ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Expression of T-Cell Mediated Rejection (TCMR) Associated Genes in Native and Renal Allograft Renal Biopsies with Inflamed Scars (i-IFTA).

    Z. Lyu,1 L. Pang,1 G. Zeng,2 Y. Huang,2 P. Randhawa.2

    1Pathology & Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; 2Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    The presence of i-IFTA in allograft kidney biopsies is a bad prognostic parameter. However, despite the presence of T-cell infiltrates in these lesions there is…
  • 2017 American Transplant Congress

    Ex-Situ Extended Limb Preservation: A Protocol for Porcine Limb Perfusion.

    E. Dalla Pozza,1 E. Duraes,1 M. Madajka,1 R. Frautschi,1 K. Cho,1 N. Dawlagala,1 V. Fahradyan,1 H. Shah,1 C. Cakmakoglu,1 C. Quintini,2 F. Papay,1 A. Rampazzo,1 B. Bassiri Gharb.1

    1Plastic Surgery, Cleveland Clinic, Cleveland, OH; 2General Surgery, Cleveland Clinic, Cleveland, OH

    Background: Ischemia and reperfusion injury remains a significant limiting factor for the success of vascularized composite allotransplantation. Compared to the cold storage of the procured…
  • 2017 American Transplant Congress

    Meta-Analysis of Clinical Significance of Complement Activating Anti-HLA DSA in Kidney Transplantation.

    A. Bouquegneau,1,2 C. Ulloa,1 O. Aubert,1 C. Loheac,1 D. Viglietti,1 J. Empana,1 P. Jabre,1 X. Jouven,1 C. Lefaucheur,1 A. Loupy.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2Department of Nephrology, Dialysis and Transplantation, Liège, Belgium

    Donor-specific anti-HLA antibodies (DSA) are currently recognized as the major limitation to access transplantation and the first cause of late transplant failures. The effect of…
  • 2017 American Transplant Congress

    Podocyte-Specific Knockdown of SHROOM3 Causes Albuminuria and Foot-Process Effacement by Interaction with FYN.

    M. Menon, N. Philippe, C. Wei, W. Zhang, J. He, B. Murphy.

    Nephrology, Medicine, Icahn School of Medicine, New York, NY

    In the translational GoCAR study, we identified that a CKD-associated SHROOM3-SNP, and tubular SHROOM3 expression correlated with the development of renal fibrosis post-transplant. The SNP…
  • 2017 American Transplant Congress

    Single Kidney Transplantation from DCD Maastricht Category 3 Donors ≥ 60 Years: Is It Safe?

    E. Favi,1 C. Puliatti,2 M. Ferraresso,1 S. Iesari,3 R. Cacciola.2

    1Renal Transplant, Ospedale Maggiore Policlinico, Milan, Italy; 2Renal Transplantation, The Royal London Hospital, London, United Kingdom; 3Organ Transplant, Presidio Ospedaliero S. Salvatore, L'Aquila, Italy

    Aim. Compared to DBD, DCD kidneys show higher rates of primary non function (PNF), DGF, rejection, and premature transplant (Tx) loss. Some authors have advised…
  • 2017 American Transplant Congress

    Performance-Based vs. Self-Reported Functional Assessment on Outcomes After Kidney Transplant.

    K. Tibaldi, N. Dhillon, R. Goldberg, H. Paniagua, A. Patel.

    Renal and Pancreas Transplant Department, Saint Barnabas Medical Center, Livingston, NJ

    Reduced functional capacity (FC) is associated with poor outcomes and early hospital readmission after kidney transplant (KT). The aim of the study was to determine…
  • 2017 American Transplant Congress

    A Dedicated Young Adult Service with a Youth Worker Increases Engagement of Teenagers and Young Adults with Kidney Transplantation and Impacts Favourably on Clinical Outcomes.

    D. Cross, P. Harden.

    Oxford Transplant Centre, Oxford University Hospital NHS Foundation Trust, Oxford, United Kingdom

    Transition from pediatric to adult care is associated with a high risk of transplant loss, increased morbidity and mortality. Frequently there is poor engagement by…
  • 2017 American Transplant Congress

    Living Kidney Donor Pharmaceutical Care Needs Identified Through Linked Transplant Registry and Pharmacy Claims Data.

    K. Lentine,1 S. Gustafson,2 M. Schnitzler,1 G. Hess,3 D. Segev,4 A. Garg,5 N. Lam,6 D. Axelrod,7 D. Brennan,8 H. Randall,1 B. Kasiske.9

    1St Louis Univ, St Louis, MO; 2SRTR, Minneapolis, MN; 3Symphony Health, Philadelphia, PA; 4Johns Hopkins, Baltimore, MD; 5Western Univ, London, Canada; 6Univ Alberta, Edmonton, AB, Canada; 7E Carolina Univ, Greenville, NC; 8Washington Univ, St. Louis, MO

    Limited data are available on pharmaceutical care needs of living kidney donors (LKD).We integrated 1) national US Scientific Registry of Transplant Recipients data for LKD…
  • 2017 American Transplant Congress

    Prominence of Graft-Infiltrating PD-L1hi Cross-Dressed Dendritic Cells in Mouse Liver Transplant Tolerance.

    Y. Ono, A. Perez Gutierrez, S. Yokota, O. Yoshida, T. Nakao, G. Camirand, D. Geller, A. Thomson.

    Surgery, University of Pittsburgh, Pittsburgh, PA

    Background: The mechanism underlying spontaneous liver allograft tolerance remains unclear. Given recent reports on the key role of recipient mouse dendritic cells (DCs) in host…
  • 2017 American Transplant Congress

    Temporal Trends and Variation in BMI Thresholds for Living Donation Across the US.

    A. Naik,1 D. Cibrik,1 A. Sakhuja,2 K. Lentine.3

    1U Michigan, Ann Arbor; 2Mayo Clinic, Rochester; 3St. Louis U, St Louis

    The acceptable BMI threshold for living kidney donation is controversial. We examined the variability in center acceptance of living donors with high Body Mass Index…
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