Porta Systemic Shunts Helps Us to Delay or Avoid Liver Transplantation in Patients with Portal Hypertension Post Kasai Operation for Biliary Atresia. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/porta-systemic-shunts-helps-us-to-delay-or-avoid-liver-transplantation-in-patients-with-portal-hypertension-post-kasai-operation-for-biliary-atresia/. Accessed June 6, 2020.« Back to 2017 American Transplant Congress