Am J Transplant, Volume 16, Suppl 3 Archives - Page 78 of 180 - ATC Abstracts

2016 American Transplant Congress
Surgical Techniques in Modified Multiorgan Transplantation.
W. Ju, J. Lin, J. Zhou, M. Chen, A. Yang, D. Wang, Y. Ma, Z. Guo, M. Han, X. Wang, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Objective: Investigate the clinical efficacy of combined en-bloc liver-pancreas transplantation in patients with end stage liver disease and diabetes.Method: The clinical data of 19 cases…
2016 American Transplant Congress
Profiling of T Cell Subsets in a Primate Cardiac Transplant Model.
N. O'Neill, T. Zhang, G. Braileanu, W. Sun, X. Cheng, C. Evans, R. Pierson, A. Azimzadeh.
Surgery, University of Maryland, Baltimore, MD.
Purpose: Costimulation blockade prolongs graft survival but does not induce tolerance in primates, and mechanisms of rejection are incompletely understood. Here we evaluate changes in…
2016 American Transplant Congress
Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2).
E. Yin,^1,2 M. Uchiyama,^1,3 X. Jin,^1,4 T. Shimokawa,³ H. Yagita,⁵ M. Niimi.¹
¹Surgery, Teikyo University, Tokyo, Japan; ²Cardiovascular Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China; ³Cardiovascular Surgery, Teikyo University, Tokyo, Japan; ⁴Thoracic Surgery, The 3rd Affiliated Hospital of Harbin Medical University, Harbin, China; ⁵Immunology, Juntendo University Hospital, Tokyo, Japan.
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…
2016 American Transplant Congress
Porcine Islets Engineered with SA-FasL Protein Induces Robust Tolerance in Mice through CD4⁺CD25⁺FoxP3⁺ Treg Cells.
K. Woodward,¹ H. Zhao,¹ H. Shirwan,¹ F. Wang,¹ M. Graham,² B. Hering,² E. Yolcu.¹
¹Institute for Cellular Therapeutics and Department of Microbiology and Immunology, University of Louisville, Louisville, KY; ²Schulze Diabetes Institute and Department of Surgery, University of Minnesota, Minneapolis, MN.
Introduction: We have shown that porcine islets engineered to transiently display SA-FasL protein on their surface establish tolerance in mice following transplantation under the kidney…
2016 American Transplant Congress
The Impact of Non-Adherence on Disparities in African-American Kidney Transplant Recipients.
D. Taber, A. Chokkalingam, A. Posadas, R. Browning, N. Salazar, M. Kamel, R. Pullalarevu, B. Kadri, T. Srinivas, K. Chavin, P. Baliga.
MUSC, Charleston, SC.
Background: Non-adherence is considered to a be a strong risk factor for graft loss in kidney transplant recipients, with conflicting evidence of its impact on…
2016 American Transplant Congress
Predicting Survival to Listing for Liver Transplantation: Do MELD and Race Interact?
M. Jesse, E. Goldstein, N. Rebhan, C.-X. Ho, T. Macaulay, M. Bebanic, L. Shkokani, D. Moonka, M. Abouljoud, A. Yoshida.
Transplant Institute, Henry Ford Health System, Detroit.
Minimal research has been focused on the evaluation process for liver transplant listing. The purpose of this study was to examine whether evaluation MELD score…
2016 American Transplant Congress
Effect of Modifying Life Support Withdrawal Practices on Outcomes of Donation After Circulatory Death in Liver Transplantation: A Meta-Analysis.
Y. Cao,^1,2 S. Shahrestani,³ H. Chew,^2,4 M. Crawford,⁵ P. Macdonald,^1,2,4 J. Laurence,^3,5,7 W. Hawthorne,^3,6 K. Dhital,^1,2,4 H. Pleass.^3,5,6
¹Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia; ²Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; ³Sydney Medical School, University of Sydney, Sydney, NSW, Australia; ⁴Cardiac Transplant Unit, St. Vincent's Hospital, Sydney, NSW, Australia; ⁵Australian National Liver Transplant Unit, Royal Prince Alfred Hospital, Sydney, NSW, Australia; ⁶The Department of Surgery, Westmead Hospital, Sydney, NSW, Australia; ⁷Institute of Academic Surgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Aim. Donor warm ischaemic time is identified as the main risk factor for poor outcomes in liver transplantation using donation after circulatory death (DCD) compared…
2016 American Transplant Congress
Quadruple Induction Regimen with Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Improves Graft Function without Increase in the Incidence of Microvascular Inflammation or De Novo Donor Specific Antibody Compared to the Standard Triple Regimen.
M. Miura, H. Higashiyama.
Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Nephrotoxicity of calcineurin inhibitors (CNI) in kidney allografts has been a significant problem even with low exposure regimens. On the other hand, CNI-free regimen…
2016 American Transplant Congress
Everolimus and Low Dose Cyclosporine Immunosuppressive Regimen and Development of Anti HLA Donor Specific Antibodies.
E. Minetti,¹ L. Di Maria,¹ L. Caroti,¹ E. Buti,² P. Carta.¹
¹Nephrology unit, Careggi University Hospital, Florence, Italy; ²Nephrology Unit, Mayer Univerity Hospital, Florence, Italy.
Few data are available on the rate of de novo anti-HLA donor specific antibodies (DSA) with the use of everolimus in kidney transplant recipients.MaterialsWe selected…
2016 American Transplant Congress
The Impact of Donor Origin on Survival after Orthotopic Heart Transplantation.
O. Kiamanesh, A. Khosla, C. Imai, E. Johansson, S. Virani, M. Davis, A. Cheung, J. Bashir, B. Munt, A. Ignaszewski, A. Kaan, M. Toma.
University of British Columbia, Vancouver, BC, Canada.
BackgroundOrthotopic heart transplantation (OHT) is the gold standard for the management of select patients with end-stage heart failure, but limited by an ongoing organ donor…