ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Hospital Readmissions Following Incompatible Kidney Transplantation: A Multi-Center Study.

    B. Orandi, E. King, X. Luo, S. Bae, B. Lonze, R. Montgomery, D. Segev.

    Johns Hopkins, Baltimore.

    Desensitization and incompatible live donor kidney transplantation (ILDKT) has improved survival vs. forgoing transplant or waiting for a compatible one. It is unknown if increased…
  • 2016 American Transplant Congress

    NEAD Chains Do Not Disadvantage Blood Type O, Black, or Highly Sensitized Patients.

    M. Rees,1 J. Roberts,2 K. Lentine,3 A. Roth,4 A. Leichtman,5 H. Xiao,3 S. Rafizadeh,1 E. Neidich,2 M. Melcher.4

    1UT, Toledo; 2UCSF, SF; 3SLU, St Louis; 4Stanford, Palo Alto; 5Arbor Res, Ann Arbor.

    Introduction: NEAD chains raised concern that wait-listed blood type (BT) O patients and racial minorities would be disadvantaged by allocation of a non-directed donor (NDD)…
  • 2016 American Transplant Congress

    Reduced Incidence of Rejection in AB0-incompatible Kidney Transplantation – Five Year Follow-Up in a Single Center.

    A. Weidemann, F. Karpf, T. Dienemann, K. Birkner, J. Jacobi, K.-U. Eckardt.

    Nephrology and Hypertension, Universitaet Erlangen-Nuernberg, Erlangen, Germany.

    Introduction:Living kidney donation is the method of choice to expand the donor pool in times of severe organ shortage. In many centers, AB0-incompatible kidney transplantation…
  • 2016 American Transplant Congress

    Biopsies for Delayed Graft Function After Alemtuzumab Induction in Kidney Transplantation: The Incidence of Early Rejection After Alemtuzumab Is Very Low but Not Negligible.

    E. McGuire, C. Roufosse, T. Cook, D. Ashby, T. Cairns, J. Galliford, M. Willicombe, D. Taube, A. McLean.

    Imperial Kidney & Transplant Centre, Hammersmith Hospital, Imperial College Healthcare, London, United Kingdom.

    IntroductionUK practice advocates transplant biopsy (Bx) at day 7, then weekly in the presence of delayed graft function (DGF) because if missed, early rejection adversely…
  • 2016 American Transplant Congress

    The Impact of Allograft Rejection on DNA Methylation After Kidney Transplantation.

    K. Boer, E. de Wit, D. Hesselink, L. Hofland, M. Betjes, C. Baan.

    ErasmusMC, University Medical Center Rotterdam, Rotterdam, Netherlands.

    Introduction DNA methylation is a well-known epigenetic mechanism which plays a critical role in cell function by regulating gene expression. Variations in DNA methylation are…
  • 2016 American Transplant Congress

    Intraoperative Blood Loss Is a Promoter of Early Tumor Recurrence in Liver Transplant Patients with High Risk Hepatocellular Carcinoma.

    A. Kornberg,1 U. Witt,1 J. Kornberg,2 H. Friess,1 K. Müller,3 K. Thrum.4

    1Surgery, Technical University, Munich, Germany; 2Anesthesiology, Ludwig-Maximilians-University, Munich, Germany; 3FSU, Jena, Germany; 4Pathology, Helios-Klinikum, Berlin, Germany.

    Background:Currently, there is an increasing body of evidence that risk of early hepatocellular carcinoma (HCC) relapse following liver transplantation (LT) may be promoted by mechanisms…
  • 2016 American Transplant Congress

    Pretransplant Serum Hyaluronic Acid Can Be a Prognostic Predictor in Adult-to-Adult Living Donor Liver Transplantation.

    S. Mizuno,1 B. Das,2 Y. Iizawa,1 H. Kato,1 Y. Murata,1 A. Tanemura,1 N. Kriyama,1 Y. Azumi,1 M. Kishiwada,1 M. Usui,1 H. Sakurai,1 S. Isaji.1

    1Hepatobiliary-Pancreatic and Transplant Surgery, Mie University, Tsu, Japan; 2Hepatobiliary Pancreatic Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

    Objectives:Recently, hyaluronic acid (HA) levels of the solution during graft preservation has been reported to be associated with primary non function in deceased donor liver…
  • 2016 American Transplant Congress

    A Multi-Center Study of Factors That Increase Cognitive Load in Living Donor Liver Transplants.

    A. Lee,1 R. Khorzad,1 E. Pomfret,2 J. Guarrera,3 R. Fisher,4 M. Simpson,2 A. Skaro,1 A. Daud,1 N. Salehitezangi,1 D. Woods,1 D. Ladner.1

    1Northwestern University, Chicago, IL; 2Lahey Clinic, Burlington, MA; 3Columbia University, New York, NY; 4Virginia Commonwealth Univeristy, Richmond, VA.

    Background: Studies have shown that distractions in the operating room (such as phones/pagers, irrelevant conversations, ins and outs) can negatively affect concentration and performance, and…
  • 2016 American Transplant Congress

    A 30% Decrease in Post-kidney Transplant Estimated Glomerular Filtration Rate (eGFR) from 6 Mo-2 Y Is a Surrogate for 5 Y eGFR: Results from Clinical Trials in Organ Transplantation-(CTOT)-17.

    G. Faddoul,1 G. Nadkarni,1 D. Hricik,2 P. Heeger,1 CTOT17 Investigators.

    1Medicine and Recanati Miller Transplant Institute, Icahn School of Medicine, NY, NY; 2Medicine, Case Medical Center, Cleveland, OH.

    Predicting long-term kidney allograft outcomes using early clinical/biomarker data could guide individualized therapy. Emerging evidence in progressive native kidney disease indicates >30% decrease in eGFR…
  • 2016 American Transplant Congress

    The Effect of Spironolactone on Calcineurininhibitor Induced Nephrotoxicity.

    L. Mortensen,1 H. Thiesson,1 C. Bistrup,1 F. Nielsen,3 U. Halekoh,2 B. Jensen,3 N. Marcussen.4

    1Department of Nephrology, Odense University Hospital, Odense, Denmark; 2Department of Biostatistics, University of Southern Denmark, Odense, Denmark; 3Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; 4Department of Clinical Pathology, Odense University Hospital, Odense, Denmark.

    Purpose: Evidence points towards activation of the mineralocorticoid receptor (MR) to be involved in CNI nephrotoxicity. The SPIREN trial was designed to test the hypothesis…
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