ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    MicroRNA let-7i Regulates Dendritic Cells Maturation Targeting Interleukin-10 via JAK1-STAT3 Signal Pathway Subsequently Induces Prolonged Cardiac Allograft Survival in Rats.

    X. Jin,1 Y. Sun,2 X. Liu,2 J. Wang,1 S. Xu,1 L. Yao,1 Z. Zhao,3 L. Jiang,4 Q. Wu,5 J. Wu.2

    1Thoracic Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China; 2Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China; 3Pediatric Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China; 4Otorhinolaryngology, The First Affiliated Hospital of Harbin Medical University, Harbin, China; 5Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

    Background:Our previous study demonstrated that microRNA (MiR) let-7i could regulate dendritic cells (DCs) maturation and functional state via targeting SOCS1. In this study, we investigated…
  • 2016 American Transplant Congress

    Multiplex Profiling of Plasma Proteins After Xenogenic Lung Exposure.

    A. Azimzadeh,1 N. Cheng,1 X. Cheng,1 E. Schwartz,1 L. Burdorf,1 S. Dahi,1 N. Kubicki,1 D. Parsell,1 T. Zhang,1 D. Cooper,2 C. Phelps,3 D. Ayares,3 R. Pierson III.1

    1Univ. Of Maryland, Baltimore, MD; 2University of Pittsburgh, Pittsburgh, PN; 3Revivicor, Blacksburg, VA.

    Background: Porcine lungs exhibit injury by human blood and are only partially protected in GalTKO organs with additional human membrane cofactor protein (hCD46). Residual injury…
  • 2016 American Transplant Congress

    Why Are Pancreas Transplants Declining in the United States in the Past Decade?

    R. Stratta,1 A. Gruessner,2 J. Odorico,3 J. Fridell,4 J. Rogers,1 A. Farney,1 G. Orlando,1 R. Gruessner.2

    1Surgery, Wake Forest, Winston-Salem, NC; 2Surgery, SUNY Upstate, Syracuse, NY; 3Surgery, University of Wisconsin-Madison, Madison, WI; 4Surgery, Indiana University, Indianapolis, IN.

    In the past decade, the annual number of pancreas transplants (PTxs) in the US has steadily declined coincident with increasing numbers of PTxs performed outside…
  • 2016 American Transplant Congress

    London Criteria for Listing Potential Liver Transplant Jehovah's Witness (JW) Patients. A Single Centre Results of Listing and Liver Transplant (LT) in JW Patients in Canada.

    H. Sharma, I. Al-Hasan, K. Pineda-Solis, M. Tun, P. Marotta, D. Quan, M. Levstik.

    Multi Organ Transplantation Unit, London Health Sciences Centre, London, Canada.

    Background: There is paucity of Level A evidence of consistent listing criteria and Liver Transplant in Jehovah Witness (JW) patients. London Health Sciences Centre (LHSC)…
  • 2016 American Transplant Congress

    Utility of a Scoring Tool for Living Kidney Donor Volunteers.

    S. Lien,1 L. Willey,2 A. Lecuyer-Koich,2 M. Voges,2 T. Dunn.2

    1Marian University School of Medicine, Indianapolis, IN; 2Division of Transplant Surgery, University of Minnesota, Minneapolis, MN.

    A comprehensive yet efficient evaluation of living kidney donor volunteers (LKDV) is key to a successful transplant program. Donor selection is complex and must balance…
  • 2016 American Transplant Congress

    Impact of HLA-DR Compatibility on Efficacy Outcomes and Renal Function in Kidney Transplant Recipients Following Early Switch from Calcineurin Inhibitor to Everolimus: Subanalysis from the ELEVATE Study.

    J. Cruzado, H. Holdaas, P. Lopez, J. Aguilar, G. Dong, F. Claas, W. Arns, M. van der Giet, J. de Fijter.

    ELEVATE study group, Llobregat Catalunya, Spain.

    Background: Human leukocyte antigen (HLA) compatibility between donor and recipient is considered an important factor for graft outcomes. Compatibility is associated with a lower incidence…
  • 2016 American Transplant Congress

    Evaluation of an Early Steroid Withdrawal Maintenance Regimen in African American Renal Transplant Recipients.

    S. Gabardi, M. Kim, R. Alsheikh, K. Townsend, A. Chandraker.

    Brigham and Women's Hospital, Boston, MA.

    Introduction: Outcomes in African American (AA) transplant recipients are inferior to other ethnic groups. This population also has an accelerated decline in graft function after…
  • 2016 American Transplant Congress

    Donor-Recipient Race Matching Is Not Associated with Recipient Survival Following Heart Transplantation.

    C. Evans,1 P. Sanchez,1 Z. Kon,1 E. Feller,2 B. Griffith,1 S. Pham.1

    1Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD; 2Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Purpose: The implications of donor and recipient race matching in heart transplantation are not clear. The objective of this communication is to quantify the association…
  • 2016 American Transplant Congress

    Calcineurin Inhibitor (CNI) Delay with ATG Induction: Teaching an Old Dog, New Tricks.

    A. Aliabadi,1 J. Goekler,1 O. Salameh,1 T. Haberl,1 B. Steinlechner,2 P. Opfermann,2 A. Kaider,1 K. Uyanik-Uenal,1 G. Laufer,1 A. Zuckermann.1

    1Cardiac Surgery, Medical University of Vienna, Vienna, Austria; 2Cardiothoracic and Vascular Anaesthisiology, Medical University of Vienna, Vienna, Austria.

    CNI delay early after heart transplantation is a recommended therapeutic option according to ISHLT guidelines. However, there exist only few published data on feasibility of…
  • 2016 American Transplant Congress

    Air Pollution – An Additional Risk Factor for Developing Cardiac Allograft Vasculopathy.

    C. Bara, D. Böthig, Y. Scheibner, D. Bobylev, B. Przybylek, A. Haverich.

    Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    Purpose:Cardiac allograft vasculopathy (CAV) remains one of the primary causes of death in long-term follow-up after heart transplantation (HTx) and is the most limiting factor…
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