Am J Transplant, Volume 16, Suppl 3 Archives - Page 60 of 180 - ATC Abstracts

2016 American Transplant Congress
Combination of Delayed Kidney Transplant (KT) and Better Quality Kidneys Offers Excellent Patient Survival in Combined Liver-Kidney Transplantation (CLKT).
B. Ekser, R. Mangus, J. Fridell, C. Kubal, D. Bayt, S. Nagaraju, P. Mihaylov, J. Powelson, W. Goggins, A. Tector.
Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN.
Background: Despite prioritizing high MELD patients with the share-35 policy, patient survival in CLKT is relatively low. We previously showed the positive impact of delayed…
2016 American Transplant Congress
Intervention Development for the Allocation System Changes for Equity in kidNey Transplantation (ASCENT) Study.
K. Smith,¹ J. Gander,¹ M. Basu,¹ S. Pastan,¹ S. Mohan,² C. Escoffery,¹ L. Plantinga,¹ S. Kalloo,² G. Green,³ A. Berlin,⁴ G. Renville,⁵ T. Browne,⁶ N. Turgeon,¹ S. Caponi,⁷ J. Krisher,⁸ R. Patzer.¹
¹Emory University, Atlanta, GA; ²Columbia University, New York, NY; ³American Association of Kidney Patients, Tampa, FL; ⁴Southeastern Kidney Transplant Coalition, Atlanta, GA; ⁵National Kidney Foundation, Atlanta, GA; ⁶University of South Carolina, Columbia, SC; ⁷ESRD Network 2, Lake Success, NY; ⁸ESRD Network 6, Raleigh, NC.
Background: Recent changes in the kidney allocation system (KAS) are expected to reduce racial disparities in kidney transplantation (KTx). However, dialysis facilities may not be…
2016 American Transplant Congress
“Day 2 Discharge” After Kidney Transplantation: Complications, Health Care Utilization, and Long-Term Clinical Outcomes.
A. Mathur, N. Katariya, A. Welu, J. Chang, R. Heilman, A. Singer, H. Khamash, H. Chakkera, W. Hewitt, D. Haakinson, M. Maningo-Salinas, E. Oakley, A. Moss, K. Reddy.
Transplant Center, Mayo Clinic, Phoenix.
Background: Reducing kidney transplant length of stay is a priority for many stakeholders. We aimed to determine whether very early discharge – on or before…
2016 American Transplant Congress
Influence of Lipid Levels on Cardiovascular Events After Early Conversion from Calcineurin Inhibitor to Everolimus: 24 M Analysis of the ELEVATE Study.
M. van der Giet,¹ J. de Fijter,¹ F. Oppenheimer,¹ L. Toselli,¹ G. Russ,¹ P. Lopez,² J. Aguilar,² P. Bernhardt,² Z. Wang,³ J. Cruzado,¹ H. Holdaas.¹
¹ELEVATE study group, Berlin, Germany; ²Novartis pharma AG, Basel, Switzerland; ³Novartis Pharmaceutical Corporation, East Hanover, NJ.
Background: Immunosuppressive therapies are probably the most important cause of hyperlipidemia post-renal transplantation (RTx). Lipid abnormalities represent important biomarkers for cardiovascular (CV) risk. Here, we…
2016 American Transplant Congress
A Prospective Carfilzomib-Based Desensitization Trial: Phase 1 Results.
S. Tremblay,¹ A. Shields,¹ R. Alloway,¹ P. Brailey,¹ B. Abu Jawdeh,¹ T. Latif,¹ J. Driscoll,¹ M. Pando,² A. Girnita,¹ E. Woodle.¹
¹U Of Cincinnati, Cincinnati; ²Mayo Clinic, Phoenix.
Carfilzomib (CFZ) is mechanistically distinct from bortezomib as it is an irreversible PI. Results from phase 1 of a CFZ desensitization (DS) trial are presentedMethods:…
2016 American Transplant Congress
Liver-Intestine Candidates Benefit from National Sharing.
E. Edwards,¹ A. Harper, D. Sudan.
¹United Network for Organ Sharing, Richmond, VA; ²Duke University Hospital, Durham, NC.
Introduction. On June 18, 2013, the OPTN implemented regional sharing of adult donor livers for candidates with allocation MELD/PELD scores of 35 and greater. As…
2016 American Transplant Congress
Role of Regulatory T Cells in Induction of Tolerance in Mouse Vascularized Osteomyocutaneous Allotransplantation Under Combined Costimulation Blockade.
M. Anggelia,¹ H.-Y. Cheng,¹ Y.-L. Wang,¹ W.-Y. Chuang,¹ C.-H. Lin,¹ G. Brandacher,² F.-C. Wei,¹ C.-H. Lin.¹
¹Center for Vascularized Composite Allotransplantation, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; ²Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA) Laboratory, Johns Hopkins University School of Medicine, Baltimore, MD.
Background: The role of regulatory T cells (Tregs) in allograft tolerance has been studied using various transplant models, but the mechanism in vascularized composite allotransplantation…
2016 American Transplant Congress
Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.
C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.
CVID and IGS, University of Maryland School of Medicine, Baltimore, MD.
Hypothesis: We previously presented highly significant differences in the bacterial community structures of human renal allograft recipients over time. Likewise, murine normal, colitic, and pregnant…
2016 American Transplant Congress
Ameliorating Progression of Allograft Vasculopathy by Targeting the T Follicular Helper Cell Subset.
M. Chhabra, J. Ali, J. Alsughayyir, S. Qureshi, J. Bradley, E. Bolton, R. Motallebzadeh, G. Pettigrew.
Department of Surgery, University of Cambridge, Cambridge, United Kingdom.
BACKGROUNDDevelopment of long-lived alloantibody is closely linked with chronic rejection and graft failure. We examined in a murine model of antibody-mediated rejection (AMR) if targeting…
2016 American Transplant Congress
The Survival Benefit of Pancreas and/or Kidney Transplantation for Patients with Type 1 Diabetes.
R. Gruessner, V. Whittaker, N. Ozden, A. Gruessner.
SUNY Upstate Medical University, Syracuse, NY.
Introduction: Deceased donor transplantation (tx) has provided an enormous survival benefit for patients with end-stage organ failure. An analysis of the survival benefit for type…