ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Early Onset Hyperuricemia Is a Prognostic Marker for Kidney Allograft Dysfunction.

    M. Han,1 S. Yang,2 I. Jung,3 S.-K. Park,4 Y. Kim,5 D. Han,5 Y. Kim,1 S. Kim,6 J. Lee.7

    1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Kidney Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea; 3Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 4Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Republic of Korea; 5Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Republic of Korea; 6Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea; 7Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.

    Aim: It is not certain whether hyperuricemia is a true risk factor of kidney allograft failure. We investigated the association of hyperuricemia and graft outcome.Methods:…
  • 2016 American Transplant Congress

    Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.

    A. Mehta,1 A. Marriott,1 A. Ghazanfar.2

    1St. George's, University of London, London, United Kingdom; 2Renal Transplant Unit, St. George's Hospital, London, United Kingdom.

    This study aims to analyze our renal transplant recipient population in terms of perioperative complications (90 day) and graft survival (3 years) in relation to…
  • 2016 American Transplant Congress

    Association Between GFR Decline and Long Term Outcome in Renal Transplantation.

    A. Delay,1 O. Moranne,2 N. Maillard,1 E. Alamartine,1 C. Mariat.1

    1Nephrology Department, CHU, Saint Etienne, France; 2Nephrology Department, CHU, Nimes, France.

    In renal transplantation, GFR decline is strongly associated to graft failure and patient death and thus could be an interesting proxy for clinical research. GFR…
  • 2016 American Transplant Congress

    Chemoprevention of Cutaneous Squamous Cell Carcinoma in Renal Transplant Recipients: A Case-Controlled Analysis.

    R. Anand, R. Hung, S. Frame, K. Bramham, M. Wain, A. Cronin.

    Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.

    Organ transplant recipients are up to 200 times more likely to develop cutaneous squamous cell carcinoma (SCC) than age-matched general populations. Systemic retinoids, such as…
  • 2016 American Transplant Congress

    Donor Risk Index for Intestinal & Multi-Visceral Transplantation.

    G. Zeng,1 M. Chen,2 X. Zhao,3 D. Landsittel,2 H. Sogawa.4

    1Department of Pathology, The Thomas E Starzl Transplantation Institute, Pittsburgh, PA; 2Division of General Internal Medicine, Department of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, PA; 3Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China; 4Multi-Organ Transplant & Hepatobiliary, Westchester Medical Center, Valhalla, NY.

    Background: The Donor Risk Index and the Kidney Donor Profile Index (KDPI) have been utilized for liver and kidney transplantation in clinical and research setting.…
  • 2016 American Transplant Congress

    Eomesodermin Expression by CD8+ Alloreactive T Cells in Human and Nonhuman Primate Allograft Recipients.

    A. Perez-Gutierrez, L. Lu, A. Zahorchak, Y. Ono, A. Thomson, M. Ezzelarab.

    Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    Background:The transcription factor Eomesodermin (Eomes) is critical in the maintenance of antigen-specific memory T cells (Tmem). We have shown previously that prolonged kidney allograft survival…
  • 2016 American Transplant Congress

    Belatacept Immunotherapy Is Not Augmented by Blockade of Activated LFA-1 in a Nonhuman Primate Renal Transplant Model.

    K. Samy,1 M. Mulvihill,1 B. Collins,1 D. Lo,2 M. Song,1 F. Leopardi,1 A. Kirk.1,2

    1Department of Surgery, Duke University Medical Center, Durham, NC; 2Emory University, Atlanta, GA.

    Purpose: Belatacept specifically targets de novo alloimmune responses without off target side effects. However, resistant alloreactive memory T cells have complicated its use. LFA-1 therapy…
  • 2016 American Transplant Congress

    One-Year Graft Loss Risk in Kidney Transplants – A Big Data Approach.

    T. Srinivas, D. Taber, J. Zhang, Z. Su, J. Marsden, A. Tripathi, W. Moran, P. Mauldin.

    MUSC, Charleston, SC; IBM Corp., Armonk.

    Background Predictive models using national data are limited by lack of evolving patient level data. A Big Data approach using both static and dynamic variables…
  • 2016 American Transplant Congress

    Similar Kidney Allograft and Patient Survival in Native Americans Despite Lower Rates of Living Donation and Longer Wait on the Deceased Donor List.

    H. Khamash,1 K. Reddy,2 H. Chakkera,1 J. Huskey,1 S. Sukumaran-Nair,1 A. Mathur,2 A. Moss,2 N. Katariya,2 A. Singer,2 R. Heilman.1

    1Nephrology, Mayo Clinic Arizona, Phoenix; 2Transplant Surgery, Mayo Clinic Arizona, Phoenix.

    Previous studies have shown that Native Americans (NAs) have decreased access and inferior outcomes following kidney transplantation. Reviewing our center's experience we wanted to assess…
  • 2016 American Transplant Congress

    Impediments to Timely Listing for HIV+ Patients Being Evaluated for Kidney Transplantation.

    D. Lee,1 A. Aldea,1 M. Harhay,2 S. Akshay,2 G. Malat,3 N. Law,1 S. DeBellis,2 T. Bias,1 S. Boyle,2 K. Ranganna,2 A. Doyle.2

    1Division of Infectious Diseases and HIV Medicine, Drexel University, Philadelphia; 2Division of Nephrology, Drexel University, Philadelphia; 3Department of Surgery, Drexel University, Philadelphia.

    Introduction:HIV+ individuals can be transplanted safely and effectively but face additional barriers in evaluation and listing.MethodsWe performed a single center chart review of all HIV+…
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