2016 American Transplant Congress
Sepsis Prolongs Allograft Survival Compared with Non-Septic Infection in a Murine Model of Skin Transplantation and Pseudomonas aeruginosa Pneumonia.
Emory Transplant Center, Department of Surgery, Emory University, Atlanta, GA.
Concurrent infections have been shown to increase risk of transplant rejection via enhanced innate immune activation and increased T cell alloreactivity. In some cases, these…2016 American Transplant Congress
Rapamycin Prolongs Cardiac Allograft Survival in a Mouse Model by Inducing Myeloid-Derived Suppressor Cells.
Mammalian target of rapamycin (mTOR) inhibitors are the main immunosuppressive drugs for organ transplant recipients. Nevertheless, the mechanisms by which mTOR inhibitors induce immunosuppression is…2016 American Transplant Congress
Neighborhood Poverty and Gender Disparities in Access to Live Donor Kidney Transplantation.
Women are less likely to receive a live donor kidney transplant (LDKT) than men, but little is known about the contribution of poverty to this…2016 American Transplant Congress
Increasing Volume and Improved Survival in Solid Organ Transplantation for Amyloidosis – An Analysis of the UNOS Database.
Background: Amyloidosis is a rare disease that results from accumulation of inappropriately folded proteins causing organ failure and poor prognosis. In the last decade several…2016 American Transplant Congress
Survival Benefit of Kidney Transplantation in US Adults with Sickle Cell Nephropathy.
End-stage renal disease (ESRD) patients with sickle cell nephropathy (SCN) are less likely to receive a kidney transplant (KT) than ESRD patients without SCN. Comparing…2016 American Transplant Congress
Rapid Withdrawal of Donation After Cardiac Death Donors.
1Surgery, University of California-San Diego, La Jolla, CA; 2Lifesharing, San Diego, CA.
Purpose: Potential organ donors may be lost if procurement needs to occur emergently due to hemodynamic instability or family request, in particular if serologies and…2016 American Transplant Congress
Rapid Discontinuation of Prednisone (RDP) in Kidney Transplant (KTx) Recipients: 15-Year Outcomes.
PURPOSE: RDP after KTx is associated with increased early rejection; no decrease in medium‐term patient (PS) or graft survival (GS); and significantly decreased prednisone‐related side…2016 American Transplant Congress
The BEST Trial: A Prospective Randomized Trial of Belatacept-Based, CNI- and Corticosteroid-Free Immunosuppression.
Efficacy of CNI- and corticosteroid-free immunosuppressive regimens has not been demonstrated in large, multicenter trials. BEST (Belatacept-based Early Steroid Withdrawal Trial) (NCT 01729494) compares 2…2016 American Transplant Congress
Gene Expression Levels of Advanced Heart Failure Patients in Terms of Coagulation and Its Effect within Multiple Organ Dysfunction Syndrome.
Medicine Cardiology, UCLA, Los Angeles, CA.
MOD is progressive organ failure amongst 2 or more organs. Innate-immunity/inflammation-related coagulopathies can cause disseminated clotting in vasculature leading to organ failure. Purpose is to…2016 American Transplant Congress
Clostridium difficile Infection in Patients with a Continuous Flow, Durable Left Ventricular Assist Device.
NewYork-Presbyterian Hospital, Columbia University, New York.
Clostridium difficile infection (CDI) increases morbidity and mortality in hospitalized patients. Patients with a ventricular assist device (VAD) are exposed to known risk factors for…
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