2016 American Transplant Congress
Heterologous Persistent and Latent Viral Infections Do Not Impact Graft Survival.
1Duke University, Durham; 2Emory University, Atlanta.
Purpose: Infection induces costimulation-resistant memory T cells with heterologous alloreactivity. Rapamycin has been shown to mitigate the effect of these cells in transplant rejection. Previous…2016 American Transplant Congress
Neonatal Tolerance to Blood Group A-Antigen in a Mouse Model of ABO-Incompatible Heart Transplantation (ABOi HTx).
Purpose: ABOi HTx can be performed safely in infants due to lack of natural anti-A/B antibodies (Ab), in contrast to adults. Following ABOi HTx, B…2016 American Transplant Congress
A Novel Humanized Mouse Model Incorporating Non-Fetal Tissue.
Surgery/Transplant Division, University of Wisconsin-Madison, Madison, WI.
Pre-clinical research into allogeneic tissue transplantation therapies, as well as patient-specific regenerative medicine studies, require animal models that closely mimic the typical patient's immune response.…2016 American Transplant Congress
Attitudes Toward Living Kidney Transplantation Among Potential Transplant Candidates.
1Yale U, New Haven; 2U Pennsylvania, Philadelphia; 3Northwestern U, Chicago.
Background: Prior studies have shown that transplant candidates who are minorities and less educated are less willing to talk to others about living kidney donor…2016 American Transplant Congress
Psychiatric Characteristics of Acute Liver Failure Patients: Acetaminophen Overdose versus Other Etiologies.
Transplant Institute, Henry Ford Health System, Detroit.
Scant research exists on the psychiatric history of patients with acute liver failure (ALF) presenting for liver transplantation. This study compared psychiatric profiles of patients…2016 American Transplant Congress
Impact of the National Overdose Death Epidemic on the Deceased-Donor Pool.
Beginning in 2010, there was a dramatic increase in heroin and other opioid overdose(OD) deaths in several regions across the country, primarily among young Caucasians.…2016 American Transplant Congress
Impact on Wound Healing Events After Early Conversion to Everolimus in De Novo Renal Transplant Recipients: 24-Month Results from the Randomized ELEVATE Study.
BackgroundWound healing events (WHE) are probably the most common type of post-transplant (Tx) surgical complication. Due to its antiproliferative properties, mammalian target of rapamycin inhibitors…2016 American Transplant Congress
A Weighted Approach to Composite Efficacy Analysis in Kidney Transplantation.
The US92 study determined whether, in de novo renal transplant patients, concentration-controlled everolimus (EVR) with reduced dose tacrolimus (RTAC) is non-inferior to CellCept® (mycophenolate mofetil…2016 American Transplant Congress
Predictors of Donor Heart Utilization in United States.
Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY.
BackgroundOptimum use of donor organs can increase the reach of the transplant therapy to more patients on waitlist. The heart transplant (HTx) has remained stagnant…2016 American Transplant Congress
Anti-HLA Antibody Composition and Outcomes in Pediatric Heart Transplant Recipients with a Positive Cross-Match.
Purpose: Utilization of positive (+) cross-match (XM) hearts is tempting when shortages of pediatric donor hearts exist, especially for patients with high pre-transplant panel reactive…
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