2016 American Transplant Congress
Analysis of T Cell Receptor Repertoire in Routine Renal Allograft Biopsy.
Introduction: Diversity and clonality of the T cell repertoire of circulating and tissue-resident T-cells can be assessed by sequencing of recombined T cell receptor (TCR)…2016 American Transplant Congress
Dysfunctional Production of Adipocytokines in Obesity Results in Inferior Oncologic Outcomes from Hepatocellular Carcinoma Following Liver Transplantation.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionOver 2 billion people worldwide are obese. There is strong evidence of an association between obesity and hepatocellular (HCC) cancer.This effect is mediated through an…2016 American Transplant Congress
Barriers to the Wider Utilization of Living Donor Liver Transplantation (LDLT).
Purpose: LDLT reduces waitlist mortality, improves access to transplantation and has post-transplant outcomes that are equivalent to or better than deceased donor transplant. Despite these…2016 American Transplant Congress
Functional Capacity Pre-Transplantation Measured by 6 Minute Walk Test and Clinical Outcomes.
Background:The 6 minute walk is an inexpensive, low-technology test for measuring a patient's functional capacity and overall fitness. The utility of 6 minute walk test…2016 American Transplant Congress
Acute Rejection: A Major Cause of Death-Censored Kidney Allograft Failure.
1Weill Medical College of Cornell University, New York; 2The Rogosin Institute, New York.
Introduction:The role of acute rejection as a cause of kidney allograft failure is not well defined in the current era of immunosuppression. We analyzed the…2016 American Transplant Congress
Impact of Pre-Existing Comorbidities on Long-Term Patient and Graft Survival in Kidney Transplant Recipients.
Nephrology, Charité University, Berlin, Germany.
BACKGROUND Outcomes of patients with end-stage renal disease are largely affected by their comorbidities. Detailed data evaluating the impact of pre-transplant comorbidities on the long-term…2016 American Transplant Congress
Monocytic TNF-α Response to EBV Peptides as a Mean to Identify Over-Immunosuppressed Kidney Transplant Recipients.
Background. The reduction in acute rejection rates seen with the current triple immunosuppressive maintenance regimen has come at the expense of an increased risk of…2016 American Transplant Congress
Kidney Survival Outcomes in Combined Intestinal-Kidney Transplant: An Analysis of the UNOS/OPTN Database 2000-2014.
Medicine/Nephrology, Indiana University, Indianapolis.
Background: Intestinal transplants (isolated/modified/multi-visceral) carry a high morbidity and mortality. Kidney outcomes after combined intestinal (IT) with kidney transplant (CIKT) remain largely uninvestigated.Methods: The UNOS…2016 American Transplant Congress
Activation of Alloreactive T Cells by Allogeneic Exosomes and Cells Cross-Dressed with Allogeneic MHC Molecules.
Our recent studies have documented the presence of high numbers of recipient antigen presenting cells (APCs) displaying donor MHC molecules (cross-dressed) on their surface after…2016 American Transplant Congress
Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.
Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…
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