ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Similar Kidney Allograft and Patient Survival in Native Americans Despite Lower Rates of Living Donation and Longer Wait on the Deceased Donor List.

    H. Khamash,1 K. Reddy,2 H. Chakkera,1 J. Huskey,1 S. Sukumaran-Nair,1 A. Mathur,2 A. Moss,2 N. Katariya,2 A. Singer,2 R. Heilman.1

    1Nephrology, Mayo Clinic Arizona, Phoenix; 2Transplant Surgery, Mayo Clinic Arizona, Phoenix.

    Previous studies have shown that Native Americans (NAs) have decreased access and inferior outcomes following kidney transplantation. Reviewing our center's experience we wanted to assess…
  • 2016 American Transplant Congress

    Impediments to Timely Listing for HIV+ Patients Being Evaluated for Kidney Transplantation.

    D. Lee,1 A. Aldea,1 M. Harhay,2 S. Akshay,2 G. Malat,3 N. Law,1 S. DeBellis,2 T. Bias,1 S. Boyle,2 K. Ranganna,2 A. Doyle.2

    1Division of Infectious Diseases and HIV Medicine, Drexel University, Philadelphia; 2Division of Nephrology, Drexel University, Philadelphia; 3Department of Surgery, Drexel University, Philadelphia.

    Introduction:HIV+ individuals can be transplanted safely and effectively but face additional barriers in evaluation and listing.MethodsWe performed a single center chart review of all HIV+…
  • 2016 American Transplant Congress

    The Immunologic Profile of Brain Death in Humans: A Whole-Body Analysis.

    D. Carpenter,1,2 N. Matsuoka,1 J. Thome,1,3 T. Granot,1,3 C. Gordon,1,3 B. Kumar,1,3 T. Senda,1,3 M. Miron,1,3 J. Weiner,2 A. Griesemer,1,2 D. Farber.1,2,3

    1Columbia Center for Translational Immunology, Columbia University Medical Center, New York City, NY; 2Surgery, Columbia University Medical Center, New York City, NY; 3Microbiology and Immunology, Columbia University Medical Center, New York City, NY.

    Transplantation outcomes are believed to be influenced by a generalized inflammatory state caused by brain death itself or events in the peri-transplant period. Studies on…
  • 2016 American Transplant Congress

    Stratification of Kidney Transplant Recipients into Those with Low and High Alloreactive T-Cells May Allow Safe Conversion to mTOR-Inhibitor-Based Immunosuppression.

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    ZEUS and Herakles study randomized kidney transplant recipients (KTRs) to either continue cyclosporine or convert to everolimus posttransplantation with favorable long-term outcomes in the conversion…
  • 2016 American Transplant Congress

    Clinical Outcomes of Simplified Once-Daily Immunosuppressive Regimen for Kidney Recipients.

    C.-K. Oh,1 S.-J. Kim,2 K. Huh,3 S. Kim,4 H. Cho,5 S. Lee.6

    1Surgery, Ajou University School of Medicine, Suwon, Republic of Korea; 2Surgery, Samsung Medical Center, Seoul, Republic of Korea; 3Surgery, Yonsei University Health System, Seoul, Republic of Korea; 4Surgery, CHA University School of Medicine, Pocheon, Republic of Korea; 5Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 6Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.

    Background. Many of immunosuppressive drugs have been prescribed as twice-daily dosing. Simplified once-daily dosing of the entire drug regimen can enable patients to improve treatment…
  • 2016 American Transplant Congress

    Exosomes Expressing Cardiac Self-Antigens (Myosin and Vimentin) and Immuno-Regulatory miRNA Induce Graft Rejection.

    M. Sharma,1,2 M. Gunasekaran,1,2 Z. Xu,1,2 N. Steward,1 W. Liu,1,2 N. Benshoff,1 T. Mohanakumar.1,2

    1Washington Univ Sch Med, St. Louis, MO; 2Norton Thoracic Institute - St. Joseph's Hospital, Phoenix, AZ.

    Heart transplantation (HTx) remains an option for patients with cardiac diseases. However, humoral and cell mediated immune responses represent a major obstacle for long-term survival.…
  • 2016 American Transplant Congress

    Qualitative Assessment of Patient-Perceived Treatment Burden Following Cardiac Transplantation.

    K. Deininger,1 J. Reich,1 J. Hirsch,2 S. Graveline,2 A. Feist,2 J. LaFleur,3 S. Smith,4 A. Ambardekar,1 J. Lindenfeld,5 C. Aquilante.1

    1University of Colorado, Aurora, CO; 2University of California San Diego, La Jolla, CA; 3University of Utah, Salt Lake City, UT; 4University of Florida, Gainesville, FL; 5Vanderbilt University, Nashville, TN.

    Patient-perceived treatment burden (PPTB), i.e., “the work of being a patient,” following heart transplantation (HTx) can affect patients' experiences of care, sense of self-efficacy in…
  • 2016 American Transplant Congress

    Only 13% of Liver Transplant (LT) Recipients with Moderate to Severe Kidney Disease (KD) Tolerate Conversion to Everolimus and Reduced Tacrolimus (EVR/rTac).

    S.-H. Pan, I. Kim, A. Klein, A. Annamalai, T. Todo, N. Nissen.

    Liver Transplant, Cedars-Sinai Medical Center, Los Angeles, CA.

    EVR/rTac has been reported to improve renal function in LT recipients with adequate kidney function (eGFR > 80ml/min); however, this strategy in LT patients with…
  • 2016 American Transplant Congress

    Adopting the Kidney Donor Profile Index (KDPI)/Kidney Donor Risk Index (KDRI) for Japanese Donors After Cardiac Death.

    M. Kusaka,1 A. Kawai,1 N. Fukami,1 H. Sasaki,1 H. Takahashi,2 T. Ito,3 T. Kenmochi,3 R. Shiroki,1 K. Hoshinaga.1

    1Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 2Division of Medical Statistics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 3Organ Transplant Surgery, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.

    Introduction: Due to a severe organ shortage, it is important to predict the outcome of grafts prior to kidney transplantation and establish an appropriate allocation…
  • 2016 American Transplant Congress

    The UKKDRI Score Predicts Outcomes of Deceased Donor Transplantation Using a Steroid Sparing Immunosuppressive Protocol.

    A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.

    Imperial College REnal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    The UK kidney donor risk-index (UKKDRI) was developed to provide a simplistic clinical tool to help determine quality of an allograft and aid informed consent.…
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